4,427 research outputs found

    Pascalammetry with operando microbattery probes: Sensing high stress in solid-state batteries.

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    Energy storage science calls for techniques to elucidate ion transport over a range of conditions and scales. We introduce a new technique, pascalammetry, in which stress is applied to a solid-state electrochemical device and induced faradaic current transients are measured and analyzed. Stress-step pascalammetry measurements are performed on operando microbattery probes (Li2O/Li/W) and Si cathodes, revealing stress-assisted Li+ diffusion. We show how non-Cottrellian lithium diffusional kinetics indicates stress, a prelude to battery degradation. An analytical solution to a diffusion/activation equation describes this stress signature, with spatiotemporal characteristics distinct from Cottrell's classic solution for unstressed systems. These findings create an unprecedented opportunity for quantitative detection of stress in solid-state batteries through the current signature. Generally, pascalammetry offers a powerful new approach to study stress-related phenomena in any solid-state electrochemical system

    Phase transition between d-wave and anisotropic s-wave gaps in high temperature oxides superconductors

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    We study models for superconductivity with two interactions: V>V^> due to antiferromagnetic(AF) fluctuations and V<V^< due to phonons, in a weak coupling approach to the high temperature superconductivity. The nature of the two interactions are considerably different; V>V^> is positive and sharply peaked at (±π\pm\pi,±π \pm\pi) while V<V^< is negative and peaked at (0,00,0) due to weak phonon screening. We numerically find (a) weak BCS attraction is enough to have high critical temperature if a van Hove anomaly is at work, (b) V>V^> (AF) is important to give d-wave superconductivity, (c) the gap order parameter Δ(k)\Delta({\bf k}) is constant(s-wave) at extremely overdope region and it changes to anisotropic s-wave as doping is reduced, (d) there exists a first order phase transition between d-wave and anisotropic s-wave gaps. These results are qualitatively in agreement with preceding works; they should be modified in the strongly underdope region by the presence of antiferromagnetic fluctuations and ensuing AF pseudogap.Comment: 4 pages in RevTex (double column), 4 figure

    Analysis of Laser ARPES from Bi2_2Sr2_2CaCu2_2O8+δ_{8+\delta} in superconductive state: angle resolved self-energy and fluctuation spectrum

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    We analyze the ultra high resolution laser angle resolved photo-emission spectroscopy (ARPES) intensity from the slightly underdoped Bi2_2Sr2_2CaCu2_2O8+δ_{8+\delta} in the superconductive (SC) state. The momentum distribution curves (MDC) were fitted at each energy \w employing the SC Green's function along several cuts perpendicular to the Fermi surface with the tilt angle θ\theta with respect to the nodal cut. The clear observation of particle-hole mixing was utilized such that the complex self-energy as a function of ω\omega is directly obtained from the fitting. The obtained angle resolved self-energy is then used to deduce the Eliashberg function \alpha^2 F^{(+)}(\th,\w) in the diagonal channel by inverting the d-wave Eliashberg equation using the maximum entropy method. Besides a broad featureless spectrum up to the cutoff energy ωc\omega_c, the deduced α2F\alpha^2 F exhibits two peaks around 0.05 eV and 0.015 eV. The former and the broad feature are already present in the normal state, while the latter emerges only below TcT_c. Both peaks become enhanced as TT is lowered or the angle th\th moves away from the nodal direction. The implication of these findings are discussed.Comment: 7 pages, 5 figures, summited to PR

    Recombinant monovalent llama-derived antibody fragments (VHH) to rotavirus VP6 protect neonatal gnotobiotic piglets against human rotavirus-induced diarrhea

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    Group A Rotavirus (RVA) is the leading cause of severe diarrhea in children. The aims of the present study were to determine the neutralizing activity of VP6-specific llama-derived single domain nanoantibodies (VHH nanoAbs) against different RVA strains in vitro and to evaluate the ability of G6P[1] VP6-specific llama-derived single domain nanoantibodies (VHH) to protect against human rotavirus in gnotobiotic (Gn) piglets experimentally inoculated with virulent Wa G1P[8] rotavirus. Supplementation of the daily milk diet with 3B2 VHH clone produced using a baculovirus vector expression system (final ELISA antibody -Ab- titer of 4096; virus neutralization -VN- titer of 256) for 9 days conferred full protection against rotavirus associated diarrhea and significantly reduced virus shedding. The administration of comparable levels of porcine IgG Abs only protected 4 out of 6 of the animals from human RVA diarrhea but significantly reduced virus shedding. In contrast, G6P[1]-VP6 rotavirus-specific IgY Abs purified from eggs of hyperimmunized hens failed to protect piglets against human RVA-induced diarrhea or virus shedding when administering similar quantities of Abs. The oral administration of VHH nanoAb neither interfered with the host's isotype profiles of the Ab secreting cell responses to rotavirus, nor induced detectable host Ab responses to the treatment in serum or intestinal contents. This study shows that the oral administration of rotavirus VP6-VHH nanoAb is a broadly reactive and effective treatment against rotavirus-induced diarrhea in neonatal pigs. Our findings highlight the potential value of a broad neutralizing VP6-specific VHH nanoAb as a treatment that can complement or be used as an alternative to the current strain-specific RVA vaccines. Nanobodies could also be scaled-up to develop pediatric medication or functional food like infant milk formulas that might help treat RVA diarrhea.Fil: Vega, Celina Guadalupe. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bok, Marina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Vlasova, Anastasia N.. Ohio State University; Estados UnidosFil: Chattha, Kuldeep S.. Ohio State University; Estados UnidosFil: Gómez Sebastián, Silvia. Universidad Politécnica de Madrid; EspañaFil: Nuñez, Carmen. Universidad Politécnica de Madrid; EspañaFil: Alvarado, Carmen. Universidad Politécnica de Madrid; EspañaFil: Lasa, Rodrigo. Universidad Politécnica de Madrid; EspañaFil: Escribano, José M.. Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Departamento Mejora Genética y Biotecnología; EspañaFil: Garaicoechea, Lorena Laura. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Fernández, Fernando. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Bok, Karin. National Institutes of Health; Estados UnidosFil: Wigdorovitz, Andrés. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Saif, Linda J.. Ohio State University; Estados UnidosFil: Parreño, Gladys Viviana. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

