525 research outputs found
Effect of aggregation on chromophore structure in allophycocyanin studied by resonance CARS-spectroscopy
Combining Membrane and Zero Brine Technologies in Waste Acid Treatment for a Circular Economy in the HotâDip Galvanizing Industry: A Life Cycle Perspective
An innovative approach of combining membrane and zero brine technologies for a joint treatment of industrial liquid waste
is investigated regarding its environmental impacts compared to the existing liquid waste treatment. The object of investigation is the generation of waste acid solution by a hot dip galvanizing plant in Sicily, Italy. The waste acid solution contains
hydrochloric acid, iron and zinc, which makes it a hazardous waste according to EU classifcations. Environmental impacts
are studied for two scenarios in the Tecnozinco hot-dip galvanizing plant in Sicily, Italy: (i) the current process of pickling
with linear disposal of waste acid and (ii) the pickling combined with in-situ treatment of the waste acid using a combination
of difusion dialysis (DD), membrane distillation (MD) and a precipitation reactor. Results are obtained via an attributional
life cycle assessment (LCA) approach focusing on the water footprint profle of the process. The linear disposal path creates
signifcant costs, environmental burdens and risks during the 1500 km transport of hazardous liquid waste. The combination
of DD and MD, complemented with a zero-brine precipitation reactor, closes internal material loops, could save local water
resources and reduces costs as well as environmental impacts. Reduction potentials of 70â80% regarding most LCA impact
categories can be expected for the application of the novel technology combination supporting the galvanizing pre-treatment
process under study. Therefore, the application of such technology on the way forward to a more circular economy is recommended from an environmental viewpoint, especially in process plants similar to the investigated one
Effect of aging on esophageal motility in patients with and without GERD
Background/Aims: The impact of aging on esophageal motility is not completely understood. This study aims at assessing 1) whether degeneration of esophageal body motility occurs with age and 2) whether this development is influenced by gastroesophageal reflux disease (GERD)
Effect of aging on esophageal motility in patients with and without GERD
Background/Aims: The impact of aging on esophageal motility is not completely understood. This study aims at assessing 1) whether degeneration of esophageal body motility occurs with age and 2) whether this development is influenced by gastroesophageal reflux disease (GERD)
Soziale Bedingungen von Schulleistungen: Zur Erfassung von Kontextmerkmalen durch SchĂŒler-, Schul- und Elternfragebögen [Elektronische Ressource]
Author's comment: sine ann
Outreach initiatives operated by universities for increasing interest in science and technology
This is an Accepted Manuscript of an article published by Taylor & Francis in European Journal of Engineering Edutaion on 2016, available online: http://www.tandfonline.com/10.1080/03043797.2015.1121468Since the 1990s, the low number of students choosing to study science
and technology in higher education has been on the societal agenda
and many initiatives have been launched to promote awareness
regarding career options. The initiatives particularly focus on increasing
enrolment in the engineering programmes. This article describes and
compares eight European initiatives that have been established and
operated by universities (and in some cases through collaboration with
other actors in society). Each initiative is summarised in a short essay
that discusses motivation, organisation, pedagogical approach, and
activities. The initiatives are characterised by comparing the driving
forces behind their creation, how the initiative activities relate to the
activities at the university, size based on the number of participants and
cost per participant and pedagogical framework. There seem to be two
main tracks for building outreach activities, one where outreach
activities are based on the universityâs normal activities, and one where
outreach activities are designed specifically for the visiting students.Gumaelius, L.; Almqvistb, M.; Arnadottir, A.; Axelsson, A.; Conejero, JA.; GarcĂa Sabater, JP.; Klitgaard, L.... (2016). Outreach initiatives operated by universities for increasing interest in science and technology. European Journal of Engineering Education. 41(6):589-622. https://doi.org/10.1080/03043797.2015.1121468S58962241
