41 research outputs found
Challenge-based learning as a practice for engineering education to develop students' entrepreneurial mindset
This paper aims to investigate the implications of Challenge Based Learning programs on entrepreneurial skills, mindset and intentions of university students using a quantitative approach. Using an original database, we analyzed pre and post levels of entrepreneurial skills, mindset and intention of 127 students who attended a Challenge Based Learning program. Results show a positive and significant effect of Challenge Based Learning programs on entrepreneurial mindset and skills â such as financial literacy, creativity and planning â of the students. Moreover, results show a positive but non-significative effect on entrepreneurial intention
Entrepreneurship education: the effects of challenge-based learning on the entrepreneurial mindset of university students
The aim of this paper is to investigate the implications of Challenge-Based Learning programs on entrepreneurial skills, and on the mindset and intentions of university students, through a quantitative approach. Resorting to an original database, we analyzed the pre-and post-levels of entrepreneurial skills, mindset and intention of 127 students who attended a Challenge-Based Learning program. Results show a positive and significant effect of Challenge-Based Learning programs on the entrepreneurial mindset and skillsâthat is, financial literacy, creativity, and planningâof the students
Toxicokinetics of perfluorooctane sulfonate in birds under environmentally realistic exposure conditions and development of a kinetic predictive model
Molecular Dynamics of Mesophilic-Like Mutants of a Cold-Adapted Enzyme: Insights into Distal Effects Induced by the Mutations
Networks and clusters of intramolecular interactions, as well as their âcommunicationâ across the three-dimensional architecture have a prominent role in determining protein stability and function. Special attention has been dedicated to their role in thermal adaptation. In the present contribution, seven previously experimentally characterized mutants of a cold-adapted α-amylase, featuring mesophilic-like behavior, have been investigated by multiple molecular dynamics simulations, essential dynamics and analyses of correlated motions and electrostatic interactions. Our data elucidate the molecular mechanisms underlying the ability of single and multiple mutations to globally modulate dynamic properties of the cold-adapted α-amylase, including both local and complex unpredictable distal effects. Our investigation also shows, in agreement with the experimental data, that the conversion of the cold-adapted enzyme in a warm-adapted variant cannot be completely achieved by the introduction of few mutations, also providing the rationale behind these effects. Moreover, pivotal residues, which are likely to mediate the effects induced by the mutations, have been identified from our analyses, as well as a group of suitable candidates for protein engineering. In fact, a subset of residues here identified (as an isoleucine, or networks of mesophilic-like salt bridges in the proximity of the catalytic site) should be considered, in experimental studies, to get a more efficient modification of the features of the cold-adapted enzyme
CONVERGENCE ANALYSIS FOR SIMULATIONS OF BIOMOLECULES
Professor of Chemistry and Biochemistr
Bolsas palpebrales inferiores y blefaroplastia estĂ©tica: investigaciĂłn anatomo-quirĂșrgica
Abordamos el estudio de las bolsas adiposas palpebrales inferiores contemplando la importancia de dos ejes fundamentales como son, en la prĂĄctica, la blefaroplastia estĂ©tica y el aspecto puramente anatĂłmico. Sobre material formolizado de la regiĂłn orbitaria y segĂșn tĂ©cnica habitual, practicamos disecciones en cada una de las preparaciones anatĂłmicas mediante las cuales fue posible estudiar, en la mitad inferior de la Ăłrbita, el comportamiento de la grasa y de las estructuras involucradas con ella permitiendo ademĂĄs incorporar la nociĂłn de la arquitectura del espacio retroseptal ĂĄntero-inferior y la de sus compartimentos o subdivisiones medial, central y lateral. Esta lĂnea de investigaciĂłn anatomo-quirĂșrgica condujo finalmente al preciso establecimiento de la ubicaciĂłn y de las principales caracterĂsticas de cada uno de los paquetes adiposos palpebrales inferiores
Setting up protocols for studying the proteome of a tyramine producing Enterococcus faecalis strain.
Il ruolo del crowdsourcing nel trasferimento tecnologico: una soluzione innovativa.
XII Rapporto Netval sulla Valorizzazione della Ricerca Pubblica Italian