1,015 research outputs found

    Studying the effect of multisource Darwinian particle swarm optimization in search and rescue missions

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    Robotic Swarm Intelligence is considered one of the hottest topics within the robotics research eld nowadays, for its major contributions to di erent elds of life from hobbyists, makers and expanding to military applications. It has also proven to be more effective and effcient than other robotic approaches targeting the same problem. Within this research, we targeted to test the hypothesis that using more than a single starting/ seeding point for a swarm to explore an unknown environment will yield better solutions, routes and cover more area of the search space within context of Search and Rescue applications domain. We tested such hypothesis via extending existing Particle swarm optimization techniques for search and rescue operations (i.e. Robotic Darwinian Particle Swarm Optimization and we split the swarm into smaller groups that start exploration from di erent seed positions, then took the convergence time average for di erent runs of simulations and recorded the results for quanti cation. The results presented in this work con rms the hypothesis we started with, and gives insight to how the number of robots contributing in the experiments a ect the quality of the results. This work also shows a direct correlation between the swarm size and the search space

    Gravity theory in SAP-geometry

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    The aim of the present paper is to construct a field theory in the context of absolute parallelism (Teleparallel) geometry under the assumption that the canonical connection is semi-symmetric. The field equations are formulated using a suitable Lagrangian first proposed by Mikhail and Wanas. The mathematical and physical consequences arising from the obtained field equations are investigated.Comment: 14 pages, References added and a reference updated, minor correction

    Prevalence of asymptomatic bacteriuria among low risk pregnant women attending antenatal care clinic in tertiary hospital: a cross sectional study

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    Background: The current study aims to identify the prevalence of asymptomatic bacteriuria among low-risk pregnant women attending the antenatal care clinic of tertiary University Hospital and to detect the most common causative organisms.Methods: A prospective cross-sectional study conducted at a tertiary University Hospital in the period between 1st November 2017 and 31st June 2018. All eligible women attending the outpatient clinic for antenatal care were approached to participate in the study. The recruited women were assessed through detailed history and clinical examination. Urine samples were taken for culture and sensitivity within two hours, in order to avoid bacterial multiplication. Urine culture and antibiotic sensitivity test were done.Results: The study included 250 women. The mean age of included women was 25.89±5.49 (18-42 years). The urine analysis results showed that 32% of cases had pus cells >5 per high power field and 10.4% of cases have protein (+). Casts were present in 0.8% of cases. RBCs >5 per high power field were present in 4.8% of cases. ASB is defined as urine culture with more than 100,000 colony forming unit; this was present in 30 cases. This indicates that the prevalence of ASB among studied cases was 12%. Enterococcus was the most prevalent organism as it was present in 36.7% among positive cases. Antibiotic sensitivity test was performed to the growing organisms indicated that teicoplanin, imipenem, cefoxitin, cefotaxime + clavulanic acid, Entrapenem, and trimethoprim + sulfamethoxazole are the most effective antibiotics against the most common organisms causing asymptomatic bacteriuria.Conclusions: The prevalence of asymptomatic bacteriuria among low-risk pregnant women is about 12%. Urine culture for asymptomatic bacteriuria should be the standard of care for evaluation of pregnant patient during antenatal care as regard presence or absence of UTI

    Linear Connections and Curvature Tensors in the Geometry of Parallelizable Manifolds

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    In this paper we discuss curvature tensors in the context of Absolute Parallelism geometry. Different curvature tensors are expressed in a compact form in terms of the torsion tensor of the canonical connection. Using the Bianchi identities some other identities are derived from the expressions obtained. These identities, in turn, are used to reveal some of the properties satisfied by an intriguing fourth order tensor which we refer to as Wanas tensor. A further condition on the canonical connection is imposed, assuming it is semi-symmetric. The formulae thus obtained, together with other formulae (Ricci tensors and scalar curvatures of the different connections admitted by the space) are calculated under this additional assumption. Considering a specific form of the semi-symmetric connection causes all nonvanishing curvature tensors to coincide, up to a constant, with the Wanas tensor. Physical aspects of some of the geometric objects considered are mentioned.Comment: 16 pages LaTeX file, Changed title, Changed content, Added references, Physical features stresse

    Flash flood susceptibility assessment in Jeddah city (Kingdom of Saudi Arabia) using bivariate and multivariate statistical models

