Thermal runaway of metal nano-tips during intense electron emission

When an electron emitting tip is subjected to very high electric fields, plasma forms even under ultra high vacuum conditions. This phenomenon, known as vacuum arc, causes catastrophic surface modifications and constitutes a major limiting factor not only for modern electron sources, but also for many large-scale applications such as particle accelerators, fusion reactors etc. Although vacuum arcs have been studied thoroughly, the physical mechanisms that lead from intense electron emission to plasma ignition are still unclear. In this article, we give insights to the atomic scale processes taking place in metal nanotips under intense field emission conditions. We use multi-scale atomistic simulations that concurrently include field-induced forces, electron emission with finite-size and space-charge effects, Nottingham and Joule heating. We find that when a sufficiently high electric field is applied to the tip, the emission-generated heat partially melts it and the field-induced force elongates and sharpens it. This initiates a positive feedback thermal runaway process, which eventually causes evaporation of large fractions of the tip. The reported mechanism can explain the origin of neutral atoms necessary to initiate plasma, a missing key process required to explain the ignition of a vacuum arc. Our simulations provide a quantitative description of in the conditions leading to runaway, which shall be valuable for both field emission applications and vacuum arc studies.Peer reviewe

Do gravitational wave observations in the lower mass gap favor a hierarchical triple origin?

Observations of compact objects in Galactic binaries have provided tentative evidence of a dearth of masses in the so-called lower mass gap $\sim2.2-5$ M$_\odot$. Nevertheless, two such objects have been discovered in gravitational-wave data from LIGO and Virgo. Remarkably, the estimated masses of both secondaries in the coalescences GW190814 ($m_2=2.59^{+0.08}_{-0.09}$M$_\odot$) and GW200210_092254 ($m_2=2.83^{+0.47}_{-0.42}$M$_\odot$) fall near the total mass of $\sim 2.6$ M$_\odot$ of observed Galactic binary neutron star systems. The more massive components of the two binaries also have similar masses. Here we show that a neutron star merger origin of the lighter components in GW190814 and GW200210_092254 is favored over $M^{-2.3}$ (Bayes factor $\mathcal{B}\sim 5$) and uniform ($\mathcal{B}\sim 14$) mass distributions in the lower mass gap. We also examine the statistical significance of the similarity between the heavier component masses of GW190814 and GW200210_092254, and find that a model in which the mass of GW200210_092254 is drawn from the mass posterior of GW190814 is preferred ($\mathcal{B}\sim 18$) to a model in which its mass is drawn from the overall mass distribution of black holes detected in gravitational wave events. This hints at a common origin of the primary masses, as well as the secondary masses, in GW190814 and GW200210_092254.Comment: 6 pages, 2 figure

Artificial Precision Timing Array: bridging the decihertz gravitational-wave sensitivity gap with clock satellites

Gravitational-wave astronomy has developed enormously over the last decade with the first detections across different frequency bands, but has yet to access $0.1-10$ $\mathrm{Hz}$ gravitational waves. Gravitational waves in this band are emitted by some of the most enigmatic sources, including intermediate-mass binary black hole mergers, early inspiralling compact binaries, and possibly cosmic inflation. To tap this exciting band, we propose the construction of a detector based on pulsar timing principles, the Artificial Precision Timing Array (APTA). We envision APTA as a solar system array of artificial "pulsars"$-$precision-clock-carrying satellites that emit pulsing electromagnetic signals towards Earth or other centrum. In this fundamental study, we estimate the clock precision needed for APTA to successfully detect gravitational waves. Our results suggest that a clock relative uncertainty of $10^{-17}$, which is currently attainable, would be sufficient for APTA to surpass LISA's sensitivity in the decihertz band and observe $10^3-10^4$ $\mathrm{M}_\odot$ black hole mergers. Future atomic clock technology realistically expected in the next decade would enable the detection of an increasingly diverse set of astrophysical sources, including stellar-mass compact binaries that merge in the LIGO-Virgo-KAGRA band, extreme-mass-ratio inspirals, and Type Ia supernovae. This work opens up a new area of research into designing and constructing artificial gravitational-wave detectors relying on the successful principles of pulsar timing.Comment: 10 pages, 3 figure

Characterization of a new full length TMPRSS3 isoform and identification of mutant alleles responsible for nonsyndromic recessive deafness in Newfoundland and Pakistan

BACKGROUND: Mutant alleles of TMPRSS3 are associated with nonsyndromic recessive deafness (DFNB8/B10). TMPRSS3 encodes a predicted secreted serine protease, although the deduced amino acid sequence has no signal peptide. In this study, we searched for mutant alleles of TMPRSS3 in families from Pakistan and Newfoundland with recessive deafness co-segregating with DFNB8/B10 linked haplotypes and also more thoroughly characterized the genomic structure of TMPRSS3. METHODS: We enrolled families segregating recessive hearing loss from Pakistan and Newfoundland. Microsatellite markers flanking the TMPRSS3 locus were used for linkage analysis. DNA samples from participating individuals were sequenced for TMPRSS3. The structure of TMPRSS3 was characterized bioinformatically and experimentally by sequencing novel cDNA clones of TMPRSS3. RESULTS: We identified mutations in TMPRSS3 in four Pakistani families with recessive, nonsyndromic congenital deafness. We also identified two recessive mutations, one of which is novel, of TMPRSS3 segregating in a six-generation extended family from Newfoundland. The spectrum of TMPRSS3 mutations is reviewed in the context of a genotype-phenotype correlation. Our study also revealed a longer isoform of TMPRSS3 with a hitherto unidentified exon encoding a signal peptide, which is expressed in several tissues. CONCLUSION: Mutations of TMPRSS3 contribute to hearing loss in many communities worldwide and account for 1.8% (8 of 449) of Pakistani families segregating congenital deafness as an autosomal recessive trait. The newly identified TMPRSS3 isoform e will be helpful in the functional characterization of the full length protein

