3,551 research outputs found
Visual adaptation to convexity in macaque area V4
Aftereffects are perceptual illusions caused by visual adaptation to one or more stimulus attribute, such as orientation, motion, or shape. Neurophysiological studies seeking to understand the basis of visual adaptation have observed firing rate reduction and changes in tuning of stimulus-selective neurons following periods of prolonged visual stimulation. In the domain of shape, recent psychophysical work has shown that adaptation to a convex pattern induces a subsequently seen rectangle to appear slightly concave. In the present study, we investigate the possible contribution of V4 neurons of rhesus monkeys, which are thought to be involved in the coding of convexity, to shape-specific adaptation. Visually responsive neurons were monitored during the brief presentation of simple shapes varying in their convexity level. Each test presentation was preceded by either a blank period or several seconds of adaptation to a convex or concave stimulus, presented in two different sizes. Adaptation consistently shifted the tuning of neurons away from the convex or concave adapter, including shifting response to the neutral rectangle in the direction of the opposite convexity. This repulsive shift resembled the known perceptual distortion associated with adaptation to such stimuli. In addition, adaptation caused a nonspecific response decrease, as well as a specific decrease for repeated stimuli. The latter effects were observed whether or not the adapting and test stimuli matched closely in their size. Taken together, these results provide evidence for shape-specific adaptation of neurons in area V4, which may contribute to the perception of the convexity aftereffect
On quasilinear parabolic evolution equations in weighted Lp-spaces II
Our study of abstract quasi-linear parabolic problems in time-weighted
L_p-spaces, begun in [17], is extended in this paper to include singular lower
order terms, while keeping low initial regularity. The results are applied to
reaction-diffusion problems, including Maxwell-Stefan diffusion, and to
geometric evolution equations like the surface-diffusion flow or the Willmore
flow. The method presented here will be applicable to other parabolic systems,
including free boundary problems.Comment: 21 page
The Error and Repair Catastrophes: A Two-Dimensional Phase Diagram in the Quasispecies Model
This paper develops a two gene, single fitness peak model for determining the
equilibrium distribution of genotypes in a unicellular population which is
capable of genetic damage repair. The first gene, denoted by ,
yields a viable organism with first order growth rate constant if it
is equal to some target ``master'' sequence . The second
gene, denoted by , yields an organism capable of genetic repair
if it is equal to some target ``master'' sequence . This
model is analytically solvable in the limit of infinite sequence length, and
gives an equilibrium distribution which depends on \mu \equiv L\eps , the
product of sequence length and per base pair replication error probability, and
\eps_r , the probability of repair failure per base pair. The equilibrium
distribution is shown to exist in one of three possible ``phases.'' In the
first phase, the population is localized about the viability and repairing
master sequences. As \eps_r exceeds the fraction of deleterious mutations,
the population undergoes a ``repair'' catastrophe, in which the equilibrium
distribution is still localized about the viability master sequence, but is
spread ergodically over the sequence subspace defined by the repair gene. Below
the repair catastrophe, the distribution undergoes the error catastrophe when exceeds \ln k/\eps_r , while above the repair catastrophe, the
distribution undergoes the error catastrophe when exceeds , where denotes the fraction of deleterious mutations.Comment: 14 pages, 3 figures. Submitted to Physical Review
Comment on "Antilocalization in a 2D Electron Gas in a Random Magnetic Field"
In a recent Letter, Taras-Semchuk and Efetov reconsider the problem of
electron localization in a random magnetic field in two dimensions. They claim
that due to the long-range nature of the vector potential correlations an
additional term appears in the effective field theory (-model) of the
problem, leading to delocalization at the one-loop level. This calls into
question the results of earlier analytical studies, where the random magnetic
field problem was mapped onto the conventional unitary-class -model,
implying that the leading quantum correction is of two-loop order and of a
localizing nature. We show in this Comment, however, that the new term in fact
does not exist and was erroneously obtained by Taras-Semchuk and Efetov because
of an inconsistent treatment violating gauge invariance.Comment: 1 page, 2 figure
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Optical and x-ray imaging of electron beams using synchrotron emission
In the case of very low eniittance electron and positron storage ring beams, it is impossible to make intrusive measurements of beam properties without increasing the emittance and possibly disrupting the beam. In cases where electron or positron beams have high average power densities (such as free electron laser linacs), intrusive probes such as wires and optical transition radiation screens or Cherenkov emitting screens can be easily damaged or destroyed. The optical and x-ray emissions from the bends in the storage rings and often from linac bending magnets can be used to image the beam profile to obtain emittance information about the beam. The techniques, advantages and limitations of using both optical and x-ray synchrotron emission to measure beam properties are discussed and the possibility of single bunch imaging is considered. The properties of suitable imagers and converters such as phosphors are described. Examples of previous, existing and planned applications are given where available, including a pinhole imaging system currently being designed for the Advanced Photon Source at Argonne National Laboratory
Adaptive Dispersion Compensation for Remote Fiber Delivery of NIR Femtosecond Pulses
We report on remote delivery of 25 pJ broadband near-infrared femtosecond
light pulses from a Ti:sapphire laser through 150 meters of single-mode optical
fiber. Pulse distortion due to dispersion is overcome with pre-compensation
using adaptive pulse shaping techniques, while nonlinearities are mitigated
using an SF10 rod for the final stage of pulse compression. Near transform
limited pulse duration of 130 fs is measured after the final compression.Comment: 3 pages, 4 figure
Nanoscale grains, high irreversibility field, and large critical current density as a function of high energy ball milling time in C-doped magnesium diboride
Magnesium diboride (MgB2) powder was mechanically alloyed by high energy ball
milling with C to a composition of Mg(B0.95C0.05)2 and then sintered at 1000 C
in a hot isostatic press. Milling times varied from 1 minute to 3000 minutes.
