Fast ReRoute on Programmable Switches

Highly dependable communication networks usually rely on some kind of Fast Re-Route (FRR) mechanism which allows to quickly re-route traffic upon failures, entirely in the data plane. This paper studies the design of FRR mechanisms for emerging reconfigurable switches. Our main contribution is an FRR primitive for programmable data planes, PURR, which provides low failover latency and high switch throughput, by avoiding packet recirculation. PURR tolerates multiple concurrent failures and comes with minimal memory requirements, ensuring compact forwarding tables, by unveiling an intriguing connection to classic ``string theory'' (i.e., stringology), and in particular, the shortest common supersequence problem. PURR is well-suited for high-speed match-action forwarding architectures (e.g., PISA) and supports the implementation of a broad variety of FRR mechanisms. Our simulations and prototype implementation (on an FPGA and a Tofino switch) show that PURR improves TCAM memory occupancy by a factor of 1.5x-10.8x compared to a naïve encoding when implementing state-of-the-art FRR mechanisms. PURR also improves the latency and throughput of datacenter traffic up to a factor of 2.8x-5.5x and 1.2x-2x, respectively, compared to approaches based on recirculating packets

An edge-queued datagram service for all datacenter traffic

Modern datacenters support a wide range of protocols and in-network switch enhancements aimed at improving performance. Unfortunately, the resulting protocols often do not coexist gracefully because they inevitably interact via queuing in the network. In this paper we describe EQDS, a new datagram service for datacenters that moves almost all of the queuing out of the core network and into the sending host. This enables it to support multiple (conflicting) higher layer protocols, while only sending packets into the network according to any receiver-driven credit scheme. EQDS can transparently speed up legacy TCP and RDMA stacks, and enables transport protocol evolution, while benefiting from future switch enhancements without needing to modify higher layer stacks. We show through simulation and multiple implementations that EQDS can reduce FCT of legacy TCP by 2x, improve the NVMeOF-RDMA throughput by 30%, and safely run TCP alongside RDMA on the same network

Development of a screening tool enabling identification of infants and toddlers at risk for family abuse and neglect : A feasibility study from three South European countries

Background: Child abuse is a health and social problem, and few screening instruments are available for the detection of risk in primary health care. The aim was to develop a screening instrument to be used by professionals in the public health care sector, thus enabling the detection of infants and toddlers at risk of emotional and physical abuse and neglect, and to provide evidence for the feasibility of the instrument in Cyprus, Greece and Spain. Method: A total of 50 health professionals from paediatric public health-care centres in the three countries were involved in a three-step process for guiding the development of the screening tool and its application. Results: A nine-item screening tool, consisting of items assessing relational emotional abuse, physical abuse and other risk factors, was developed. The screening tool was applied on a total of 219 families with 0 to 3-year-old children attending public health centres in the three countries. Clinicians reported that they agreed on the inclusion of the questions (86.4-100%) and that they found the questions to be useful for the clinical evaluation of the family (63.2-100%). Conclusion: The screening tool shows considerable face validity and was reported feasible by an international set of clinician

Editorial Redox Biology of Exercise

Redox biology is probably the most rapidly expanding field in biology. Indeed, the number of conferences, journals, and books devoted to redox biology is increasing and it is very often seen that major biology journals publish special issues on this area (e.g., Exercise is perhaps one of the most characteristic examples demonstrating that reactive species are not necessarily "harmful" entities, considering that the well-known benefits of regular exercise on muscle function and health are accompanied by repeated episodes of oxidative and nitrosative stress. In addition, an ongoing debate exists in the literature regarding the implications of antioxidant supplementation on physical performance and redox homeostasis. Considering that the redox biology of exercise is by nature multidisciplinary, this special issue is compiled of original and review articles combining chemical, analytical, biochemical, nutritional, physiological, and medical aspects relevant to reactive species biology. Reading through these papers the multiple facets of exercise redox biology are revealed. The review article by E. C. Gomes et al. presents the current state of knowledge on the redox biology of exercise. It provides a comprehensive perspective on the contribution of various intracellular and extracellular sources and the identity of oxidants produced by exercising animals and humans. It also focuses on the possible role of these exercise-induced oxidants in important training adaptations such as angiogenesis, mitochondria biogenesis, and muscle hypertrophy. This article lays the groundwork for the other articles of the special issue that address oxidant effects on exercise performance and redox homeostasis and diseases. Specifically, H. Pan et al. indicated that electrical stimulation of skeletal muscle cells increased the production of reactive species as well as the mRNA and protein levels of interleukin-6. The authors hypothesized that reactive species generation induced by skeletal muscle contraction may be one of the factors regulating musclederived interleukin-6 production and release. Using a more physiological relevant methodology, S. Mrakic-Sposta et al. employed an electron paramagnetic resonance technique for the rapid and noninvasive measurement of reactive species concentration directly in fresh human peripheral blood. Using this innovative approach, they reported that short-term high-intensity exercise increased reactive species production whereas the resting levels of reactive species decreased following supplementation with the antioxidant cofactor α-lipoic acid