Genotype–Phenotype Correlation in DFNB8/10 Families with TMPRSS3 Mutations

In the present study, genotype–phenotype correlations in eight Dutch DFNB8/10 families with compound heterozygous mutations in TMPRSS3 were addressed. We compared the phenotypes of the families by focusing on the mutation data. The compound heterozygous variants in the TMPRSS3 gene in the present families included one novel variant, p.Val199Met, and four previously described pathogenic variants, p.Ala306Thr, p.Thr70fs, p.Ala138Glu, and p.Cys107Xfs. In addition, the p.Ala426Thr variant, which had previously been reported as a possible polymorphism, was found in one family. All affected family members reported progressive bilateral hearing impairment, with variable onset ages and progression rates. In general, the hearing impairment affected the high frequencies first, and sooner or later, depending on the mutation, the low frequencies started to deteriorate, which eventually resulted in a flat audiogram configuration. The ski-slope audiogram configuration is suggestive for the involvement of TMPRSS3. Our data suggest that not only the protein truncating mutation p.T70fs has a severe effect but also the amino acid substitutions p.Ala306Thr and p.Val199Met. A combination of two of these three mutations causes prelingual profound hearing impairment. However, in combination with the p.Ala426Thr or p.Ala138Glu mutations, a milder phenotype with postlingual onset of the hearing impairment is seen. Therefore, the latter mutations are likely to be less detrimental for protein function. Further studies are needed to distinguish possible phenotypic differences between different TMPRSS3 mutations. Evaluation of performance of patients with a cochlear implant indicated that this is a good treatment option for patients with TMPRSS3 mutations as satisfactory speech reception was reached after implantation

An Archival Search for Neutron-Star Mergers in Gravitational Waves and Very-High-Energy Gamma Rays

The recent discovery of electromagnetic signals in coincidence with neutron-star mergers has solidified the importance of multimessenger campaigns in studying the most energetic astrophysical events. Pioneering multimessenger observatories, such as LIGO/Virgo and IceCube, record many candidate signals below the detection significance threshold. These sub-threshold event candidates are promising targets for multimessenger studies, as the information provided by them may, when combined with contemporaneous gamma-ray observations, lead to significant detections. Here we describe a new method that uses such candidates to search for transient events using archival very-high-energy gamma-ray data from imaging atmospheric Cherenkov telescopes (IACTs). We demonstrate the application of this method to sub-threshold binary neutron star (BNS) merger candidates identified in Advanced LIGO's first observing run. We identify eight hours of archival VERITAS observations coincident with seven BNS merger candidates and search them for TeV emission. No gamma-ray emission is detected; we calculate upper limits on the integral flux and compare them to a short gamma-ray burst model. We anticipate this search method to serve as a starting point for IACT searches with future LIGO/Virgo data releases as well as in other sub-threshold studies for multimessenger transients, such as IceCube neutrinos. Furthermore, it can be deployed immediately with other current-generation IACTs, and has the potential for real-time use that places minimal burden on experimental operations. Lastly, this method may serve as a pilot for studies with the Cherenkov Telescope Array, which has the potential to observe even larger fields of view in its divergent pointing mode

Search for Continuous and Transient Neutrino Emission Associated with IceCube's Highest-Energy Tracks: An 11-Year Analysis

IceCube alert events are neutrinos with a moderate-to-high probability of having astrophysical origin. In this study, we analyze 11 years of IceCube data and investigate 122 alert events and a selection of high-energy tracks detected between 2009 and the end of 2021. This high-energy event selection (alert events + high-energy tracks) has an average probability of $\geq 0.5$ to be of astrophysical origin. We search for additional continuous and transient neutrino emission within the high-energy events' error regions. We find no evidence for significant continuous neutrino emission from any of the alert event directions. The only locally significant neutrino emission is the transient emission associated with the blazar TXS~0506+056, with a local significance of $3 \sigma$, which confirms previous IceCube studies. When correcting for 122 test positions, the global p-value is $0.156$ and is compatible with the background hypothesis. We constrain the total continuous flux emitted from all 122 test positions at 100~TeV to be below $1.2 \times 10^{-15}$~(TeV cm$^2$ s)$^{-1}$ at 90% confidence assuming an $E^{-2}$ spectrum. This corresponds to 4.5% of IceCube's astrophysical diffuse flux. Overall, we find no indication that alert events, in general, are linked to lower-energetic continuous or transient neutrino emission.Comment: Accepted by Ap