3,006 research outputs found
Scholarship of Teaching and Learning: Developing a Culture of Assessment
The Scholarship of Teaching and Learning Initiative at Hostos Community College focuses on melding assessment and faculty development through a scholastic approach. In order to facilitate a campus-wide engagement in assessment, particularly related to the effectiveness of classroom instruction, the focus remains on individual expectations and talents, professional responsibilities, and using formative and summative assessment to improve student success and recidivism. This was initiated through open dialogue on the critical need for inquiry-based instruction, targeted presentations, and a sustainable network of support
Biologie de BOVICOLA LIMBATA (Mallophaga). Utilisation de milieux artificiels pour l'élevage au laboratoire. Influence du poil de l'hôte sur l'oviposition et l'évolution larvaire
Multifunctional Eu-doped NaGd(MoO4)(2) nanoparticles functionalized with poly(L-lysine) for optical and MRI imaging
A method for the synthesis of non-aggregated and highly uniform Eu3+ doped NaGd(MoO4)(2) nanoparticles is reported for the first time. The obtained particles present tetragonal structure, ellipsoidal shape and their size can be varied by adjusting the experimental synthesis parameters. These nanoparticles, which were coated with citrate anions and functionalised with PLL, have also been developed in order to improve their colloidal stability in physiological medium (2-(N-morpholino) ethanesulfonic acid, MES). A study of the luminescent dynamics of the samples as a function of the Eu doping level has been conducted in order to find the optimum nanophosphors, whose magnetic relaxivity and cell viability have also been evaluated for the first time for this system, in order to assess their suitability as multifunctional probes for optical (in vitro) and magnetic bioimaging applications
INTEGRAL-RXTE observations of Cygnus X-1
We present first results from contemporaneous observations of Cygnus X-1 with
INTEGRAL and RXTE, made during INTEGRAL's performance verification phase in
2002 November and December. Consistent with earlier results, the 3-250 keV data
are well described by Comptonization spectra from a Compton corona with a
temperature of kT~50-90 keV and an optical depth of tau~1.0-1.3 plus reflection
from a cold or mildly ionized slab with a covering factor of Omega/2pi~0.2-0.3.
A soft excess below 10 keV, interpreted as emission from the accretion disk, is
seen to decrease during the 1.5 months spanned by our observations. Our results
indicate a remarkable consistency among the independently calibrated detectors,
with the remaining issues being mainly related to the flux calibration of
INTEGRAL.Comment: 6 pages, 3 figures. Figs. 2 and 3 are best viewed in color. Accepted
for publication in the INTEGRAL special edition of A&A
Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study
Introduction Consensus criteria for pediatric severe sepsis have standardized enrollment for research studies. However, the extent to which critically ill children identified by consensus criteria reflect physician diagnosis of severe sepsis, which underlies external validity for pediatric sepsis research, is not known. We sought to determine the agreement between physician diagnosis and consensus criteria to identify pediatric patients with severe sepsis across a network of international pediatric intensive care units (PICUs). Methods We conducted a point prevalence study involving 128 PICUs in 26 countries across 6 continents. Over the course of 5 study days, 6925 PICU patients \u3c18 years of age were screened, and 706 with severe sepsis defined either by physician diagnosis or on the basis of 2005 International Pediatric Sepsis Consensus Conference consensus criteria were enrolled. The primary endpoint was agreement of pediatric severe sepsis between physician diagnosis and consensus criteria as measured using Cohen’s κ. Secondary endpoints included characteristics and clinical outcomes for patients identified using physician diagnosis versus consensus criteria. Results Of the 706 patients, 301 (42.6 %) met both definitions. The inter-rater agreement (κ ± SE) between physician diagnosis and consensus criteria was 0.57 ± 0.02. Of the 438 patients with a physician’s diagnosis of severe sepsis, only 69 % (301 of 438) would have been eligible to participate in a clinical trial of pediatric severe sepsis that enrolled patients based on consensus criteria. Patients with physician-diagnosed severe sepsis who did not meet consensus criteria were younger and had lower severity of illness and lower PICU mortality than those meeting consensus criteria or both definitions. After controlling for age, severity of illness, number of comorbid conditions, and treatment in developed versus resource-limited regions, patients identified with severe sepsis by physician diagnosis alone or by consensus criteria alone did not have PICU mortality significantly different from that of patients identified by both physician diagnosis and consensus criteria. Conclusions Physician diagnosis of pediatric severe sepsis achieved only moderate agreement with consensus criteria, with physicians diagnosing severe sepsis more broadly. Consequently, the results of a research study based on consensus criteria may have limited generalizability to nearly one-third of PICU patients diagnosed with severe sepsis
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