Supersymmetric Quantum Mechanics for String-Bits

We develop possible versions of supersymmetric single particle quantum mechanics, with application to superstring-bit models in view. We focus principally on space dimensions $d=1,2,4,8$, the transverse dimensionalities of superstring in $3,4,6,10$ space-time dimensions. These are the cases for which ``classical'' superstring makes sense, and also the values of $d$ for which Hooke's force law is compatible with the simplest superparticle dynamics. The basic question we address is: When is it possible to replace such harmonic force laws with more general ones, including forces which vanish at large distances? This is an important question because forces between string-bits that do not fall off with distance will almost certainly destroy cluster decomposition. We show that the answer is affirmative for $d=1,2$, negative for $d=8$, and so far inconclusive for $d=4$.Comment: 17 pages, Late

Generalized Paraxial Ray Trace Procedure Derived from Geodesic Deviation

Paraxial ray tracing procedures have become widely accepted techniques for acoustic models in seismology and underwater acoustics. To date a generic form of these procedures including fluid motion and time dependence has not appeared in the literature. A detailed investigation of the characteristic curves of the equations of hydrodynamics allows for an immediate generalization of the procedure to be extracted from the equation form geodesic deviation. The general paraxial ray trace equations serve as an ideal supplement to ordinary ray tracing in predicting the deformation of acoustic beams in random environments. The general procedure is derived in terms of affine parameterization and in a coordinate time parameterization ideal for application to physical acoustic ray propagation. The formalism is applied to layered media, where the deviation equation reduces to a second order differential equation for a single field with a general solution in terms of a depth integral along the ray path. Some features are illustrated through special cases which lead to exact solutions in terms of either ordinary or special functions.Comment: Original; 40 pages (double spaced), 1 figure Replaced version; 36 pages single spaced, 7 figures. Expanded content; Complete derivation of the equations from the equations of hydrodynamics, introduction of an auxiliary basis for three dimensional wave-front modeling. Typos in text and equations correcte

Easy on that trigger dad: a study of long term family photo retrieval

We examine the effects of new technologies for digital photography on people's longer term storage and access to collections of personal photos. We report an empirical study of parents' ability to retrieve photos related to salient family events from more than a year ago. Performance was relatively poor with people failing to find almost 40% of pictures. We analyze participants' organizational and access strategies to identify reasons for this poor performance. Possible reasons for retrieval failure include: storing too many pictures, rudimentary organization, use of multiple storage systems, failure to maintain collections and participants' false beliefs about their ability to access photos. We conclude by exploring the technical and theoretical implications of these findings

Instanton operators in five-dimensional gauge theories

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are creditedN.L. is supported in part by STFC grant ST/J002798/1. C.P. is a Royal Society Research Fellow.N.L. is supported in part by STFC grant ST/J002798/1. C.P. is a Royal Society Research Fellow.N.L. is supported in part by STFC grant ST/J002798/1. OPen Aceess funded by SCOAP

All-fibre source of amplitude-squeezed light pulses

An all-fibre source of amplitude squeezed solitons utilizing the self-phase modulation in an asymmetric Sagnac interferometer is experimentally demonstrated. The asymmetry of the interferometer is passively controlled by an integrated fibre coupler, allowing for the optimisation of the noise reduction. We have carefully studied the dependence of the amplitude noise on the asymmetry and the power launched into the Sagnac interferometer. Qualitatively, we find good agreement between the experimental results, a semi-classical theory and earlier numerical calculations [Schmitt etl.al., PRL Vol. 81, p.2446, (1998)]. The stability and flexibility of this all-fibre source makes it particularly well suited to applications in quantum information science

Role of the unique N-terminal domain of CtBP2 in determining the subcellular localisation of CtBP family proteins

BACKGROUND: CtBP1 and CtBP2 are transcriptional co-repressors that modulate the activity of a large number of transcriptional repressors via the recruitment of chromatin modifiers. Many CtBP-regulated proteins are involved in pathways associated with tumorigenesis, including TGF-beta and Wnt signalling pathways and cell cycle regulators such as RB/p130 and HDM2, as well as adenovirus E1A. CtBP1 and CtBP2 are highly similar proteins, although evidence is emerging that their activity can be differentially regulated, particularly through the control of their subcellular localisation. CtBP2s from diverse species contain a unique N-terminus, absent in CtBP1 that plays a key role in controlling the nuclear-cytoplasmic distribution of the protein.RESULTS: Here we show that amino acids (a.a.) 4-14 of CtBP2 direct CtBP2 into an almost exclusively nuclear distribution in cell lines of diverse origins. Whilst this sequence contains similarity to known nuclear localisation motifs, it cannot drive nuclear localisation of a heterologous protein, but rather has been shown to function as a p300 acetyltransferase-dependent nuclear retention sequence. Here we define the region of CtBP2 required to co-operate with a.a. 4-14 to promote CtBP2 nuclear accumulation as being within a.a. 1-119. In addition, we show that a.a. 120-445 of CtBP2 can also promote CtBP2 nuclear accumulation, independently of a.a. 4-14. Finally, CtBP1 and CtBP2 can form heterodimers, and we show that the interaction with CtBP2 is one mechanism whereby CtBP1 can be recruited to the nucleus.CONCLUSION: Together, these findings represent key distinctions in the regulation of the functions of CtBP family members that may have important implications as to their roles in development, and cell differentiation and survival.<br/

