674 research outputs found
The effect of thermal annealing on the properties of Al-AlOx-Al single electron tunneling transistors
The effect of thermal annealing on the properties of Al-AlOx-Al single
electron tunneling transistors is reported. After treatment of the devices by
annealing processes in forming gas atmosphere at different temperatures and for
different times, distinct and reproducible changes of their resistance and
capacitance values were found. According to the temperature regime, we observed
different behaviors as regards the resistance changes, namely the tendency to
decrease the resistance by annealing at T = 200 degree C, but to increase the
resistance by annealing at T = 400 degree C. We attribute this behavior to
changes in the aluminum oxide barriers of the tunnel junctions. The good
reproducibility of these effects with respect to the changes observed allows
the proper annealing treatment to be used for post-process tuning of tunnel
junction parameters. Also, the influence of the annealing treatment on the
noise properties of the transistors at low frequency was investigated. In no
case did the noise figures in the 1/f-regime show significant changes.Comment: 6 pages, 7 eps-figure
Single-parameter non-adiabatic quantized charge pumping
Controlled charge pumping in an AlGaAs/GaAs gated nanowire by
single-parameter modulation is studied experimentally and theoretically.
Transfer of integral multiples of the elementary charge per modulation cycle is
clearly demonstrated. A simple theoretical model shows that such a quantized
current can be generated via loading and unloading of a dynamic quasi-bound
state. It demonstrates that non-adiabatic blockade of unwanted tunnel events
can obliterate the requirement of having at least two phase-shifted periodic
signals to realize quantized pumping. The simple configuration without multiple
pumping signals might find wide application in metrological experiments and
quantum electronics.Comment: 4 pages, 4 figure
Magnetization reversal of an individual exchange biased permalloy nanotube
We investigate the magnetization reversal mechanism in an individual
permalloy (Py) nanotube (NT) using a hybrid magnetometer consisting of a
nanometer-scale SQUID (nanoSQUID) and a cantilever torque sensor. The Py NT is
affixed to the tip of a Si cantilever and positioned in order to optimally
couple its stray flux into a Nb nanoSQUID. We are thus able to measure both the
NT's volume magnetization by dynamic cantilever magnetometry and its stray flux
using the nanoSQUID. We observe a training effect and temperature dependence in
the magnetic hysteresis, suggesting an exchange bias. We find a low blocking
temperature K, indicating the presence of a thin
antiferromagnetic native oxide, as confirmed by X-ray absorption spectroscopy
on similar samples. Furthermore, we measure changes in the shape of the
magnetic hysteresis as a function of temperature and increased training. These
observations show that the presence of a thin exchange-coupled native oxide
modifies the magnetization reversal process at low temperatures. Complementary
information obtained via cantilever and nanoSQUID magnetometry allows us to
conclude that, in the absence of exchange coupling, this reversal process is
nucleated at the NT's ends and propagates along its length as predicted by
theory.Comment: 8 pages, 4 figure
Minimally invasive reconstruction of lateral tibial plateau fractures using the jail technique: a biomechanical study
Background: This study described a novel, minimally invasive reconstruction technique of lateral tibial plateau fractures using a three-screw jail technique and compared it to a conventional two-screw osteosynthesis technique. The benefit of an additional screw implanted in the proximal tibia from the anterior at an angle of 90° below the conventional two-screw reconstruction after lateral tibial plateau fracture was evaluated. This new method was called the jail technique. Methods: The two reconstruction techniques were tested using a porcine model (n = 40). Fracture was simulated using a defined osteotomy of the lateral tibial plateau. Load-to-failure and multiple cyclic loading tests were conducted using a material testing machine. Twenty tibias were used for each reconstruction technique, ten of which were loaded in a load-to-failure protocol and ten cyclically loaded (5000 times) between 200 and 1000 N using a ramp protocol. Displacement, stiffness and yield load were determined from the resulting load displacement curve. Failure was macroscopically documented. Results: In the load-to-failure testing, the jail technique showed a significantly higher mean maximum load (2275.9 N) in comparison to the conventional reconstruction (1796.5 N, p 0.05). In cyclic testing, the jail technique also showed better trends in displacement that were not statistically significant. Failure modes showed a tendency of screws cutting through the bone (cut-out) in the conventional reconstruction. No cut-out but a bending of the lag screws at the site of the additional third screw was observed in the jail technique. Conclusions: The results of this study indicate that the jail and the conventional technique have seemingly similar biomechanical properties. This suggests that the jail technique may be a feasible alternative to conventional screw osteosynthesis in the minimally invasive reconstruction of lateral tibial plateau fractures. A potential advantage of the jail technique is the prevention of screw cut-outs through the cancellous bone.<br
Superconducting quantum interference devices with submicron Nb/HfTi/Nb junctions for investigation of small magnetic particles