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    The city of Jeddah (Saudi Arabia) has experienced two catastrophic flash flood events in 2009 and 2011. These flood events had catastrophic effect on human lives and livelihoods around the wadi Muraikh, wadi Qus, wadi Methweb, and wadi Ghulail in which 113 people were dead and with 10,000 houses and 17,000 vehicles were damaged. Thus, a comprehensive flood management is required. The flood management requires information on different aspects such as the hydrological, geotechnical, environmental, social, and economic aspects of flooding. Flood susceptibility mapping for any area helps the decision makers to understand the flood trends and can aid in appropriate planning and flood prevention. In this study, two models were used for the generation of flood susceptibility maps for the Jeddah region. The first model includes bivariate probability analysis (frequency ratio), and the second model uses the multivariate analysis. For the multivariate model, the acquired weights of the FR model were entered into the logistic regression model to evaluate the correlation between flood occurrence and each related factor. This integration will overcome some of the weakness of the logistic regression, and the performance the LR will be enhanced. A flood inventory map was prepared with a total of 127 flood locations. These flood locations were extracted from different sources including field investigation and high-resolution satellite image (IKONOS 1 m). These flood locations were randomly split into two groups, one dataset representing 70 % was used for training the models, and the remaining 30 % was used for models validation. Various independent flood-related factors such as slope, elevation, curvature, geology, landuse, soil drain, and distance from streams were included. The impact of each independent flood-related factors on flooding was evaluated by analyzing each independent factor with the historical flood inventory data. The training and validation datasets were used to evaluate the flood susceptibility maps using the success and the prediction rate methods. The results of the accuracy assessment showed a success rate of 90.4 and 91.6 % and a prediction rate of 89.6 and 91.3 % for FR and ensemble FR and LR models, respectively. In addition, a comparison has been made between real flood events in 2009 and the resultant susceptibility maps. Hence, it is concluded that the FR and ensemble Fr and LR models can provide an acceptable accuracy in the prediction of flood susceptibility in the Saudi Arabia. Our findings indicated that these flood susceptibility maps can assist planners, decision makers, and other agencies to deal with the flood management and planning in the area

    Remote sensing-based studies coupled with field data reveal urgent solutions to avert the risk of flash floods in the Wadi Qus (east of Jeddah) Kingdom of Saudi Arabia

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    On November 25, 2009, heavy amount of rainfall precipitated in the city of Jeddah that led to floods causing unexpected loss of life (113 person died), and damaged public and private properties (10,000 cars were damaged/destroyed, and many houses, roads, highways, and industrial properties were also affected). The city of Jeddah is located within an independent mega drainage basin with a surface area of 1,760 km2. This mega basin is divided into three major sub-basins (northern, middle, and southern). Wadi Qus is located in the southern sub-basin with an area of ~63 km2. It passes through many of the neighborhoods such as Al-Harazat, Al-Sawaid, Queza, Al-Mesaid, Al-Haramin Highway, and the King Abdel Aziz University. These areas were severely damaged during the flash flood event in 2009. The current study deals with the determination of the best sites for the construction of flood control dams, followed by a number of detailed studies to ensure that these selected sites are appropriate. Geological, geotechnical, geophysical, and hydrological investigations were conducted to identify the types of rocks, the subsurface conditions, and the geotechnical properties of abutment and subsurface of soil and rock in the dam sites. The study found that there are three locations that can be appropriate for the construction of the flood control dams at Wadi Qus. Hydrological studies indicated that the runoff volumes for sub-basins B1, B2, and B3 are 2,102,709, 1,023,156, and 4,868,304 m3, respectively, for 500-year return period and 2,356,081, 1,149,687, and 5,451,123 m3, respectively, for 1,000-year return period. Comparing these values with the reservoir volumes calculated from the detailed ground survey with different dam’s height, it was found that dam’s heights of 15.5, 11.5, and 13.5 m for dams Q01, Q02, and Q03, respectively, are adequate for different basin volumes for 1,000-year return periods. Finally, the conceptual designs have been prepared and recommended for these dams

    Novel Quinuclidinone Derivatives Induced Apoptosis in Human Breast Cancer via Targeting P53

