Tuning gastropod locomotion: Modeling the influence of mucus rheology on the cost of crawling

Common gastropods such as snails crawl on a solid substrate by propagating muscular waves of shear stress on a viscoelastic mucus. Producing the mucus accounts for the largest component in the gastropod's energy budget, more than twenty times the amount of mechanical work used in crawling. Using a simple mechanical model, we show that the shear-thinning properties of the mucus favor a decrease in the amount of mucus necessary for crawling, thereby decreasing the overall energetic cost of locomotion.Comment: Corrected typo

Perancangan Kampanye Safety Riding untuk Pengendara Motor Surabaya 2012

Bertambahnya jumlah sepeda motor di Surabaya yang demikian pesat tiap tahunnya, membuat angka pelanggaran lalu lintas cukup tinggi. Dengan jumlah sepeda motor yang banyak, mengakibatkan jumlah pelanggaran naik, yang berimbas pada tingginya angka kecelakaan di Surabaya. Pelanggaran lalu lintas ini cenderung mengalami kenaikan tiap tahunnya.Tingkat kepedulian pengendara motor masih sangat rendah untuk melakukan disiplin lalu lintas. Dibutuhkan kampanye safety riding yang merupakan salah satu solusi yang dapat dilakukan untuk menangani hal tersebut. Perancangan kampanye ini menggunakan metode penelitian deskriptif dengan instrument pengumpulan data menggunakan kuesioner, wawancara mendalam, serta pengamatan pada pengguna kendaraan bermotor di Surabaya.Dengan menggunakan metode perancangan diatas, dapat dilihat bahwa permasalahan lalu lintas di Surabaya dapat diatasi salah satu satunya dengan kampanye safety riding yang menggunakan media yang menarik dan efektif untuk memaksimalkan hasil kampanye. Media yang menarik dan efektif ini disesuaikan dengan apa yang responden suka sehingga kampanye akan tepat sasara

Analisis Hira (Hazard Identification and Risk Assessment) Pada Industri Tahu Serasi Bandungan Baru Semarang

HIRA is one of many risk valuation methods that can be used to value which hazard is able to provoke the biggest risk. Its done by considering the probability and the impact. Tahu Serasi Bandungan Baru Industri is one of many informal sector industries having hazard potential to the work environment and work process. This researchs purpose is to identify hazard potential, risk assessment , describe current hazard control and recommend hazard control means to decrease work accident risk. This research is done in two location of Tahu Serasi Bandungan Baru production by using explanatory research with 14 respondents which consist of 12 main informant and 2 triangulation informant. In detail, each location has 6 main informant and 1 triangulation informant. Work process in this tofu industri is divided into two, odd section and milling section. Based on research some hazard potentials are learned. Those are cramp, slip, process tools wedge, process tools struck down, mold, hot soybean extract, combustion fumes, electric shock, noise and fire. Tahu Serasi Bandungan Baru Industri has done some hazard control means by giving break time and personal protective equipment to employees

DNA and the chromosome – varied targets for chemotherapy

The nucleus of the cell serves to maintain, regulate, and replicate the critical genetic information encoded by the genome. Genomic DNA is highly associated with proteins that enable simple nuclear structures such as nucleosomes to form higher-order organisation such as chromatin fibres. The temporal association of regulatory proteins with DNA creates a dynamic environment capable of quickly responding to cellular requirements and distress. The response is often mediated through alterations in the chromatin structure, resulting in changed accessibility of specific DNA sequences that are then recognized by specific proteins. Anti-cancer drugs that target cellular DNA have been used clinically for over four decades, but it is only recently that nuclease specific drugs have been developed to not only target the DNA but also other components of the nuclear structure and its regulation. In this review, we discuss some of the new drugs aimed at primary DNA sequences, DNA secondary structures, and associated proteins, keeping in mind that these agents are not only important from a clinical perspective but also as tools for understanding the nuclear environment in normal and cancer cells

Decolonising indigenous social impact research using community-based methods

© 2019 Association of Researchers in Construction Management, ARCOM 2019 - Proceedings of the 35th Annual Conference. All rights reserved. Indigenous procurement policies encourage the construction sector to provide new training, employment and business opportunities for Indigenous people suffering from economic and social disadvantage. However, the success of these policies is often distorted by the failure of policy evaluations to account for Indigenous perceptions of social value. Since these often differ markedly from non-Indigenous values, this can distort the allocation of funds to Indigenous communities and exacerbate the marginalisation of the communities these policies are meant to help. Drawing on theories of community-based research, this methodological paper seeks to reconceptualise approaches to measuring Indigenous social value in an Indigenous social procurement policy context. Working in partnership with a peak body for Aboriginal business in Australia, we have co-designed a novel approach to Indigenous social impact research that recognises the legitimacy of Indigenous perspectives when investigating the social value Indigenous procurement policies create. We argue that culturally appropriate focus groups (yarning discussion groups) are appropriate in Indigenous social impact research because they prioritise Indigenous people's experiences of Indigenous procurement policies, rather than focusing on simplistic policy targets. As a method that promotes community involvement in social impact research to define how social value is perceived, yarning discussion groups have significant implications for future research seeking to represent Indigeonus perspectives of social value. It is concluded the approach developed here can be operationalised in the field to better understand the nature of Indigenous social value and the impact created by Indigenous procurement policies in Australia and other countries with disadvantaged Indigenous populations

Quaternary faulting in the New Madrid seismic zone in southernmost Illinois

U.S. Geological Survey, Department of the Interior, National Earthquake Hazards Reduction Program Award No. 1434-95-G-2525Ope

Addressing Disparities in Acute Stroke Management and Prognosis

There are now abundant data demonstrating disparities in acute stroke management and prognosis; however, interventions to reduce these disparities remain limited. This special report aims to provide a critical review of the current landscape of disparities in acute stroke care and highlight opportunities to use implementation science to reduce disparities throughout the early care continuum. In the prehospital setting, stroke symptom recognition campaigns that have been successful in reducing prehospital delays used a multilevel approach to education, including mass media, culturally tailored community education, and professional education. The mobile stroke unit is an organizational intervention that has the potential to provide more equitable access to timely thrombolysis and thrombectomy treatments. In the hospital setting, interventions to address implicit biases among health care providers in acute stroke care decision‐making are urgently needed as part of a multifaceted approach to advance stroke equity. Implementing stroke systems of care interventions, such as evidence‐based stroke care protocols at designated stroke centers, can have a broader public health impact and may help reduce geographic, racial, and ethnic disparities in stroke care, although further research is needed. The long‐term impact of disparities in acute stroke care cannot be underestimated. The consistent trend of longer time to treatment for Black and Hispanic people experiencing stroke has direct implications on long‐term disability and independence after stroke. A learning health system model may help expedite the translation of evidence‐based interventions into clinical practice to reduce disparities in stroke care

Artificial intelligence, bias and clinical safety

This is the final version. Available on open access from BMJ Publishing group via the DOI in this recordEngineering and Physical Sciences Research Council (EPSRC

Quaternary faulting in the New Madrid seismic zone in southernmost Illinois

U.S. Geological Survey, Department of the Interior, under USGS award number 1434-95-G-2525Ope