Emergency Air Protection: A Survey of Smog Alarm Systems

As Central and Eastern Europe looks to its future, it is faced with a legacy of environmental pollution from its recent past. Three main environmental tasks confront the region: to reduce the burden of pollutants, to revitalize the environment, and to prevent future pollution by implementing "clean technologies." Unfortunately, the funds are not available for taking on all of these huge tasks at once, at least not in an effective way. For this reason it is of utmost importance to set near-term priorities for environmental protection. Faced with a difficult decision, perhaps we must choose the protection of human health as a number one near-term priority. This paper describes one approach to protecting human health from pollutants which can also be accomplished in the coming years; the authors aim to provide an overview of smog alarm systems to experts and citizens in Central and Eastern European cities so that they can consider the option of building such systems in their own cities. To the authors' knowledge, this is the first review of its kind, and it is hoped that it will lead to a closer examination of this practical and effective control strategy

Emergency Air Protection: Implementing Smog Alarm Systems in Central and Eastern Europe

The first alarm system for summer smog was established in 1948 in Los Angeles. Following the tragic London Smog where several hundred people died, the Rhine-Ruhr area set up a winter smog alarm system in the early 1960s. Since that time, many industrialized countries have instituted smog-alarm systems, which have contributed to the reduction of air pollution risks to the public. Perhaps more importantly, these systems have stimulated progress in air pollution abatement technologies, since the costs of closing down industries during smog episodes is often higher than the necessary investments to reduce air pollution. Today, most countries with smog alarm systems have very infrequent air pollution episodes. The situation is different in industrially developing countries, where serious air pollution episodes are frequent. These countries may need to institute smog alarm systems to protect public health. For this reason, the Regional Environmental Center for Central and Eastern Europe asked IIASA to carry out a study that would help C&E European countries establish their own systems in collaboration with their neighbors. This report describes experience with winter and summer smog-alarm systems in western countries and makes recommendations for the design of cost-efficient and effective systems for C&E Europe. The Study was carried out in close collaboration with experts in these countries. We hope this report is helpful in assuring that, within a few years, efficient smog alarm systems are in place within the entire C&E European region. Moreover, we hope the information in this study is useful to other regions, in particular the Russian Republic, Ukraine, other states of the former Soviet Union, and also China, India, Brazil and newly industrializing countries

Le Corps Propre

Le Corpse Propre, is a series of large scaled paintings; performative archaeological stripteases through which layers of material stratigraphy reveal themselves through a deliberate process of revealing and concealing

Non-Iterative Joint Channel Equalisation and Channel Decoding

A non-iterative turbo equaliser scheme is proposed, which outperforms the iterative turbo equaliser by about 0.7 dB at a BER of 10E-3 over a symbol-spaced two-path channel and by about 3.4dB at a BER of 10e-3 over a five-path Gaussian channel

Engineering of III-Nitride Semiconductors on Low Temperature Co-fired Ceramics

This work presents results in the feld of advanced substrate solutions in order to achieve high crystalline quality group-III nitrides based heterostructures for high frequency and power devices or for sensor applications. With that objective, Low Temperature Co-fred Ceramics has been used, as a noncrystalline substrate. Structures like these have never been developed before, and for economic reasons will represent a groundbreaking material in these felds of Electronic. In this sense, the report presents the characterization through various techniques of three series of specimens where GaN was deposited on this ceramic composite, using diferent bufer layers, and a singular metal-organic chemical vapor deposition related technique for low temperature deposition. Other single crystalline ceramic-based templates were also utilized as substrate materials, for comparison purposes

dSAP18 and dHDAC1 contribute to the functional regulation of the Drosophila Fab-7 element

It was described earlier that the Drosophila GAGA factor [Trithorax-like (Trl)] interacts with dSAP18, which, in mammals, was reported to be a component of the Sin3–HDAC co-repressor complex. GAGA–dSAP18 interaction was proposed to contribute to the functional regulation of the bithorax complex (BX-C). Here, we show that mutant alleles of Trl, dsap18 and drpd3/hdac1 enhance A6-to-A5 transformation indicating a contribution to the regulation of Abd-B expression at A6. In A6, expression of Abd-B is driven by the iab-6 enhancer, which is insulated from iab-7 by the Fab-7 element. Here, we report that GAGA, dSAP18 and dRPD3/HDAC1 co-localize to ectopic Fab-7 sites in polytene chromosomes and that mutant Trl, dsap18 and drpd3/hdac1 alleles affect Fab-7-dependent silencing. Consistent with these findings, chromatin immunoprecipitation analysis shows that, in Drosophila embryos, the endogenous Fab-7 element is hypoacetylated at histones H3 and H4. These results indicate a contribution of GAGA, dSAP18 and dRPD3/HDAC1 to the regulation of Fab-7 function

The Enhancer of Trithorax and Polycomb Corto Interacts with Cyclin G in Drosophila

BACKGROUND: Polycomb (PcG) and trithorax (trxG) genes encode proteins involved in the maintenance of gene expression patterns, notably Hox genes, throughout development. PcG proteins are required for long-term gene repression whereas TrxG proteins are positive regulators that counteract PcG action. PcG and TrxG proteins form large complexes that bind chromatin at overlapping sites called Polycomb and Trithorax Response Elements (PRE/TRE). A third class of proteins, so-called "Enhancers of Trithorax and Polycomb" (ETP), interacts with either complexes, behaving sometimes as repressors and sometimes as activators. The role of ETP proteins is largely unknown. METHODOLOGY/PRINCIPAL FINDINGS: In a two-hybrid screen, we identified Cyclin G (CycG) as a partner of the Drosophila ETP Corto. Inactivation of CycG by RNA interference highlights its essential role during development. We show here that Corto and CycG directly interact and bind to each other in embryos and S2 cells. Moreover, CycG is targeted to polytene chromosomes where it co-localizes at multiple sites with Corto and with the PcG factor Polyhomeotic (PH). We observed that corto is involved in maintaining Abd-B repression outside its normal expression domain in embryos. This could be achieved by association between Corto and CycG since both proteins bind the regulatory element iab-7 PRE and the promoter of the Abd-B gene. CONCLUSIONS/SIGNIFICANCE: Our results suggest that CycG could regulate the activity of Corto at chromatin and thus be involved in changing Corto from an Enhancer of TrxG into an Enhancer of PcG

Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells

Arthur Manuscript date: 2010 October 9Polycomb group (PcG) proteins exert essential functions in the most disparate biological processes. The contribution of PcG proteins to cell commitment and differentiation relates to their ability to repress transcription of developmental regulators in embryonic stem (ES) cells and in committed cell lineages, including skeletal muscle cells (SMC). PcG proteins are preferentially removed from transcribed regions, but the underlying mechanisms remain unclear. Here, PcG proteins are found to occupy and repress transcription from an intronic region containing the microRNA miR-214 in undifferentiated SMC. Differentiation coincides with PcG disengagement, recruitment of the developmental regulators MyoD and myogenin, and activation of miR-214 transcription. Once transcribed, miR-214 negatively feeds back on PcG by targeting the Ezh2 3′UTR, the catalytic subunit of the PRC2 complex. miR-214-mediated Ezh2 protein reduction accelerates SMC differentiation and promotes unscheduled transcription of developmental regulators in ES cells. Thus, miR-214 and Ezh2 establish a regulatory loop controlling PcG-dependent gene expression during differentiation.National Institute of Arthritis and Musculoskeletal and Skin Diseases (U.S.) (Intramural Research Program