445 research outputs found
Evidence for Anisotropic Vortex Dynamics and Pauli Limitation in the Upper Critical Field of FeSe1-xTex
We have determined HC2(T) for FeSe1-xTex (x=0.52) single crystals using
resistivity measurements at high static and pulsed magnetic field, as well as
specific heat measurements up to 9T. We find that the significant anisotropy of
the initial slope of HC2(T) determined from resistivity measurements, is not
present when HC2 is determined from the specific heat results. This suggests
that the thermodynamic upper critical field is almost isotropic, and that
anisotropic vortex dynamics play a role. Further evidence of anisotropic vortex
dynamics is found in the behaviour in pulsed field. We also find that Pauli
limiting must be included in order to fit the temperature dependence of HC2,
indicating probably higher effective mass in FeSe1-xTex than in other Fe
superconductors
Psuedo-isotropic upper critical field in cobalt-doped SrFe2As2 epitaxial films
The temperature and angular dependence of the upper critical field (Hc2) is
reported for cobalt-doped SrFe2As2 epitaxial films between Tc and 0.5 K in
pulsed magnetic fields up to 50 T. For H parallel c, Hc2 is close to a linear
function of temperature, while in the perpendicular direction there is
significant downward curvature that results in an Hc2 ratio (gamma =
Hc2(perpendicular)/Hc2(parallel) that decreases nearly linearly with
temperature, approaching gamma = 1 at low temperature with Hc2(0) = 47 T. We
measure the complete upper-critical field phase diagram including angular
dependence and model the data using a two band theory allowing us to determine
the anisotropy of both bands, their relative diffusivities, and the
relationship between BCS coupling constant matrix elements. We find an unusual
relationship between the diffusivities of the two bands, with two anisotropic
and opposite bands. This relationship is supported by the observation of a
local maximum for Hc2(parallel) at low temperature
Giant magnetothermopower of magnon-assisted transport in ferromagnetic tunnel junctions
We present a theoretical description of the thermopower due to
magnon-assisted tunneling in a mesoscopic tunnel junction between two
ferromagnetic metals. The thermopower is generated in the course of thermal
equilibration between two baths of magnons, mediated by electrons. For a
junction between two ferromagnets with antiparallel polarizations, the ability
of magnon-assisted tunneling to create thermopower depends on the
difference between the size of the majority and
minority band Fermi surfaces and it is proportional to a temperature dependent
factor where is the magnon Debye
energy. The latter factor reflects the fractional change in the net
magnetization of the reservoirs due to thermal magnons at temperature
(Bloch's law). In contrast, the contribution of magnon-assisted
tunneling to the thermopower of a junction with parallel polarizations is
negligible. As the relative polarizations of ferromagnetic layers can be
manipulated by an external magnetic field, a large difference results in a magnetothermopower effect. This
magnetothermopower effect becomes giant in the extreme case of a junction
between two half-metallic ferromagnets, .Comment: 9 pages, 4 eps figure
Randomizing world trade. II. A weighted network analysis
Based on the misleading expectation that weighted network properties always
offer a more complete description than purely topological ones, current
economic models of the International Trade Network (ITN) generally aim at
explaining local weighted properties, not local binary ones. Here we complement
our analysis of the binary projections of the ITN by considering its weighted
representations. We show that, unlike the binary case, all possible weighted
representations of the ITN (directed/undirected, aggregated/disaggregated)
cannot be traced back to local country-specific properties, which are therefore
of limited informativeness. Our two papers show that traditional macroeconomic
approaches systematically fail to capture the key properties of the ITN. In the
binary case, they do not focus on the degree sequence and hence cannot
characterize or replicate higher-order properties. In the weighted case, they
generally focus on the strength sequence, but the knowledge of the latter is
not enough in order to understand or reproduce indirect effects.Comment: See also the companion paper (Part I): arXiv:1103.1243