Full C incorporation required only 30-60 min of milling. Grain size of sintered
samples decreased with increased milling time to less than 30 nm for 20-50 hrs
of milling. Milling had a weak detrimental effect on connectivity. Strong
irreversibility field (H*) increase (from 13.3 T to 17.2 T at 4.2 K) due to
increased milling time was observed and correlated linearly with inverse grain
size (1/d). As a result, high field Jc benefited greatly from lengthy powder
milling. Jc(8 T, 4.2 K) peaked at > 80,000 A/cm2 with 1200 min of milling
compared with only ~ 26,000 A/cm2 for 60 min of milling. This non-compositional
performance increase is attributed to grain refinement of the unsintered powder
by milling, and to the probable suppression of grain growth by milling-induced
MgO nano-dispersions.Comment: 12 pages, 11 figure
Potential, core-level and d band shifts at transition metal surfaces
We have extended the validity of the correlation between the surface
3d-core-level shift (SCLS) and the surface d band shift (SDBS) to the entire 4d
transition metal series and to the neighboring elements Sr and Ag via accurate
first-principles calculations. We find that the correlation is quasilinear and
robust with respect to the differencies both between initial and final-state
calculations of the SCLS's and two distinct measures of the SDBS's. We show
that despite the complex spatial dependence of the surface potential shift
(SPS) and the location of the 3d and 4d orbitals in different regions of space,
the correlation exists because the sampling of the SPS by the 3d and 4d
orbitals remains similar. We show further that the sign change of the SCLS's
across the transition series does indeed arise from the d band-narrowing
mechanism previously proposed. However, while in the heavier transition metals
the predicted increase of d electrons in the surface layer relative to the bulk
arises primarily from transfers from s and p states to d states within the
surface layer, in the lighter transition metals the predicted decrease of
surface d electrons arises primarily from flow out into the vacuum.Comment: RevTex, 22 pages, 5 figures in uufiles form, to appear in Phys.Rev.
Crossover to Non-universal Microscopic Spectral Fluctuations in Lattice Gauge Theory
The spectrum of the Dirac operator near zero virtuality obtained in lattice
gauge simulations is known to be universally described by chiral random matrix
theory. We address the question of the maximum energy for which this
universality persists. For this purpose, we analyze large ensembles of complete
spectra of the Euclidean Dirac operator for staggered fermions. We calculate
the disconnected scalar susceptibility and the microscopic number variance for
the chiral symplectic ensemble of random matrices and compare the results with
lattice Dirac spectra for quenched SU(2). The crossover to a non-universal
regime is clearly identified and found to scale with the square of the linear
lattice size and with , in agreement with theoretical expectations.Comment: 11 pages, 7 figures, misprint in Eq. (13) corrected, minor
modifications, to appear in Phys. Lett.
Robustness and epistasis in mutation-selection models
We investigate the fitness advantage associated with the robustness of a
phenotype against deleterious mutations using deterministic mutation-selection
models of quasispecies type equipped with a mesa shaped fitness landscape. We
obtain analytic results for the robustness effect which become exact in the
limit of infinite sequence length. Thereby, we are able to clarify a seeming
contradiction between recent rigorous work and an earlier heuristic treatment
based on a mapping to a Schr\"odinger equation. We exploit the quantum
mechanical analogy to calculate a correction term for finite sequence lengths
and verify our analytic results by numerical studies. In addition, we
investigate the occurrence of an error threshold for a general class of
epistatic landscape and show that diminishing epistasis is a necessary but not
sufficient condition for error threshold behavior.Comment: 20 pages, 14 figure
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