On the feasibility of real-time prediction of aircraft carrier motion at sea

The ability to predict the aircraft carrier's motion over an interval of several seconds within reasonable error bounds may allow an improvement in touchdown dispersion and a more certain value for ramp clearance due to a smoother aircraft trajectory. Also, improved information to the landing signal officer should decrease the number of waveoffs substantially. It is quantitatively shown that, based on the power density spectrum data for pitch and heave measured for various ships and sea conditions, the motion can be predicted well for up to 15 seconds. The zero crossover times for both pitch and heave motions can be predicted with impressive accuracy. The predictor was designed on the basis of Kalman's optimum filtering theory for the discrete time case, adapted for real-time digital computer operation

Simple processors of star tracker commands for stabilizing an inertially oriented satellite

Simple processors of star tracker commands for stabilizing inertially oriented satellit

SS433's accretion disc, wind and jets: before, during and after a major flare

The Galactic microquasar SS433 occasionally exhibits a major flare when the intensity of its emission increases significantly and rapidly. We present an analysis of high-resolution, almost-nightly optical spectra obtained before, during and after a major flare, whose complex emission lines are deconstructed into single gaussians and demonstrate the different modes of mass loss in the SS433 system. During our monitoring, an initial period of quiescence was followed by increased activity which culminated in a radio flare. In the transition period the accretion disc of SS433 became visible in H-alpha and HeI emission lines and remained so until the observations were terminated; the line-of-sight velocity of the centre of the disc lines during this time behaved as though the binary orbit has significant eccentricity rather than being circular, consistent with three recent lines of evidence. After the accretion disc appeared its rotation speed increased steadily from 500 to 700 km/s. The launch speed of the jets first decreased then suddenly increased. At the same time as the jet launch speed increased, the wind from the accretion disc doubled in speed. Two days afterwards, the radio flux exhibited a flare. These data suggest that a massive ejection of material from the companion star loaded the accretion disc and the system responded with mass loss via different modes that together comprise the flare phenomena. We find that archival data reveal similar behaviour, in that when the measured jet launch speed exceeds 0.29c this is invariably simultaneous with, or a few days before, a radio flare. Thus we surmise that a major flare consists of the overloading of the accretion disc, resulting in the speeding up of the H-alpha rotation disc lines, followed by enhanced mass loss not just via its famous jets at higher-than-usual speeds but also directly from its accretion disc's wind.Comment: Accepted by MNRA

Nanoscale Torsional Optomechanics

Optomechanical transduction is demonstrated for nanoscale torsional resonators evanescently coupled to optical microdisk whispering gallery mode resonators. The on-chip, integrated devices are measured using a fully fiber-based system, including a tapered and dimpled optical fiber probe. With a thermomechanically calibrated optomechanical noise floor down to 7 fm/sqrt(Hz), these devices open the door for a wide range of physical measurements involving extremely small torques, as little as 4x10^-20 N*m.Comment: 4 pages, 4 figures - Accepted to APL Oct 22nd, 2012. To appear in February 4th issue - as cover articl

The Dynamics and Stability of Circumbinary Orbits

We numerically investigate the dynamics of orbits in 3D circumbinary phase-space as a function of binary eccentricity and mass fraction. We find that inclined circumbinary orbits in the elliptically-restricted three-body problem display a nodal libration mechanism in the longitude of the ascending node and in the inclination to the plane of the binary. We (i) analyse and quantify the behaviour of these orbits with reference to analytical work performed by Farago & Laskar (2010) and (ii) investigate the stability of these orbits over time. This work is the first dynamically aware analysis of the stability of circumbinary orbits across both binary mass fraction and binary eccentricity. This work also has implications for exoplanetary astronomy in the existence and determination of stable orbits around binary systems.Comment: Monthly Notices of the Royal Astronomical Society. in pres

Microvascular resistance predicts myocardial salvage and infarct characteristics in ST-elevation myocardial infarction

