A New Classification Of UK Local Authorities Using 2001 Census Key Statistics

The 2001 Census has been successfully administered and the Census Organisations are currently engaged in processing the returns. A very large and rich dataset will be produced for the 58,789,194 people of the UK. The Census Area Statistics, for example, delivers 190 tables containing about 6 thousand unique counts relating to the characteristics of the UK population, for output areas and all higher geographies. This paper represents the first results of a project that aims to develop, in collaboration with the Office for National Statistics, a set of general purpose classifications at different geographic scales, including households, neighbourhoods, wards, local authorities and to link the classifications at different levels together. The paper reports on the methods used and results of a classification of the UK’s 434 Local Authorities, using the Key Statistics released in February 2003. This initial classification and description of methods will feed into the ONS/GROS/NISRA project to classify Local Authorities for the whole UK. Further data or digital versions of the classification system are available on request

Creating the National Classification of Census Output Areas: Data, Methods and Results

The purpose of this paper is to describe and explain the processes and decisions that were involved in the creation of the National Area Classification of 2001 Census Output Areas (OAs). The project was carried out on behalf of the Office for National Statistics (ONS) by Daniel Vickers of the School of Geography, University of Leeds as part of his PhD. thesis. The paper describes the creation of the classification: selection of the variables, assembly of the classification database, the methods of standardisation and the clustering procedures, some discussion of alternative methodologies that were considered for use. The processes used for creating the clusters, their naming and description are outlined. The classification is mapped and visualised in a number of different ways. The OA Classification fits into the ONS suite of area classifications complementing published classifications at Local Authority, Health Authority and Ward levels. The classification is freely available, and can be downloaded from the ONS Neighbourhood Statistics website at www.statistics.gov.uk

Distributed microprocessors in a tactical universal modem

The distributed microprocessor system associated with a wideband signal conversion unit (WBSCU) is described. Multiple embedded 8086 and 2901 microprocessors, supported by dedicated hardware modules, perform the required real time operations for both transmit and receive functions. Commands from a host computer determine the configuration of the WBSCU via the IEEE 488 bus. Each of the four WBSCU channels is assigned to process a specified IF waveform; each channel configures its own resources and, in some cases, borrows resources from other channels. The processed waveform data is communicated from individual channels to redundant global memories. Data flow between the user community and global memories occurs via redundant 1553 buses through intelligent Bus Interface Units. Each WBSCU channel contains one 2901 bit slice machine and one 8086 microprocessor. The 2901 provides high speed processing capability for the most time critical operations. The 8086 is used for lower speed processing tasks where its high level language capability can be better exploited. Each 8086 has a global bus for wideband interprocessor communication, and a local bus for 8086/2901, master/slave communication. Software architecture consists of a control and communications structure governing mode dependent signal processing tasks

Systematic reviews of complementary therapies – an annotated bibliography. Part 2: Herbal medicine

Background Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical trials in three major complementary therapies (acupuncture, herbal medicine, homeopathy). This article is dealing with herbal medicine. Potentially relevant reviews were searched through the register of the Cochrane Complementary Medicine Field, the Cochrane Library, Medline, and bibliographies of articles and books. To be included articles had to review prospective clinical trials of herbal medicines; had to describe review methods explicitly; had to be published; and had to focus on treatment effects. Information on conditions, interventions, methods, results and conclusions was extracted using a pre-tested form and summarized descriptively. Results From a total of 79 potentially relevant reviews pre-selected in the screening process 58 met the inclusion criteria. Thirty of the reports reviewed ginkgo (for dementia, intermittent claudication, tinnitus, and macular degeneration), hypericum (for depression) or garlic preparations (for cardiovascular risk factors and lower limb atherosclerosis). The quality of primary studies was criticized in the majority of the reviews. Most reviews judged the available evidence as promising but definitive conclusions were rarely possible. Conclusions Systematic reviews are available on a broad range of herbal preparations prescribed for defined conditions. There is very little evidence on the effectiveness of herbalism as practised by specialist herbalists who combine herbs and use unconventional diagnosis

A unified framework of immunological and epidemiological dynamics for the spread of viral infections in a simple network-based population

<p>Abstract</p> <p>Background</p> <p>The desire to better understand the immuno-biology of infectious diseases as a broader ecological system has motivated the explicit representation of epidemiological processes as a function of immune system dynamics. While several recent and innovative contributions have explored unified models across cellular and organismal domains, and appear well-suited to describing particular aspects of intracellular pathogen infections, these existing immuno-epidemiological models lack representation of certain cellular components and immunological processes needed to adequately characterize the dynamics of some important epidemiological contexts. Here, we complement existing models by presenting an alternate framework of anti-viral immune responses within individual hosts and infection spread across a simple network-based population.</p> <p>Results</p> <p>Our compartmental formulation parsimoniously demonstrates a correlation between immune responsiveness, network connectivity, and the natural history of infection in a population. It suggests that an increased disparity between people's ability to respond to an infection, while maintaining an average immune responsiveness rate, may worsen the overall impact of an outbreak within a population. Additionally, varying an individual's network connectivity affects the rate with which the population-wide viral load accumulates, but has little impact on the asymptotic limit in which it approaches. Whilst the clearance of a pathogen in a population will lower viral loads in the short-term, the longer the time until re-infection, the more severe an outbreak is likely to be. Given the eventual likelihood of reinfection, the resulting long-run viral burden after elimination of an infection is negligible compared to the situation in which infection is persistent.</p> <p>Conclusion</p> <p>Future infectious disease research would benefit by striving to not only continue to understand the properties of an invading microbe, or the body's response to infections, but how these properties, jointly, affect the propagation of an infection throughout a population. These initial results offer a refinement to current immuno-epidemiological modelling methodology, and reinforce how coupling principles of immunology with epidemiology can provide insight into a multi-scaled description of an ecological system. Overall, we anticipate these results to as a further step towards articulating an integrated, more refined epidemiological theory of the reciprocal influences between host-pathogen interactions, epidemiological mixing, and disease spread.</p

