An AFM Approach of RBC Micro and Nanoscale Topographic Features During Storage

Blood gamma irradiation is the only available method to prevent transfusion-associated graft versus host disease (TA-GVHD). However, when blood is irradiated, determine blood shelf time is crucial. Non-irradiated blood has a self-time from 21 to 35 days when is preserved with an anticoagulated solution and stored at 4°C. During their storage, red blood cells (RBC) undergo a series of biochemical, biomechanical and molecular changes involving what is known as storage lesion (SL). SL include loss of structural integrity of RBC, a decrease of 2,3-diphosphatidylglyceric acid levels, and an increase of both ion potassium concentration and hemoglobin (Hb). On the other hand, Atomic force Microscopy (AFM) represents a versatile tool for a nano-scale high-resolution topographic analysis in biological systems. In order to evaluate SL in irradiated and non-irradiated blood, RBC topography and morphometric parameters were obtained from an AFM XE-BIO system. Cell viability was followed using flow cytometry. Our results showed that early markers as nanoscale roughness, allow us to evaluate blood quality since another perspective

Data for: Identification of inhalable rutile and polycyclic aromatic hydrocarbons (PAHs) nanoparticles in the atmospheric dust.

Analysis of road dust suggests that high rutile concentrations are deposited on the street and might be circulated in the air by wind, vehicle and pedestrian traffic. Atmospheric samples collected at pedestrian level are composed of a heterogeneous sample of micro and nanoparticles with a higher size range from 40 nm to 60 nm

Data for: Identification of inhalable rutile and polycyclic aromatic hydrocarbons (PAHs) nanoparticles in the atmospheric dust.

Analysis of road dust suggests that high rutile concentrations are deposited on the street and might be circulated in the air by wind, vehicle and pedestrian traffic. Atmospheric samples collected at pedestrian level are composed of a heterogeneous sample of micro and nanoparticles with a higher size range from 40 nm to 60 nm.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV

Thermoluminescence Properties of Undoped and Nitrogen-doped CVD Diamond Exposed to Gamma Radiation

It is known that the thermoluminescence (TL) performance of CVD diamond depends on the impurity concentration and doping materials introduced during growing. We report on the TL properites of undoped and 750 ppm nitrogen-doped CVD diamond grown on (100) silicon substrate. The samples were exposed to gamma radiation from a Gammacell 200 Nordion irradiator in the 10 - 500 Gy dose range at 627 mGy/min dose rate. The nitrogen-doped CVD diamond sample exhibit a TL glow curvge peaked around 573 K and a small shoulder about 411 K and a linear dose behavior in the range 10-60 Gy dose range. In the contrast, the undoped specimen showed a 591 K peaked TL glow curve and linear dose response for 10 - 100 Gy doses. However, both samples displayed a non-linear dose response for doses higher than 100 Gy. The doping effects seem to cause a higher TL efficiency, which may be attributed to the differences in the diamond bonding and amorphous carbon on the CVD samples as well as to the presence of nitrogen. In addition, the nitrogen content may produce some structural and morphological surface effects, which may account for the distinctive TL features and dose response of diamond samples.JRC.G.8-Nuclear safeguard

Dose Rate Effects on the Thermoluminescence Kinetics Properties of MWCVD Diamond Films

Dose rate effects are important in the thermoluminescencent (TL) dosimeter applications because a certain absorbed dose given at different dose rates may result in a different TL yeld. The present work reports about the dose rate effects on the TL glow curve and kinetics properties of microwave plasma assisted chemical vapor deposition (MWCVD) diamond films grown on (100) silicon. The diamond films were exposed to ¿ radiation at 20.67, 43.4 and 81.11 Gy min-1dose rates in the range of 0.05 ¿ 10 kGy. The films showed a linear dose behavior up to 2kGy and for higher dosesr.The TL intensity varied as a function of dose rate and the samples had a maximum TL response for lower dose rates. A single first order kinetics TL peak was typical for low doses and at higher doses two first order kinetics peaks were necessary to fit the glow curves. The results indicate that dose rate effects may be significant in dosimetric applications of MWCVD diamond.JRC.G.8-Nuclear safeguard

Release of nanoparticles in the environment and catalytic converters ageing

A Three-Way Catalyst (TWC) contains a cordierite ceramic monolith coated with a layer of Al2 O3, Cex Zr1−x O2 and platinoids mixture. Under standard operation, the platinoid concentration decreases, exposing the remaining washcoat structure. After that particle release stage, the sintering process follows where the crystalline Cex Zr1−x O2 solution is broken and begins to separate into ZrO2 and CeO2 phases. ZrO2 is released to the environment as micro and nanoparticles, while a small amount of CeO2 generates a new Alx Ce1−x O2 composite. The main effect of Ce capture is the growth in the size of the polycrystal structure from 86.13 ± 16.58 nm to 225.35 ± 69.51 nm. Moreover, a transformation of cordierite to mullite was identified by XRD analysis. Raman spectra showed that the oxygen vacancies (Vö) concentration decreased as Cex Zr1−x O2 phases separation occurred. The SEM-EDS revealed the incorporation of new spurious elements and microfractures favouring the detachment of the TWC support structure. The release of ultrafine particles is a consequence of catalytic devices overusing. The emission of refractory micro to nanocrystals to the atmosphere may represent an emerging public health issue underlining the importance of implementing strict worldwide regulations on regular TWCs replacement. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Temperature stimuli-responsive nanoparticles from chitosan-graft-poly(N-vinylcaprolactam) as a drug delivery system

This work describes the preparation of thermosensitive chitosan-graft-poly(N-vinylcaprolactam) nanoparticles by ionic gelation and their potential use as a controlled drug delivery system, using doxorubicin as a model drug. A systematic study of the effect of the main processing parameters on both the size and thermoresponsive behavior of nanoparticles was investigated. The size of the particles is strongly dependent on the length of the poly(N-vinylcaprolactam) grafted chains and the concentration of the copolymer and crosslinking agent solutions. The molecular structure of the copolymer plays an essential role in the phase transition temperature of the particles, which decreases with the length of PVCL grafted chain. The system displayed proper drug-association parameters, and the drug-loaded nanoparticles exhibited dose-dependent cytotoxicity. A significant increase in the doxorubicin delivery rate was observed above the phase transition temperature (40 °C). These features indicate that these nanoparticles are suitable for the development of a new thermally controlled anti-cancer drug delivery system. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47831.The authors acknowledge the Mexican Council of Science and Technology (CONACYT) for their financial support through the project PDCAPN-2014/248982. D.F.Q. acknowledges a grant from CONACYT (AIIVFPN-2017/291229). The authors are grateful for the technical support of Dr. Alvaro González-Gómez from ICTP-CSIC and M.C. Karla Martínez-Robinson, M.C. Luisa L. Silva, Q.B. Alma Campa-Mada, and Prof.Miguel A.Martínez-Tellez fromCIAD.Peer Reviewe