Can we use GPS for assessing sprinting performance in rugby sevens? A concurrent validity and between-device reliability study

Purpose: The purpose of this study was to (1) provide data on maximal sprinting speed (MSS) and maximal acceleration (Amax) in elite rugby sevens players measured with GPS devices, (2) test the concurrent validity of the signal derived from a radar device and a commercially available 16 Hz GPS device, and (2) assess the between-device reliability of MSS and Amax of the same GPS. Methods: Five well-trained rugby players participated. A concurrent validity protocol compared the GPS units and a radar device (Stalker ATS II). The between-device reliability of the GPS signal during maximal sprint running was also assessed using 6 V2 GPS units (Sensoreverywhere, Digital Simulation, Paris, France) attached to a custom-made steel sled and pushed by one athlete who performed 15 linear 40m sprints. Results: CV ranged from 0.5, ±0.1 % for MSS and smoothed MSS to 6.4, ±1.1 % for Amax. TEM was trivial for MSS and smoothed MSS (0.09, ±0.01) and small for Amax and smoothed Amax (0.54, ±0.09 and 0.39, ±0.06 respectively). Mean bias ranged from -1.6, ±1.0% to -3.0, ±1.1 % for smoothed MSS and MSS respectively. TEE were small (2.0, ±0.55 to 1.6, ±0.4%, for MSS and smoothed MSS respectively. Discussion: The main results indicate that the GPS units were highly reliable for assessing MSS and provided acceptable signal to noise ratio for measuring Amax, especially when a smoothing 0.5-s moving average is used. This 16 Hz GPS device provides sport scientists and coaches with an accurate and reliable means to monitor running performance in elite rugby sevens

Workload, fatigue and muscle damage in an U20 rugby union team over an intensified international tournament

Purpose: This study examined the effects of an intensified tournament on workload, perceptual and neuromuscular fatigue and muscle damage responses in an international under-20 rugby union team. Methods: Players were subdivided into two groups according to match-play exposure time: high (HEG, n=13) and low (LEG, n=11). Measures monitored over the 19-day period included training session (n=10) and match (n=5) workload determined via global positioning systems and session ratings of perceived exertion (sRPE). Wellbeing scores, countermovement jump height performance (CMJ) and blood creatine kinase [CK]b concentrations were collected at various time points. Results: Analysis of workload cumulated across the tournament entirety for training and match-play combined showed that high-speed running distance was similar between groups while a very likely larger sRPE load was reported in HEG vs. LEG. In HEG high-speed activity fluctuated across the 5 successive matches albeit with no clear trend for a progressive decrease. No clear tendency for a progressive decrease in wellbeing scores prior to or following matches was observed in either group. In HEG trivial to possibly small reductions in post-match CMJ performance were observed while unclear to most likely moderate increases in pre-match [CK]b concentrations occurred until prior to match 4. Conclusion: The magnitude of match-to-match changes in external workload, perceptual and neuromuscular fatigue and muscle damage was generally unclear or small. These results suggest that irrespective of exposure time to match-play players generally maintained performance and readiness to play across the intensified tournament. These findings support the need for holistic systematic player monitoring programmes

Endovascular Stent Grafts as a Safe Secondary Option for Paraanastomotic Abdominal Aortic Aneurysm

ObjectiveTo describe our experience of endovascular repair of paraanastomotic aortic aneurysm.Methods and resultsFrom March 2001 to December 2004 we identified 6 patients with a paraanastomotic aortic aneurysms following previous open repair of abdominal aortic aneurysm. All patients were treated with endovascular surgery under epidural anaesthesia. There were no major complications, surgical conversions or deaths. Four patients received a bifurcated aortic stent-graft, and two an aorto-uniliac stent-graft followed by a femoro-femoral bypass. At follow-up (mean 26.1±10.2 months) there were no deaths, endoleaks or graft migrations observed.ConclusionEndovascular surgery, avoiding general anesthesia and re-laparotomy, is the ideal technique for treatment of this complication resulting from failed primary conventional AAA repair

Endovascular Stent Grafts as a Safe Secondary Option for Paraanastomotic Abdominal Aortic Aneurysm

Objective: To describe our experience of endovascular repair of paraanastomotic aortic aneurysm. Methods and results: From March 2001 to December 2004 we identified 6 patients with a paraanastomotic aortic aneurysms following previous open repair of abdominal aortic aneurysm. All patients were treated with endovascular surgery under epidural anaesthesia. There were no major complications, surgical conversions or deaths. Four patients received a bifurcated aortic stent-graft, and two an aorto-uniliac stent-graft followed by a femoro-femoral bypass. At follow-up (mean 26.1 ± 10.2 months) there were no deaths, endoleaks or graft migrations observed. Conclusion: Endovascular surgery, avoiding general anesthesia and re-laparotomy, is the ideal technique for treatment of this complication resulting from failed primary conventional AAA repair. © 2006 Elsevier Ltd. All rights reserved

In-match physical performance fluctuations in international rugby sevens competition