Current crisis or artifact of surveillance: insights into rebound chlamydia rates from dynamic modelling

<p>Abstract</p> <p>Background</p> <p>After initially falling in the face of intensified control efforts, reported rates of sexually transmitted chlamydia in many developed countries are rising. Recent hypotheses for this phenomenon have broadly focused on improved case finding or an increase in the prevalence. Because of many complex interactions behind the spread of infectious diseases, dynamic models of infection transmission are an effective means to guide learning, and assess quantitative conjectures of epidemiological processes. The objective of this paper is to bring a unique and robust perspective to observed chlamydial patterns through analyzing surveillance data with mathematical models of infection transmission.</p> <p>Methods</p> <p>This study integrated 25-year testing volume data from the Canadian province of Saskatchewan with one susceptible-infected-treated-susceptible and three susceptible-infected-treated-removed compartmental models. Calibration of model parameters to fit observed 25-year case notification data, after being combined with testing records, placed constraints on model behaviour and allowed for an approximation of chlamydia prevalence to be estimated. Model predictions were compared to observed case notification trends, and extensive sensitivity analyses were performed to confirm the robustness of model results.</p> <p>Results</p> <p>Model predictions accurately mirrored historic chlamydial trends including an observed rebound in the mid 1990s. For all models examined, the results repeatedly highlighted that increased testing volumes, rather than changes in the sensitivity and specificity of testing technologies, sexual behaviour, or truncated immunological responses brought about by treatment can, explain the increase in observed chlamydia case notifications.</p> <p>Conclusions</p> <p>Our results highlight the significant impact testing volume can have on observed incidence rates, and that simple explanations for these observed increases appear to have been dismissed in favor of changes to the underlying prevalence. These simple methods not only demonstrate geographic portability, but the results reassure the public health effort towards monitoring and controlling chlamydia.</p

The effect of healthy aging on change detection and sensitivity to predictable structure in crowded acoustic scenes

The auditory system plays a critical role in supporting our ability to detect abrupt changes in our surroundings. Here we study how this capacity is affected in the course of healthy ageing. Artifical acoustic ‘scenes’, populated by multiple concurrent streams of pure tones (‘sources’) were used to capture the challenges of listening in complex acoustic environments. Two scene conditions were included: REG scenes consisted of sources characterized by a regular temporal structure. Matched RAND scenes contained sources which were temporally random. Changes, manifested as the abrupt disappearance of one of the sources, were introduced to a subset of the trials and participants (‘young’ group N = 41, age 20-38 years; ‘older’ group N = 41, age 60-82 years) were instructed to monitor the scenes for these events. Previous work demonstrated that young listeners exhibit better change detection performance in REG scenes, reflecting sensitivity to temporal structure. Here we sought to determine: (1) Whether ‘baseline’ change detection ability (i.e. in RAND scenes) is affected by age. (2) Whether aging affects listeners’ sensitivity to temporal regularity. (3) How change detection capacity relates to listeners’ hearing and cognitive profile (a battery of tests that capture hearing and cognitive abilities hypothesized to be affected by aging). The results demonstrated that healthy aging is associated with reduced sensitivity to abrupt scene changes in RAND scenes but that performance does not correlate with age or standard audiological measures such as pure tone audiometry or speech in noise performance. Remarkably older listeners’ change detection performance improved substantially (up to the level exhibited by young listeners) in REG relative to RAND scenes. This suggests that the ability to extract and track the regularity associated with scene sources, even in crowded acoustic environments, is relatively preserved in older listeners

THE INFLUENCE OF PARTICLE CONCENTRATION ON THE FLUID PHASE OF AN AXISYMMETRIC MULTIPHASE IMPINGING JET

Particle image velocimetry (PIV) is used to determine the effect of particle concentration on the fluid phase of a solid-liquid multiphase impinging jet. Two spherical particles were considered, polystyrene of 1050 kg m-3 and glass of 2450 kg m-3, both with a diameter of 225 μm. The fluid axial and radial velocities are measured with particle volume fractions (φ) equal to 0, 1x10-4, 2x10-4 and 4x10-4.For both particle types as the concentration is increased, the level of axial velocity retained immediately prior to impingement (at 6 diameters from the pipe exit) also increases. At low particle concentrations the particles have little effect on the flow turbulence, however, at higher particle concentrations the particle effect becomes more significant, with a near doubling of the peak axial RMS velocity one diameter from the jet outlet in one case. The introduction of polystyrene particles has the effect of dampening radial and axial RMS velocities, except for at the highest concentration immediately after the jet outlet where the axial turbulence is enhanced by the particles

Glory He Ascendent : An Easter Carol

https://digitalcommons.library.umaine.edu/mmb-vp/4521/thumbnail.jp