[physics.soc-ph], published as Phys. Rev. E 84, 046117 (2011
Thin Film Growth and Device Fabrication of Iron-Based Superconductors
Iron-based superconductors have received much attention as a new family of
high-temperature superconductors owing to their unique properties and distinct
differences from cuprates and conventional superconductors. This paper reviews
progress in thin film research on iron-based superconductors since their
discovery for each of five material systems with an emphasis on growth,
physical properties, device fabrication, and relevant bulk material properties.Comment: To appear in J. Phys. Soc. Jp
Pregnancy after complex myomectomy: neither age of patient nor size, number or location of fibroids should be a barrier
The effectiveness of the Liverpool care pathway in improving end of life care for dying cancer patients in hospital. A cluster randomised trial
<p>Abstract</p> <p>Background</p> <p>Most cancer patients still die in hospital, mainly in medical wards. Many studies in different countries have shown the poor quality of end-of-life care delivery in hospitals. The Program "Liverpool Care Pathway for the dying patient" (LCP), developed in the UK to transfer the hospice model of care into hospitals and other care settings, is a complex intervention to improve the quality of end-of-life care. The results from qualitative and quantitative studies suggest that the LCP Program can improve significantly the quality of end-of-life care delivery in hospitals, but no randomised trial has been conducted till now.</p> <p>Methods and design</p> <p>This is a randomized cluster trial, stratified by regions and matched for assessment period. Pairs of eligible medical wards from different hospitals will be randomized to receive the LCP-I Program or no intervention until the end of the trial. The LCP-I Program will be implemented by a Palliative Care Unit.</p> <p>The assessment of the end-points will be performed for all cancer deaths occurred in the six months after the end of the LCP-I implementation in the experimental wards and, in the same period of time, in the matched control wards. The primary end-point is the overall quality of end-of-life care provided on the ward to dying cancer patients and their families, assessed using the Global Scale of the Italian version of the Toolkit <it>"After-death Bereaved Family Member Interview</it>".</p> <p>Discussion</p> <p>This study can be interpreted as a Phase III trial according to the Medical Research Council Framework. In this study, the effectiveness of a fully defined intervention is assessed by comparing the distribution of the endpoints in the experimental and in the control arm.</p> <p>Research ID</p> <p>RFPS-2006-6-341619</p> <p>Trial registration</p> <p>ClinicalTrials.gov Identifier: <a href="http://www.clinicaltrials.gov/ct2/show/NCT01081899">NCT01081899</a></p
Anti-cancer effects and mechanism of actions of aspirin analogues in the treatment of glioma cancer
INTRODUCTION: In the past 25 years only modest advancements in glioma treatment have been made, with patient prognosis and median survival time following diagnosis only increasing from 3 to 7 months. A substantial body of clinical and preclinical evidence has suggested a role for aspirin in the treatment of cancer with multiple mechanisms of action proposed including COX 2 inhibition, down regulation of EGFR expression, and NF-κB signaling affecting Bcl-2 expression. However, with serious side effects such as stroke and gastrointestinal bleeding, aspirin analogues with improved potency and side effect profiles are being developed. METHOD: Effects on cell viability following 24 hr incubation of four aspirin derivatives (PN508, 517, 526 and 529) were compared to cisplatin, aspirin and di-aspirin in four glioma cell lines (U87 MG, SVG P12, GOS – 3, and 1321N1), using the PrestoBlue assay, establishing IC50 and examining the time course of drug effects. RESULTS: All compounds were found to decrease cell viability in a concentration and time dependant manner. Significantly, the analogue PN517 (IC50 2mM) showed approximately a twofold increase in potency when compared to aspirin (3.7mM) and cisplatin (4.3mM) in U87 cells, with similar increased potency in SVG P12 cells. Other analogues demonstrated similar potency to aspirin and cisplatin. CONCLUSION: These results support the further development and characterization of novel NSAID derivatives for the treatment of glioma
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