<b>Background:</b> The pathophysiology of myocardial injury and repair in patients with ST‐elevation myocardial infarction is incompletely understood. We investigated the relationships among culprit artery microvascular resistance, myocardial salvage, and ventricular function.<p></p> <b>Methods and Results:</b> The index of microvascular resistance (IMR) was measured by means of a pressure‐ and temperature‐sensitive coronary guidewire in 108 patients with ST‐elevation myocardial infarction (83% male) at the end of primary percutaneous coronary intervention. Paired cardiac MRI (cardiac magnetic resonance) scans were performed early (2 days; n=108) and late (3 months; n=96) after myocardial infarction. T2‐weighted‐ and late gadolinium–enhanced cardiac magnetic resonance delineated the ischemic area at risk and infarct size, respectively. Myocardial salvage was calculated by subtracting infarct size from area at risk. Univariable and multivariable models were constructed to determine the impact of IMR on cardiac magnetic resonance–derived surrogate outcomes. The median (interquartile range) IMR was 28 (17–42) mm Hg/s. The median (interquartile range) area at risk was 32% (24%–41%) of left ventricular mass, and the myocardial salvage index was 21% (11%–43%). IMR was a significant multivariable predictor of early myocardial salvage, with a multiplicative effect of 0.87 (95% confidence interval 0.82 to 0.92) per 20% increase in IMR; P<0.001. In patients with anterior myocardial infarction, IMR was a multivariable predictor of early and late myocardial salvage, with multiplicative effects of 0.82 (95% confidence interval 0.75 to 0.90; P<0.001) and 0.92 (95% confidence interval 0.88 to 0.96; P<0.001), respectively. IMR also predicted the presence and extent of microvascular obstruction and myocardial hemorrhage.<p></p> <b>Conclusion:</b> Microvascular resistance measured during primary percutaneous coronary intervention significantly predicts myocardial salvage, infarct characteristics, and left ventricular ejection fraction in patients with ST‐elevation myocardial infarction.<p></p&gt

The precession of SS433's radio ruff on long timescales

Roughly perpendicular to SS433's famous precessing jets is an outflowing "ruff" of radio-emitting plasma, revealed by direct imaging on milli-arcsecond scales. Over the last decade, images of the ruff reveal that its orientation changes over time with respect to a fixed sky co-ordinate grid. For example, during two months of daily observations with the VLBA by Mioduszewski et al. (2004), a steady rotation through ~10 degrees is observed whilst the jet angle changes by ~20 degrees. The ruff reorientation is not coupled with the well-known precession of SS433's radio jets, as the ruff orientation varies across a range of 69 degrees whilst the jet angle varies across 40 degrees, and on greatly differing and non-commensurate timescales. It has been proposed that the ruff is fed by SS433's circumbinary disk, discovered by a sequence of optical spectroscopy by Blundell et al. (2008), and so we present the results of 3D numerical simulations of circumbinary orbits. These simulations show precession in the longitude of the ascending node of all inclined circumbinary orbits - an effect which would be manifested as the observed ruff reorientation. Matching the rate of ruff precession is possible if circumbinary components are sufficiently close to the binary system, but only if the binary mass fraction is close to equality and the binary eccentricity is non-zero.Comment: 4 pages, 5 figures, to be published in ApJ Le

Cholinergic modulation of disorder-relevant human defensive behaviour in generalised anxiety disorder

Drugs that are clinically effective against anxiety disorders modulate the innate defensive behaviour of rodents, suggesting these illnesses reflect altered functioning in brain systems that process threat. This hypothesis is supported in humans by the discovery that the intensity of threat-avoidance behaviour is altered by the benzodiazepine anxiolytic lorazepam. However, these studies used healthy human participants, raising questions as to their validity in anxiety disorder patients, as well as their generalisability beyond GABAergic benzodiazepine drugs. BNC210 is a novel negative allosteric modulator of the alpha 7 nicotinic acetylcholine receptor and we recently used functional Magnetic Resonance Imaging to show it reduced amygdala responses to fearful faces in generalised anxiety disorder patients. Here we report the effect of BNC210 on the intensity of threat-avoidance behaviour in 21 female GAD patients from the same cohort. We used the Joystick Operated Runway Task as our behavioural measure, which is a computerised human translation of the Mouse Defense Test Battery, and the Spielberger state anxiety inventory as our measure of state affect. Using a repeated-measures, within-subjects design we assessed the effect of BNC210 at two dose levels versus placebo (300 mg and 2000 mg) upon two types of threat-avoidance behaviour (Flight Intensity and Risk Assessment Intensity). We also tested the effects of 1.5 mg of the benzodiazepine lorazepam as an active control. BNC210 significantly reduced Flight Intensity relative to placebo and the low dose of BNC210 also significantly reduced self-reported state anxiety. Risk Assessment Intensity was not significantly affected. Results show both human defensive behaviour and state anxiety are influenced by cholinergic neurotransmission and there provide converging evidence that this system has potential as a novel target for anxiolytic pharmacotherapy