Klassifikationsmodelle in der Gesundheitsförderung und Prävention: Möglichkeiten und Grenzen für die Konzeption und Evaluation von Projekten und Programmen

Zusammenfassung: Hintergrund: Um die komplexe Planung und Evaluation von Projekten und Programmen im Gesundheitsbereich zu unterstützen, kommen heute v.a. im angelsächsischen Raum unterschiedliche Klassifikationsmodelle zum Einsatz. In diesem Artikel geht es um eine kritische Prüfung von 2 Klassifikationsmodellen, die derzeit in diversen Institutionen der Schweiz angewendet werden. Methode: Das Ergebnismodell von Gesundheitsförderung Schweiz sowie das "Program-Logic-Modell" von Sue Funnell werden als 2 Typen von Klassifikationsmodellen verglichen und auf ihre Einsatzmöglichkeiten in der Planungs- und Evaluationsphase von Gesundheitsprojekten untersucht. Dazu verdeutlichen wir die vielfältigen Implikationen von Klassifikationssystemen im Gesundheitsbereich und zeigen anhand von 2 Fallstudien die Problematiken bei der praktischen Umsetzung der Modelle. Ergebnisse: Die Modelle basieren auf unterschiedlichen, impliziten Annahmen und unterscheiden sich im Strukturierungsgrad der Kategorien sowie im Grad der Explizierung von Kausalitäten. Bei der Nutzung der Modelle ergeben sich dadurch spezifische Vor- und Nachteile. Schlussfolgerungen: Unter Berücksichtigung ihrer Grenzen und inhärenten Logik sind Klassifikationsmodelle nützliche Instrumente, um die Komplexität in der Planung und Evaluation von Gesundheitsprojekten zu reduzieren. Darüber hinaus erzwingen sie einen Austausch der Stakeholder über Gesundheitsvorstellungen und Ziele im Gesundheitsbereic

Structure of the Effective Potential in Nonrelativistic Chern-Simons Field Theory

We present the scalar field effective potential for nonrelativistic self-interacting scalar and fermion fields coupled to an Abelian Chern-Simons gauge field. Fermions are non-minimally coupled to the gauge field via a Pauli interaction. Gauss's law linearly relates the magnetic field to the matter field densities; hence, we also include radiative effects from the background gauge field. However, the scalar field effective potential is transparent to the presence of the background gauge field to leading order in the perturbative expansion. We compute the scalar field effective potential in two gauge families. We perform the calculation in a gauge reminiscent of the $R_\xi$-gauge in the limit $\xi\rightarrow 0$ and in the Coulomb family gauges. The scalar field effective potential is the same in both gauge-fixings and is independent of the gauge-fixing parameter in the Coulomb family gauge. The conformal symmetry is spontaneously broken except for two values of the coupling constant, one of which is the self-dual value. To leading order in the perturbative expansion, the structure of the classical potential is deeply distorted by radiative corrections and shows a stable minimum around the origin, which could be of interest when searching for vortex solutions. We regularize the theory with operator regularization and a cutoff to demonstrate that the results are independent of the regularization scheme.Comment: 24 pages, UdeM-LPN-TH-93-185, CRM-192

Nonrelativistic Limit of the Scalar Chern-Simons Theory and the Aharonov-Bohm Scattering

We study the nonrelativistic limit of the quantum theory of a Chern-Simons field minimally coupled to a scalar field with quartic self-interaction. The renormalization of the relativistic model, in the Coulomb gauge, is discussed. We employ a procedure to calculate scattering amplitudes for low momenta that generates their $|p|/m$ expansion and separates the contributions coming from high and low energy intermediary states. The two body scattering amplitude is calculated up to order $p^2/m^2$. It is shown that the existence of a critical value of the self-interaction parameter for which the 2-particle scattering amplitude reduces to the Aharonov-Bohm one is a strictly nonrelativistic feature. The subdominant terms correspond to relativistic corrections to the Aharonov-Bohm scattering. A nonrelativistic reduction scheme and an effective nonrelativistic Lagrangian to account for the relativistic corrections are proposed.Comment: 22 pages, 8 figures, revtex, to be published in Int. J. Mod. Phys.