3,588 research outputs found
Exercise and hypertrophic cardiomyopathy: Two incompatible entities?
A greater understanding of the pathogenic mechanisms underpinning hypertrophic cardiomyopathy (HCM) has translated to improved medical care and better survival of affected individuals. Historically these patients were considered to be at high risk of sudden cardiac death (SCD) during exercise; therefore, exercise recommendations were highly conservative and promoted a sedentary life style. There is emerging evidence that suggests that exercise in HCM has a favorable effect on cardiovascular remodeling and moderate exercise programs have not raised any safety concerns. Furthermore, individuals with HCM have a similar burden of atherosclerotic risk factors as the general population in whom exercise has been associated with a reduction in myocardial infarction, stroke, and heart failure, especially among those with a high-risk burden. Small studies revealed that athletes who choose to continue with regular competition do not demonstrate adverse outcomes when compared to those who discontinue sport, and active individuals implanted with an implantable cardioverter defibrillator do not have an increased risk of appropriate shocks or other adverse events. The recently published exercise recommendations from the European Association for Preventative Cardiology account for more contemporary evidence and adopt a more liberal stance regarding competitive and high intensity sport in individuals with low-risk HCM. This review addresses the issue of exercise in individuals with HCM, and explores current evidence supporting safety of exercise in HCM, potential caveats, and areas of further research
Active Flow Control at Low Reynolds Numbers by Periodic Airfoil Morphing
This paper investigates the application of a periodically deforming airfoil surface for the purpose of flow control at low Reynolds numbers. A physical model has been fabricated by bonding Macro Fiber Composite (MFC) actuators to the underside of a NACA 4415âs suction surface. The results presented build on work by Jones et al.1 First, the behavior of the surface when actuated at a range frequencies is investigated through a combination of photogrammetric and laser sensor measurements. Second, the aerodynamic performance of this novel flow control technique is presented. It is shown that when the actuation frequency âlocks-inâ to the surface motion significant improvements in performance are observed in a flight regime notorious for poor airfoil behavior
Generating artificial light curves: Revisited and updated
The production of artificial light curves with known statistical and
variability properties is of great importance in astrophysics. Consolidating
the confidence levels during cross-correlation studies, understanding the
artefacts induced by sampling irregularities, establishing detection limits for
future observatories are just some of the applications of simulated data sets.
Currently, the widely used methodology of amplitude and phase randomisation is
able to produce artificial light curves which have a given underlying power
spectral density (PSD) but which are strictly Gaussian distributed. This
restriction is a significant limitation, since the majority of the light curves
e.g. active galactic nuclei, X-ray binaries, gamma-ray bursts show strong
deviations from Gaussianity exhibiting `burst-like' events in their light
curves yielding long-tailed probability distribution functions (PDFs). In this
study we propose a simple method which is able to precisely reproduce light
curves which match both the PSD and the PDF of either an observed light curve
or a theoretical model. The PDF can be representative of either the parent
distribution or the actual distribution of the observed data, depending on the
study to be conducted for a given source. The final artificial light curves
contain all of the statistical and variability properties of the observed
source or theoretical model i.e. same PDF and PSD, respectively. Within the
framework of Reproducible Research, the code, together with the illustrative
example used in this manuscript, are both made publicly available in the form
of an interactive Mathematica notebook.Comment: Accepted for publication in MNRAS. The paper is 23 pages long and
contains 21 figures and 2 tables. The Mathematica notebook can be found in
the web as part of this paper (Online Material) or at
http://www.astro.soton.ac.uk/~de1e08/ArtificialLightCurves
Measuring the broadband power spectra of active galactic nuclei with RXTE
We have developed a Monte Carlo technique to test models for the true power
spectra of intermittently sampled lightcurves against the noisy, observed power
spectra, and produce a reliable estimate of the goodness of fit of the given
model. We apply this technique to constrain the broadband power spectra of a
sample of four Seyfert galaxies monitored by the Rossi X-ray Timing Explorer
(RXTE) over three years. We show that the power spectra of three of the AGN in
our sample (MCG-6-30-15, NGC5506 and NGC3516) flatten significantly towards low
frequencies, while the power spectrum of NGC5548 shows no evidence of
flattening. We fit two models for the flattening, a `knee' model, analogous to
the low-frequency break seen in the power spectra of BHXRBs in the low state
(where the power-spectral slope flattens to \alpha=0) and a `high-frequency
break' model (where the power-spectral slope flattens to \alpha=1), analogous
to the high-frequency break seen in the high and low-state power spectra of the
classic BHXRB Cyg X-1. Both models provide good fits to the power spectra of
all four AGN. For both models, the characteristic frequency for flattening is
significantly higher in MCG-6-30-15 than in NGC 3516 (by factor ~10) although
both sources have similar X-ray luminosities, suggesting that MCG-6-30-15 has a
lower black hole mass and is accreting at a higher rate than NGC 3516. Assuming
linear scaling of characteristic frequencies with black hole mass, the high
accretion rate implied for MCG-6-30-15 favours the high-frequency break model
for this source and further suggests that MCG-6-30-15 and possibly NGC 5506,
may be analogues of Cyg X-1 in the high state [ABRIDGED].Comment: 23 pages, accepted for publication in MNRA
General relativistic modelling of the negative reverberation X-ray time delays in AGN
We present the first systematic physical modelling of the time-lag spectra
between the soft (0.3-1 keV) and the hard (1.5-4 keV) X-ray energy bands, as a
function of Fourier frequency, in a sample of 12 active galactic nuclei which
have been observed by XMM-Newton. We concentrate particularly on the negative
X-ray time-lags (typically seen above Hz) i.e. soft band variations
lag the hard band variations, and we assume that they are produced by
reprocessing and reflection by the accretion disc within a lamp-post X-ray
source geometry. We also assume that the response of the accretion disc, in the
soft X-ray bands, is adequately described by the response in the neutral iron
line (Fe k) at 6.4 keV for which we use fully general relativistic
ray-tracing simulations to determine its time evolution. These response
functions, and thus the corresponding time-lag spectra, yield much more
realistic results than the commonly-used, but erroneous, top-hat models.