It is widely recognised that the physical demands in rugby sevens are high especially in comparison to the 15-aside version. The aim of this study was to assess fluctuations in physical performance (running and contact loads) in international rugby sevens competition. Altogether, 32 matches played by an international team in the HSBC World Sevens Series were analyzed (63 match-observations). Players wore a validated GPS device (SensorEverywhere, France) sampling at 16Hz while an operator coded every contact action (tackles, collisions, mauls, scrums) using video analysis software (SportsCode, USA). Running load was assessed using total distance travelled (m), individually determined high-speed distance (covered at velocities > maximal aerobic speed, m) and very-high speed distance (covered at velocities > 85% maximal sprinting speed, m). The frequency of accelerations (actions > 2.5 m.s-1) and high-intensity actions (HIA, sum of high-velocity runs, accelerations and contact-related actions, n) were also calculated. A magnitude-based inferential approach to statistics was adopted and effect sizes quantified. Findings showed: 1) a small decrease in high speed distance and number of accelerations performed during the second- versus the first-half of play suggesting a decline in running performance. (2) a moderately higher total distance and high-speed distance covered during the first and final 1-min period compared to the average for other 1-min periods, suggesting a specific reverse ‘J-shape’ pacing profile 3) a most likely decrease in total distance, high-speed running, and to a lesser extent the number of accelerations declined following the peak 1-min period of the game. These findings provide pertinent information on changes in running performance over the course of international sevens and have implications for physical conditioning strategies

Bivalirudin in patients undergoing pci: state of art and future perspectives

Acute coronary syndrome (ACS) represents the most common cause of death worldwide. Percutaneous coronary intervention (PCI) is the management of choice in patients with ACS and occurrence of intra procedural thrombotic complications are an independent predictor of mortality and other major adverse cardiovascular events in patients undergoing PCI. According to current guideline, anticoagulation therapy is indicated during PCI in order to reduce the risk of thrombotic complications such as stent thrombosis. Among currently available anticoagulant drugs, bivalirudin demonstrates a lower incidence of bleeding risk, despite it is associated with an increased risk of stent thrombosis. The aim of this paper is to discuss the pharmacology of bivalirudin and the clinical evidences of its use in patients undergoing PCI for ACS

Sirt1 activity in pbmcs as a biomarker of different heart failure phenotypes

Heart Failure (HF) is a syndrome, which implies the existence of different phenotypes. The new categorization includes patients with preserved ejection fraction (HFpEF), mid-range EF (HFmrEF), and reduced EF (HFrEF) but the molecular mechanisms involved in these HF phenotypes have not yet been exhaustively investigated. Sirt1 plays a crucial role in biological processes strongly related to HF. This study aimed to evaluate whether Sirt1 activity was correlated with EF and other parameters in HFpEF, HFmrEF, and HFrEF. Seventy patients, HFpEF (n = 23), HFmrEF (n = 23) and HFrEF (n = 24), were enrolled at the Cardiology Unit of the University Hospital of Salerno. Sirt1 activity was measured in peripheral blood mononuclear cells (PBMCs). Angiotensin-Converting Enzyme 2 (ACE2) activity, Tumor Necrosis Factor-alpha (TNF-α) and Brain Natriuretic Peptide (BNP) levels were quantified in plasma. HFpEF showed lower Sirt1 and ACE2 activities than both HFmrEF and HFrEF (p < 0.0001), without difference compared to No HF controls. In HFmrEF and HFrEF a very strong correlation was found between Sirt1 activity and EF (r2 = 0.899 and r2 = 0.909, respectively), and between ACE2 activity and Sirt1 (r2 = 0.801 and r2 = 0.802, respectively). HFrEF showed the highest TNF-α levels without reaching statistical significance. Significant differences in BNP were found among the groups, with the highest levels in the HFrEF. Determining Sirt1 activity in PBMCs is useful to distinguish the HF patients’ phenotypes from each other, especially HFmrEF/HFrEF from HFpEF

The travel demands of an elite rugby sevens team: Effects on objective and subjective sleep parameters

Purpose: To explore the effects of travel related to international rugby sevens competition on sleep patterns. Methods: Seventeen international male rugby sevens players participated in this study. Sleep assessments were performed daily during two separate Sevens World Series competition legs (Oceania and America). The duration of each competition leg was subdivided into key periods (pre-tour, pre-competition, tournament 1 and 2, relocation and post-tour) lasting 2 to 7 nights. Linear mixed models in combination with magnitude-based decision were used to assess 1) the difference between pre-season and key periods and 2) the effect of travel direction (eastward or westward). Results: Shorter total sleep time (hh:mm) was observed during tournament 2 (mean ± SD, 06:16 ± 01:08), relocation (06:09 ± 01:09) and pre-tour week (06:34 ± 01:24) compared with pre-season (06:52 ± 01:00). Worse sleep quality (AU) was observed during tournament 1 (6.1 ± 65 2.0) and 2 (5.7 ± 1.2) as well as during the relocation week (6.3 ± 1.5) than during pre-season (6.5 ± 1.8). When traveling eastward compared with westward, earlier fall asleep time was observed during tournament 1 (ES -0.57, 90%CI [-1.12 to -0.01]), relocation week (-0.70 [-1.11 to -0.28]), and post-tour (-0.57 [-0.95 to -0.18]). However, possibly trivial and unclear differences were observed during pre-competition week (0.15 [-0.15 to 0.45]) and tournament 2 (0.81 [-0.29 to 1.91]). Conclusion: Sleep patterns of elite rugby sevens players are robust to the effects of long-haul travel and jet lag. However, staff should consider promoting sleep during the tournament and 73 relocation week