Factors associated with perceived performance drops and musculoskeletal injuries in Brazilian recreational triathletes

OBJECTIVE The aim of the study was to investigate sleep characteristics, use of supplements, and training volume of recreational triathletes, and to verify possible associations with perceived performance drops and occurrence of injuries. MATERIALS AND METHODS Recreational triathletes (n=942) answered a questionnaire inquiring about their demographic characteristics, performance, injuries and training volume. RESULTS When comparing athletes who slept more (9-10 hours) with those who slept less, less sleep was associated with a higher prevalence of perceived performance drops. Regarding difficulties in initiating sleep, the absence of initiating difficulties (p<0.001) was a protective factor against perceived performance drops. Regarding weekly training volume, compared to those who trained more than 20 hours, training less than 3 hours (p<0.001), 3-5 hours (p<0.001), or 12-14 hours (p<0.001) were protective factors against perceived performance drops. Concerning training volume and injuries, we found that compared to those who trained more than 20 hours, training 18-20 hours (p<0.001), 15-17 hours (p<0.001), 12-14 hours (p<0.001), 6-8 hours (p<0.001), or 3-5 hours (p<0.001) were protective factors against injuries. CONCLUSIONS Triathletes with a lower sleep quantity and those who have difficulties initiating sleep frequently experience drops in performance. Training volumes can influence both performance and the likelihood of injuries

First results from the CERN Axion Solar Telescope (CAST)

Hypothetical axion-like particles with a two-photon interaction would be produced in the Sun by the Primakoff process. In a laboratory magnetic field (``axion helioscope'') they would be transformed into X-rays with energies of a few keV. Using a decommissioned LHC test magnet, CAST has been running for about 6 months during 2003. The first results from the analysis of these data are presented here. No signal above background was observed, implying an upper limit to the axion-photon coupling < 1.16 10^{-10} GeV^-1 at 95% CL for m_a <~0.02 eV. This limit is comparable to the limit from stellar energy-loss arguments and considerably more restrictive than any previous experiment in this axion mass range.Comment: 4 pages, accepted by PRL. Final version after the referees comment

Intensity of Resistance Exercise Determines Adipokine and Resting Energy Expenditure Responses in Overweight Elderly Individuals

OBJECTIVE - To evaluate the time course of leptin, adiponectin, and testing energy expenditure (REE) responses in overweight elderly mates after acute resistance exercise protocols of various intensity configurations. RESEARCH DESIGN AND METHODS - Forty inactive men (65-82 years) were randomly assigned to one of four groups (n = 10/group): control, low-intensity resistance exercise, moderate-intensity resistance exercise, and high-intensity resistance exercise. Exercise energy cost, REE, leptin, adiponectin, cortisol, insulin, lactate, glucose, nonesterified fatty acids (NEFAs), and glycerol were determined at baseline, immediately after exercise, and during a 72-h recovery period. RESULTS - Exercise energy cost was lower in high-intensity than in low-intensity and moderate-intensity groups (221.6 +/- 8.8 vs. 295.6 +/- 10.7 and 281.6 +/- 9.8 kcal, P < 0.001). Lactate, glucose, NEFAs, and glycerol concentrations increased (P < 0.001) after exercise and returned to baseline thereafter in all groups. REE increased (P < 0.001) in all groups at 12 h in an intensity-dependent manner (P < 0.05). REE reached baseline after 48 h in the low- and mode rate-intensity groups and after 72 h in the high-intensity group. Cortisol peaked in all active groups after exercise (P < 0.001) and remained elevated (P < 0.001) for 12 h. After adjustment for plasma volume shifts, leptin remained unaltered. Adiponectin concentration increased after 12 hand remained elevated for 24 h only in the high-intensity group (P < 0.001). CONCLUSIONS - Resistance exercise does not alter circulating leptin concentration but does increase REE and adiponectin in an intensity-dependent manner for as long as 48 and 24 h, respectively, in overweight elderly individuals. It appears that resistance exercise may represent an effective approach for weight management and metabolic control in overweight elderly individuals