1,269 research outputs found
Wick's theorem for q-deformed boson operators
In this paper combinatorial aspects of normal ordering arbitrary words in the
creation and annihilation operators of the q-deformed boson are discussed. In
particular, it is shown how by introducing appropriate q-weights for the
associated ``Feynman diagrams'' the normally ordered form of a general
expression in the creation and annihilation operators can be written as a sum
over all q-weighted Feynman diagrams, representing Wick's theorem in the
present context.Comment: 9 page
Mechanisms of linezolid resistance among coagulase-negative staphylococci determined by whole-genome sequencing.
UnlabelledLinezolid resistance is uncommon among staphylococci, but approximately 2% of clinical isolates of coagulase-negative staphylococci (CoNS) may exhibit resistance to linezolid (MIC, ≥8 µg/ml). We performed whole-genome sequencing (WGS) to characterize the resistance mechanisms and genetic backgrounds of 28 linezolid-resistant CoNS (21 Staphylococcus epidermidis isolates and 7 Staphylococcus haemolyticus isolates) obtained from blood cultures at a large teaching health system in California between 2007 and 2012. The following well-characterized mutations associated with linezolid resistance were identified in the 23S rRNA: G2576U, G2447U, and U2504A, along with the mutation C2534U. Mutations in the L3 and L4 riboproteins, at sites previously associated with linezolid resistance, were also identified in 20 isolates. The majority of isolates harbored more than one mutation in the 23S rRNA and L3 and L4 genes. In addition, the cfr methylase gene was found in almost half (48%) of S. epidermidis isolates. cfr had been only rarely identified in staphylococci in the United States prior to this study. Isolates of the same sequence type were identified with unique mutations associated with linezolid resistance, suggesting independent acquisition of linezolid resistance in each isolate.ImportanceLinezolid is one of a limited number of antimicrobials available to treat drug-resistant Gram-positive bacteria, but resistance has begun to emerge. We evaluated the genomes of 28 linezolid-resistant staphylococci isolated from patients. Multiple mutations in the rRNA and associated proteins previously associated with linezolid resistance were found in the isolates investigated, underscoring the multifocal nature of resistance to linezolid in Staphylococcus. Importantly, almost half the S. epidermidis isolates studied harbored a plasmid-borne cfr RNA methylase gene, suggesting that the incidence of cfr may be higher in the United States than previously documented. This finding has important implications for infection control practices in the United States. Further, cfr is commonly detected in bacteria isolated from livestock, where the use of phenicols, lincosamides, and pleuromutilins in veterinary medicine may provide selective pressure and lead to maintenance of this gene in animal bacteria
The Kondo lattice model with correlated conduction electrons
We investigate a Kondo lattice model with correlated conduction electrons.
Within dynamical mean-field theory the model maps onto an impurity model where
the host has to be determined self-consistently. This impurity model can be
derived from an Anderson-Hubbard model both by equating the low-energy
excitations of the impurity and by a canonical transformation. On the level of
dynamical mean-field theory this establishes the connection of the two lattice
models. The impurity model is studied numerically by an extension of the
non-crossing approximation to a two-orbital impurity. We find that with
decreasing temperature the conduction electrons first form quasiparticles
unaffected by the presence of the lattice of localized spins. Then, reducing
the temperature further, the particle-hole symmetric model turns into an
insulator. The quasiparticle peak in the one-particle spectral density splits
and a gap opens. The size of the gap increases when the correlations of the
conduction electrons become stronger. These findings are similar to the
behavior of the Anderson-Hubbard model within dynamical mean-field theory and
are obtained with much less numerical effort.Comment: 7 pages RevTeX with 3 ps figures, accepted by PR
Research utility of noninvasive methods for measurement of cardiac output
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109853/1/cptclpt198751.pd
Contact-mediated nucleation in melt emulsions investigated by rheo-nuclear magnetic resonance
Increasing the efficiency of disperse phase crystallization is of great interest for melt emulsion production as the fraction of solidified droplets determines product quality and stability. Nucleation events must appear within every single one of the μm-sized droplets for solidification. Therefore, primary crystallization requires high subcooling and is, thus, time and energy consuming. Contact-mediated nucleation is a mechanism for intensifying the crystallization process. It is defined as the successful nucleation of a subcooled liquid droplet induced by contact with an already crystallized droplet. We investigated contact-mediated nucleation under shear flow conditions up to shear rates of 457 s for a quantitative assessment of this mechanism. Rheo-nuclear magnetic resonance was successfully used for the time-resolved determination of the solids fraction of the dispersed phase of melt emulsions upon contact-mediated nucleation events. The measurements were carried out in a dedicated Taylor–Couette cell. The efficiency of contact-mediated nucleation decreased with increasing shear rate, whereas the effective second order kinetic constant k increased approximately linearly at small shear rates and showed a linear decrease for shear rates higher than about 200 s. These findings are in accordance with coalescence theory. Thus, the nucleation rate is optimal at specific flow conditions. There are limitations for successful inoculation at a low shear rate because of rare contact events and at a high shear rate due to too short contact time
A Bayesian model for longitudinal count data with non-ignorable dropout
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73907/1/j.1467-9876.2008.00628.x.pd
On Linear Differential Equations Involving a Para-Grassmann Variable
As a first step towards a theory of differential equations involving para-Grassmann variables the linear equations with constant coefficients are discussed and solutions for equations of low order are given explicitly. A connection to n-generalized Fibonacci numbers is established. Several other classes of differential equations (systems of first order, equations with variable coefficients, nonlinear equations) are also considered and the analogies or differences to the usual (''bosonic'') differential equations discussed
Magnetic impurity coupled to interacting conduction electrons
We consider a magnetic impurity which interacts by hybridization with a
system of weakly correlated electrons and determine the energy of the ground
state by means of an 1/N_f expansion. The correlations among the conduction
electrons are described by a Hubbard Hamiltonian and are treated to lowest
order in the interaction strength. We find that their effect on the Kondo
temperature, T_K, in the Kondo limit is twofold: First, the position of the
impurity level is shifted due to the reduction of charge fluctuations, which
reduces T_K. Secondly, the bare Kondo exchange coupling is enhanced as spin
fluctuations are enlarged. In total, T_K increases. Both corrections require
intermediate states beyond the standard Varma-Yafet ansatz. This shows that the
Hubbard interaction does not just provide quasiparticles, which hybridize with
the impurity, but also renormalizes the Kondo coupling.Comment: ReVTeX 19 pages, 3 uuenconded postscript figure
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