Das virtuelle Software-Engineering-Kompetenzzentrum (ViSEK)
Software-Engineering ist eine wichtige Produktivtechnik fĂŒr das 21. Jahrhunderts, weil Software in zunehmend mehr Branchen Anwendung findet und maĂgeblich die Leistungs- und WettbewerbsfĂ€higkeit einer Vielzahl von Produkten beeinflusst. Vor diesem Hintergrund vernetzt das virtuelle Software-Engineering-Kompetenzzentrum (ViSEK) Software-Professionals aus Forschung und Industrie und bietet insbesondere kleinen und mittelstĂ€ndigen Unternehmen (KMUs) einen umfassenden Wissenspool von Technologie-Beschreibungen und Erfahrungen. Ausgehend von sozio-kulturellen Lerntheorien unterstĂŒtzt ViSEK den Aufbau von Lerngemeinschaften zwischen Software-Professionals auf drei verschiedenen Ebenen (a) zwischen fĂŒhrenden nationalen Forschungsgruppen, (b) zwischen Forschungsgruppen und Praktikern und (c) zwischen Praktikern. Zwei AnsĂ€tze fĂŒr den Aufbau von Lerngemeinschaften beschreiben wir detaillierter (a) ein Internet Portal, welches Software-Engineering Wissen darstellt und FunktionalitĂ€t fĂŒr die UnterstĂŒtzung von Gemeinschaftsbildung bietet, (b) regionale Netzwerke die Erfahrungsaustausch und Lernen in bestimmten Feldern des Software-Engineerings unterstĂŒtzen
Ion energy distribution functions behind the sheaths of magnetized and non magnetized radio frequency discharges
The effect of a magnetic field on the characteristics of capacitively coupled
radio frequency discharges is investigated and found to be substantial. A
one-dimensional particle-in-cell simulation shows that geometrically symmetric
discharges can be asymmetrized by applying a spatially inhomogeneous magnetic
field. This effect is similar to the recently discovered electrical asymmetry
effect. Both effects act independently, they can work in the same direction or
compensate each other. Also the ion energy distribution functions at the
electrodes are strongly affected by the magnetic field, although only
indirectly. The field influences not the dynamics of the sheath itself but
rather its operating conditions, i.e., the ion flux through it and voltage drop
across it. To support this interpretation, the particle-in-cell results are
compared with the outcome of the recently proposed ensemble-in-spacetime
algorithm. Although that scheme resolves only the sheath and neglects
magnetization, it is able to reproduce the ion energy distribution functions
with very good accuracy, regardless of whether the discharge is magnetized or
not
UTP and ATP increase extracellular signal-regulated kinase 1/2 phosphorylation in bovine chromaffin cells through epidermal growth factor receptor transactivation
Adenosine triphosphate (ATP) is coreleased with catecholamines from adrenal medullary chromaffin cells in response to sympathetic nervous system stimulation and may regulate these cells in an autocrine or paracrine manner. Increases in extracellular signal-regulated kinase (ERK) 1/2 phosphorylation were observed in response to ATP stimulation of bovine chromaffin cells. The signaling pathway involved in ATP-mediated ERK1/2 phosphorylation was investigated via Western blot analysis. ATP and uridine 5âČ-triphosphate (UTP) increased ERK1/2 phosphorylation potently, peaking between 5 and 15 min. The mitogen-activated protein kinase (MAPK/ERK)-activating kinase (MEK) inhibitor PD98059 blocked this response. UTP, which is selective for G-protein-coupled P2Y receptors, was the most potent agonist among several nucleotides tested. Adenosine 5âČ-O-(3-thio) triphosphate (ATPÎłS) and ATP were also potent agonists, characteristic of the P2Y2 or P2Y4 receptor subtypes, whereas agonists selective for P2X receptors or other P2Y receptor subtypes were weakly effective. The receptor involved was further characterized by the nonspecific P2 antagonists suramin and reactive blue 2, which each partially inhibited ATP-mediated ERK1/2 phosphorylation. Inhibitors of protein kinase C (PKC), protein kinase A (PKA), Ca2+/calmodulin-dependent protein kinase II (CaMKII), and phosphoinositide-3 kinase (PI3K) had no effect on ATP-mediated ERK1/2 phosphorylation. The Src inhibitor PP2, epidermal growth factor receptor (EGFR) inhibitor AG1478, and metalloproteinase inhibitor GM6001 decreased ATP-mediated ERK1/2 phosphorylation. These results suggest nucleotide-mediated ERK1/2 phosphorylation is mediated by a P2Y2 or P2Y4 receptor, which stimulates metalloproteinase-dependent transactivation of the EGFR
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