Additionally we parametrize the positive part of the time-lag spectra
(typically seen below Hz) by a power-law. We find that the
best-fitting BH masses, M, agree quite well with those derived by other
methods, thus providing us with a new tool for BH mass determination. We find
no evidence for any correlation between M and the BH spin parameter, ,
the viewing angle, , or the height of the X-ray source above the disc,
. Also on average, the X-ray source lies only around 3.7 gravitational radii
above the accretion disc and the viewing angles are distributed uniformly
between 20 and 60 degrees. Finally, there is a tentative indication that the
distribution of spin parameters may be bimodal above and below 0.62.Comment: Accepted for publication in MNRAS. The paper is 22 pages long and
contains 19 figures and 2 table
X-ray and optical counterparts of hard X-ray selected sources from the SHEEP survey: first results
We present followup observations of five hard X-ray sources from the ASCA
5-10 keV SHEEP survey, which has a limiting flux of erg
cm s. Chandra data have been obtained to improve the X-ray
positions from a few arcmin to , which allows unambiguous optical
identification. While the objects almost certainly house AGN based on their
X-ray luminosity, optical spectroscopy reveals a variety of properties. The
identifications indicate that the SHEEP survey samples the same populations as
deeper surveys which probe the origin of the X-ray background, but because the
SHEEP sources are far brighter, they are more amenable to detailed followup
work. We find a variety of classifications and properties, including a type II
QSO, a galaxy undergoing star formation, and a broad-line AGN which has a very
hard X-ray spectrum, indicating substantial absorption in the X-ray but none in
the optical. Two objects have X-ray/optical flux ratios which, were they at an
X-ray flux level typical of objects in Chandra deep surveys, would place them
in the ``optically faint'' category. They are both identified with broad line
QSOs at z. Clearly this survey - which is relatively unbiased against
obscured objects - is revealing a set of remarkable objects quite different to
the familiar classes of AGN found in previous optical and soft X-ray surveys.Comment: 5 pages, 3 figures. MNRAS, in pres
Variability of the soft X-ray excess in IRAS 13224-3809
We study the soft excess variability of the narrow line Seyfert 1 galaxy IRAS
13224-3809. We considered all five archival XMM-Newton observations, and we
applied the 'flux-flux plot' (FFP) method. We found that the flux-flux plots
were highly affected by the choice of the light curves' time bin size, most
probably because of the fast and large amplitude variations, and the intrinsic
non-linear flux--flux relations in this source. Therefore, we recommend that
the smallest bin-size should be used in such cases. Hence, We constructed FFPs
in 11 energy bands below 1.7 keV, and we considered the 1.7-3 keV band, as
being representative of the primary emission. The FFPs are reasonably well
fitted by a 'power-law plus a constant' model. We detected significant positive
constants in three out of five observations. The best-fit slopes are flatter
than unity at energies below keV, where the soft excess is
strongest. This suggests the presence of intrinsic spectral variability. A
power-law-like primary component, which is variable in flux and spectral slope
(as ) and a soft-excess component, which varies
with the primary continuum (as ),
can broadly explain the FFPs. In fact, this can create positive `constants',
even when a stable spectral component does not exist. Nevertheless, the
possibility of a stable, soft--band constant component cannot be ruled out, but
its contribution to the observed 0.2-1 keV band flux should be less than %. The model constants in the FFPs were consistent with zero in one
observation, and negative at energies below 1 keV in another. It is hard to
explain these results in the context of any spectral variability scenario, but
they may signify the presence of a variable, warm absorber in the source.Comment: Accepted for publication in A&A, 10 pages, 7 figure
Discovery of multiple Lorentzian components in the X-ray timing properties of the Narrow Line Seyfert 1 Ark 564
We present a power spectral analysis of a 100 ksec XMM-Newton observation of
the narrow line Seyfert 1 galaxy Ark~564. When combined with earlier RXTE and
ASCA observations, these data produce a power spectrum covering seven decades
of frequency which is well described by a power law with two very clear breaks.
This shape is unlike the power spectra of almost all other AGN observed so far,
which have only one detected break, and resemble Galactic binary systems in a
soft state. The power spectrum can also be well described by the sum of two
Lorentzian-shaped components, the one at higher frequencies having a hard
spectrum, similar to those seen in Galactic binary systems. Previously we have
demonstrated that the lag of the hard band variations relative to the soft band
in Ark 564 is dependent on variability time-scale, as seen in Galactic binary
sources. Here we show that the time-scale dependence of the lags can be
described well using the same two-Lorentzian model which describes the power
spectrum, assuming that each Lorentzian component has a distinct time lag. Thus
all X-ray timing evidence points strongly to two discrete, localised, regions
as the origin of most of the variability. Similar behaviour is seen in Galactic
X-ray binary systems in most states other than the soft state, i.e. in the
low-hard and intermediate/very high states. Given the very high accretion rate
of Ark 564 the closest analogy is with the very high (intermediate) state
rather than the low-hard state. We therefore strengthen the comparison between
AGN and Galactic binary sources beyond previous studies by extending it to the
previously poorly studied very high accretion rate regime.Comment: 11 pages, 11 figures, accepted for publication in MNRA
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