We investigated, at temperature , electric transport, flux
noise and resulting spin sensitivity of miniaturized Nb direct current
superconducting quantum interference devices (SQUIDs) based on submicron
Josephson junctions with HfTi barriers. The SQUIDs are either of the
magnetometer-type or gradiometric in layout. In the white noise regime, for the
best magnetometer we obtain a flux noise
, corresponding to a
spin sensitivity . For the
gradiometer we find
and . The devices can still be
optimized with respect to flux noise and coupling between a magnetic particle
and the SQUID, leaving room for further improvement towards single spin
resolution.Comment: 4 pages, 3 figure
Electron Counting Capacitance Standard with an improved five-junction R-pump
The Electron Counting Capacitance Standard currently pursued at PTB aims to
close the Quantum Metrological Triangle with a final precision of a few parts
in 10^7. This paper reports the considerable progress recently achieved with a
new generation of single-electron tunnelling devices. A five-junction R-pump
was operated with a relative charge transfer error of five electrons in 10^7,
and was used to successfully perform single-electron charging of a cryogenic
capacitor. The preliminary result for the single-electron charge quantum has an
uncertainty of less than two parts in 10^6 and is consistent with the value of
the elementary charge.Comment: 16 pages, 9 figures, 1 tabl
Acoustically driven storage of light in a quantum well
The strong piezoelectric fields accompanying a surface acoustic wave on a
semiconductor quantum well structure are employed to dissociate optically
generated excitons and efficiently trap the created electron hole pairs in the
moving lateral potential superlattice of the sound wave. The resulting spatial
separation of the photogenerated ambipolar charges leads to an increase of the
radiative lifetime by orders of magnitude as compared to the unperturbed
excitons. External and deliberate screening of the lateral piezoelectric fields
triggers radiative recombination after very long storage times at a remote
location on the sample.Comment: 4 PostScript figures included, Physical Review Letters, in pres
A Y2H-seq approach defines the human protein methyltransferase interactome
To accelerate high-density interactome mapping, we developed a yeast two-hybrid interaction screening approach involving short-read second-generation sequencing (Y2H-seq) with improved sensitivity and a quantitative scoring readout allowing rapid interaction validation. We applied Y2H-seq to investigate enzymes involved in protein methylation, a largely unexplored post-translational modification. The reported network of 523 interactions involving 22 methyltransferases or demethylases is comprehensively annotated and validated through coimmunoprecipitation experiments and defines previously undiscovered cellular roles of nonhistone protein methylation
Sex differences in clinical characteristics and outcomes in patients undergoing heart transplantation
Aims: Whether sex affects selection for and outcomes after heart transplantation (HTx) remains unclear. We aimed to show sex differences in pre‐transplant characteristics and outcomes after HTx. Methods and results: From 1995 to 2019, 49 200 HTx recipients were prospectively enrolled in the Organ Procurement and Transplantation Network. Logistic regression models were used to evaluate clinical characteristics by sex. Multivariable Cox regression models were fitted to assess sex differences in all‐cause mortality, cardiovascular mortality, graft failure, cardiac allograft vasculopathy (CAV), and malignancy. In 49 200 patients (median age 55 years, interquartile range 46–62; 24.6% women), 49 732 events occurred during a median follow‐up of 8.1 years. Men were older than women, had more often ischaemic cardiomyopathy (odds ratio [OR] 3.26, 95% confidence interval [CI] 3.11–3.42; P < 0.001), and a higher burden of cardiovascular risk factors, whereas women had less malignancies (OR 0.47, CI 0.44–0.51; P < 0.001). Men were more often treated in intensive care unit (OR 1.24, CI 1.12–1.37; P < 0.001) with a higher need for ventilatory (OR 1.24, CI 1.17–1.32; P < 0.001) or VAD (OR 1.53, CI 1.45–1.63; P < 0.001) support. After multivariable adjustment, men had a higher risk for CAV (hazard ratio [HR] 1.21, CI 1.13–1.29; P < 0.001) and malignancy (HR 1.80, CI 1.62–2.00; P < 0.001). There were no differences in all‐cause mortality, cardiovascular mortality, and graft failure between sexes. Conclusions: In this US transplant registry, men and women differed in pre‐transplant characteristics. Male sex was independently associated with incident CAV and malignancy even after multivariable adjustment. Our results underline the need for better personalized post‐HTx management and care
Photoluminescence investigations of 2D hole Landau levels in p-type single Al_{x}Ga_{1-x}As/GaAs heterostructures
We study the energy structure of two-dimensional holes in p-type single
Al_{1-x}Ga_{x}As/GaAs heterojunctions under a perpendicular magnetic field.
Photoluminescence measurments with low densities of excitation power reveal
rich spectra containing both free and bound-carrier transitions. The
experimental results are compared with energies of valence-subband Landau
levels calculated using a new numerical procedure and a good agreement is
achieved. Additional lines observed in the energy range of free-carrier
recombinations are attributed to excitonic transitions. We also consider the
role of many-body effects in photoluminescence spectra.Comment: 13 pages, 10 figures, accepted to Physical Review
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