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    Small molecules that can target human cancers have been highly sought to increase the anticancer efficacy, the present work describes the design and synthesis of novel series of five quinuclidinone derivatives (2a-2e). Their anticancer activities were investigated against breast cancer cells MCF-7, MDA-MB-231 breast cancer cells harboring mutant p53 and normal breast counterpart MCF-12a. Derivative 2e reduced proliferation of MCF-7 and MCD-12a while it has no effect on MDA-MB-231. Derivative 2e induced apoptosis in MCF-7 cells which is further confirmed by TUNEL assay and it reduced the percentage of cell in G2/M phase as confirmed by increased expression of cyclin B and reduced expression of cyclinD1. Derivative 2e reduced expression levels of Mdm2, Akt and ERK1/2 by and increased expression level of p53. Moreover, the apoptosis induction by 2e was also inhibited by PFT-α as evidenced by non-significant induction of apoptosis after treatment of MCF-7 cells with both derivative 2e and PFT-α. In addition, docking study reveals that derivative 2e has a binding pattern close to the pattern observed in the structure of the lead fragment 5,6-dimethoxy-2-methylbenzothiazole bound to T-p53C-Y220C. The above findings demonstrate that derivative 2e induces apoptosis in MCF-7 cells via targeting p53 which merits further development

    Assessment of rock slope stability and structurally controlled failures along Samma escarpment road, Asir Region (Saudi Arabia)

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    Samma escarpment road is located in Asir Region, Saudi Arabia. It is located NW of Abha city. This escarpment road represents a major corridor in the area which connects different cities and touristic resorts in the region. It is descended from Sudah plateau at about 2700 m above sea level (asl) toward Wadi al Aws at about 1500 m asl. The total length of the road section is about 8 km which is passing through a highly mountainous area characterized by a complex geological and structural elements. This road has been exposed to frequent slope failures from time to time due to various factors such as intense rain storms, different geological and structural elements (weak rocks, shear zones, and faults), road characteristics (different horizontal/vertical curvatures and narrow road section), and human activities (uncontrolled rock cuts). Many sliding events have been documented along this escarpment road, particularly during and following rainstorms. The purpose of this paper is to evaluate the geology and structures by applying the rock mass rating (RMR) and slope stability (structurally controlled failures) along the Samma escarpment road. The stability analysis was performed using two Dips and RockPack III programs with the help of RocLab software. The Summa escarpment rock cuts were classified into 51 stations which were investigated in detail. Results indicated that most rock stations are poor quality, and 31, 32, and 41 stations are stable, 4, 6, and 7 stations are marginally stable, and 16, 13, and 3 stations are potentially unstable due to planar, wedge, and toppling failures, respectively. Finally, different recommendations and remediation methods were suggested as mitigation measures

    Stability of Rock Slopes along Raidah Escarpment Road, Asir Area, Kingdom of Saudi Arabia

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    The Raidah Escarpment road is located north west of Abha city, Asir region, Kingdom of Saudi Arabia. This escarpment road represents an important corridor in the area which connects different villages and tourist resorts with each other. The total length of this road section is about 9 km which passes through a highly mountainous area. The road also passes through areas of different geological hazards (rock, debris flow, soil, and weathered zones). The different environmental factors (e.g. intensive rainy summer), variable geological and structural elements (weak rocks, slide debris weak soils, shear zones, and faults) difficult road characteristics (narrow roads with tight horizontal andvertical curvature) and various human activities in the area make the road susceptible to frequent slope failures (rockfalls, rock sliding, debris flow, soil slides, and raveling) from time to time. This paper deals with the evaluation of the stability of the rock cuts along the Raidah escarpment road using two methods including a structural controlled method and a raveling type method. Raidah escarpment rock cuts have been classified into sixty nine stations which were investigated and subsequently rated. Results of this study indicated that: (1) Based on the structiural control mode of failures, it was found that 12 stations are potentially unstable due to planar, wedge, and toppling failures, and out of them five stations have a major impact on the road in the event of failure, including stations 11, 17, 20, 31, and 40. (2) According to the Modified Colorado Rockfall hazard rating system, it was found that 13, 12, 13, 17, and 49 stations are of high, high to moderate, moderate, moderate to low, and low hazard. On the other hand, it was found that 13, 11, 11, and 69 stations have a high, high to moderate, moderate, and low impact on the road in the case of failure. (3) According to the field simulation tests it was found that 6 stations potentially show highly problems from rolling and bouncing rocks. However, out of these sites it was found that only 4 stations have a high impact on the road due to rolling and bouncing. (4) the areas that are impacted by the debris flows have been mapped and determined. Finally, different recommendations and remediation methods have been discussed to minimise the impact of problimatic sites
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