    Analyse de la variabilité germinative de la vesce commune sous l’impact d’un stress Ferrique-Cadmique-Salin

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    Ce travail a pour but de voir l’impact de l’application d’une combinaison de stress abiotique sur la germination des graines de vesce commune ainsi que de visualiser les modifications physiologiques et histologiques au niveau des tissus racinaires sous l’influence de ces contraintes. De ce fait, une conduite de germination a été réalisée avec des graines de vesce commune dans différentes situations de combinaisons entre trois types de stress métallique-cadmique-salin et un suivi a été fait en se basant sur des caractères végétatifs bien déterminés. Les résultats montrent bien une nette différence entre les réponses des graines à l’application de stress séparément et entre les combinaisons de stress ainsi qu’une variabilité intra-espèce énorme vis-à-vis de différentes types de contraintes.Mots-clés : vesce commune, stress métallique-cadmique-salin, caractères végétatifs, modifications physiologiques et histologiques

    Argentinean agid test for diagnosis of equine infectious anemia: six years of history

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    Equine infectious anemia (EIA) is a disease of high economic impact on the equine industry worldwide. Since horses are frequent travelers, EIA falls under strict regulatory control programs in many countries. In Argentina the national animal health authority (SENASA) states that all horses imported, moving within the country, or congregating at public assemblies must have a negative EIA report conducted within the previous 2 months. The agent causing EIA is a RNA virus from the Retroviridae family and its major capsid protein named p26 is the most immunogenic protein in the viral particle. Thus, the detection of specific antibodies directed to p26 is the aim of most diagnosis tests available in the world. The agar gel immunodifusion (AGID) is the officially accepted method to certify the diagnosis of EIA in Argentina. Since 2009 IncuINTA was working on the scaling up and production of the KIT AIE IDGA RP26, an Argentinean AGID test entirely developed in the laboratory containing a recombinant p26 protein to detect EIA antibodies in horses’ serum. Until 2015 IncuINTA produced two pilot batches and six commercial batches (one per year) containing from 24000 determinations in 2011 to 39600 determinations in 2015. Since the product was launched in 2011, the sales were increased 109%. Up to date we have placed on the market 170640 determinations. As expected, the number of laboratories buying the KIT AIE IDGA RP26 was also increasing through time being 26 in 2011 and 36 in 2015. This number of clients represents 17% of the 207 laboratories authorized by SENASA to diagnose EIA in Argentina. These laboratories are located mostly in Buenos Aires, Santa Fe, Entre Ríos, Formosa, La Pampa, Rio Negro, Cordoba, Corrientes, Salta and Tucum an provinces. Until 2009 there was no Argentinean EIA test available in our market being the imported ones very expensive. IncuINTA, which is a R&D laboratory, could scale up, produce and sell the KIT AIE IDGA RP26 during six consecutive years. After this success, IncuINTA perspective is to increase the number of batches each year to be able to attend the demand of most diagnosis laboratories in the country.Fil: Bok, Marina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Asenzo, G.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Vena, M. M.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Parreño, V.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Wigdorovitz, A.. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina10th International Equine Infectious Diseases ConferenceBuenos AiresArgentinaUniversity of Kentuck

    Deep Depth From Focus

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    Depth from focus (DFF) is one of the classical ill-posed inverse problems in computer vision. Most approaches recover the depth at each pixel based on the focal setting which exhibits maximal sharpness. Yet, it is not obvious how to reliably estimate the sharpness level, particularly in low-textured areas. In this paper, we propose `Deep Depth From Focus (DDFF)' as the first end-to-end learning approach to this problem. One of the main challenges we face is the hunger for data of deep neural networks. In order to obtain a significant amount of focal stacks with corresponding groundtruth depth, we propose to leverage a light-field camera with a co-calibrated RGB-D sensor. This allows us to digitally create focal stacks of varying sizes. Compared to existing benchmarks our dataset is 25 times larger, enabling the use of machine learning for this inverse problem. We compare our results with state-of-the-art DFF methods and we also analyze the effect of several key deep architectural components. These experiments show that our proposed method `DDFFNet' achieves state-of-the-art performance in all scenes, reducing depth error by more than 75% compared to the classical DFF methods.Comment: accepted to Asian Conference on Computer Vision (ACCV) 201
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