534 research outputs found
The Department of Defense Patent Policy at the Cross Roads: An Argument for the Retention of Traditional Incentives
Barriers to the Uptake of Cataract Surgery and Eye Care After Community Outreach Screening in Takeo Province, Cambodia
Purpose:
To assess the barriers influencing eye healthcare seeking be-havior after community outreach screening. Design:
A concurrent mixed methods study. Methods:
A total of 469 patients screened during the previous 12 months were followed up, of which 354 (75%) from 5 districts were in-terviewed in person, using a semi-structured questionnaire, in-depth in-terviews (n = 11), and 16 focus groups (n = 71). SPSS and NVivo were used to analyze response frequency and identify themes. Results:
Of the respondents, 98% (350/354) reported they were told they had an eye problem, with 295 individuals (83%) told to attend CARITAS Takeo Eye Hospital (CTEH) and 55 to have their eyes checked at Kiri Vong Vision Centre. Of those 68.9% (244/354) who reported seeking treatment, only 7.4% (18/244) reported they attended CTEH, 54% (n = 132) attended a “local pharmacy,” 31.6% (n = 77) “self-treated at home,” 11% (n = 27) reported “using steam from boiling rice,” and 10.7% (n = 26) attended a “traditional healer.” Of those who reported reasons for “not attending,” responses included “no time” (47.8%, 86/180), “no one to accompany” (21.7%, n = 39), “fear of losing sight” (17.8%, n = 32), “cannot afford to travel” (16.1%, n = 29), and “eye problem is not serious enough” (15.6%, n = 28). Follow-up of patient records identified that 128 individuals (79 females) attended eye care services. Conclusions:
Socioeconomic factors, personal concerns, and the use of local cultural remedies were reasons for not seeking eye hospital treatment. An integrated community approach to improve awareness and uptake of appropriate treatment is recommended
Energetics and stability of nanostructured amorphous carbon
Monte Carlo simulations, supplemented by ab initio calculations, shed light
into the energetics and thermodynamic stability of nanostructured amorphous
carbon. The interaction of the embedded nanocrystals with the host amorphous
matrix is shown to determine in a large degree the stability and the relative
energy differences among carbon phases. Diamonds are stable structures in
matrices with sp^3 fraction over 60%. Schwarzites are stable in low-coordinated
networks. Other sp^2-bonded structures are metastable.Comment: 11 pages, 7 figure
Field-testing of the rapid assessment of disability questionnaire
The Rapid Assessment of Disability (RAD) questionnaire measures the magnitude and impact of disability and aims to inform the design of disability inclusive development programs. This paper reports the psychometric evaluation of the RAD
A Combination of Two Human Monoclonal Antibodies Limits Fetal Damage by Zika Virus in Macaques
Human infection by Zika virus (ZIKV) during pregnancy can lead to vertical transmission and fetal aberrations, including microcephaly. Prophylactic administration of antibodies can diminish or prevent ZIKV infection in animal models, but whether passive immunization can protect nonhuman primates and their fetuses during pregnancy has not been determined. Z004 and Z021 are neutralizing monoclonal antibodies to domain III of the envelope (EDIII) of ZIKV. Together the two antibodies protect nonpregnant macaques against infection even after Fc modifications to prevent antibody-dependent enhancement in vitro (ADE) and extend their half-lives. Here we report on prophylactic co-administration of the Fc-modified antibodies to pregnant rhesus macaques challenged 3 times with ZIKV during first and second trimester. The two antibodies did not entirely eliminate maternal viremia but limited vertical transmission protecting the fetus from neurologic damage. Thus, maternal passive immunization with two antibodies to EDIII can shield primate fetuses from the harmful effects of ZIKV
Female high heel shoes: a study of comfort
Protection was the basic principle underlying the creation of footwear, once
humankind felt the need to protect feet from direct contact with soil, heat, cold and sharp
objects. However, this accessory soon acquired cultural, aesthetic, symbolic significance, and
apparently it was not related to comfort. This work aims to analyze comfort in women
footwear, especially high heels shoe. We intended to understand the emotional relationship of
consumers with this type of accessory, as well as to understand to what extent women are
willing to give up comfort in favor of aesthetics. For this purpose, a questionnaire was
designed, aimed at the female audience in order to understand the relevance of women's
footwear, their daily relationship with shoes, the specificity of heels and the problems caused
by it.This work is supported by FEDER funds through the Competitivity Factors Operational Programme - COMPETE and by national funds through FCT – Foundation for Science and Technology within the scope of the project POCI-01-0145-FEDER-007136info:eu-repo/semantics/publishedVersio
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