18,159 research outputs found
Scalability Analysis of Parallel GMRES Implementations
Applications involving large sparse nonsymmetric linear systems encourage parallel implementations of robust iterative solution methods, such as GMRES(k). Two parallel versions of GMRES(k) based on different data distributions and using Householder reflections in the orthogonalization phase, and variations of these which adapt the restart value k, are analyzed with respect to scalability (their ability to maintain fixed efficiency with an increase in problem size and number of processors).A theoretical algorithm-machine model for scalability is derived and validated by experiments on three parallel computers, each with different machine characteristics
The associations of adipokines with selected markers of the renin-angiotensinogen-aldosterone system: the multi-ethnic study of atherosclerosis.
Among obese individuals, increased sympathetic nervous system (SNS) activity results in increased renin and aldosterone production, as well as renal tubular sodium reabsorption. This study determined the associations between adipokines and selected measures of the renin-angiotensinogen-aldosterone system (RAAS). The sample consisted of 1970 men and women from the Multi-Ethnic Study of Atherosclerosis who were free of clinical cardiovascular disease at baseline and had blood assayed for adiponectin, leptin, plasma renin activity (PRA) and aldosterone. The mean age was 64.7 years and 50% were female. The mean (s.d.) PRA and aldosterone were 1.45 (0.56) ng ml(-1) and 150.1 (130.5) pg ml(-1), respectively. After multivariable adjustment, a 1-s.d. increment of leptin was associated with a 0.55 ng ml(-1) higher PRA and 8.4 pg ml(-1) higher aldosterone (P<0.01 for both). Although adiponectin was not significantly associated with PRA levels, the same increment in this adipokine was associated with lower aldosterone levels (-5.5 pg ml(-1), P=0.01). Notably, the associations between aldosterone and both leptin and adiponectin were not materially changed with additional adjustment for PRA. Exclusion of those taking antihypertensive medications modestly attenuated the associations. The associations between leptin and both PRA and aldosterone were not different by gender but were significantly stronger among non-Hispanic Whites and Chinese Americans than African and Hispanic Americans (P<0.01). The findings suggest that both adiponectin and leptin may be relevant to blood pressure regulation via the RAAS, in that the associations appear to be robust to antihypertension medication use and that the associations are likely different by ethnicity
Mutual information for examining correlations in DNA
This paper examines two methods for finding whether long-range correlations
exist in DNA: a fractal measure and a mutual information technique. We evaluate
the performance and implications of these methods in detail. In particular we
explore their use comparing DNA sequences from a variety of sources. Using
software for performing in silico mutations, we also consider evolutionary
events leading to long range correlations and analyse these correlations using
the techniques presented. Comparisons are made between these virtual sequences,
randomly generated sequences, and real sequences. We also explore correlations
in chromosomes from different species.Comment: 8 pages, 3 figure
The differences in local translatome across distinct neuron types is mediated by both baseline cellular differences and post-transcriptional mechanisms
Striped Magnetic Ground State of the Kagome Lattice in Fe4Si2Sn7O16
We have experimentally identified a new magnetic ground state for the kagome
lattice, in the perfectly hexagonal Fe2+ (3d6, S = 2) compound Fe4Si2Sn7O16.
Representational symmetry analysis of neutron diffraction data shows that below
T_N = 3.5 K, the spins on 2/3 of the magnetic ions order into canted
antiferromagnetic chains, separated by the remaining 1/3 which are
geometrically frustrated and show no long-range order down to at least T = 0.1
K. Moessbauer spectroscopy confirms that there is no static order on the latter
1/3 of the magnetic ions - i.e., they are in a liquid-like rather than a frozen
state - down to at least 1.65 K. A heavily Mn-doped sample
Fe1.45Mn2.55Si2Sn7O16 has the same magnetic structure. Although the propagation
vector q = (0, 1/2 , 1/2 ) breaks hexagonal symmetry, we see no evidence for
magnetostriction in the form of a lattice distortion within the resolution of
our data. We discuss the relationship to partially frustrated magnetic order on
the pyrochlore lattice of Gd2Ti2O7, and to theoretical models that predict
symmetry breaking ground states for perfect kagome lattices.Comment: 5 pages, 5 figure
As-built design specification for LACIE phase 3 automatic status and tracking system
There are no author-identified significant results in this report
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