347 research outputs found
Legal problems of the corruption prevention in state and municipal health care institutions
The purpose of the research: to investigate the problems of legal regulation of the corruption prevention in health care institutions, outline ways of their solution.
Materials and methods: normative-legal base of Ukraine, method of analysis, method of synthesis, comparative-legal method.
Results: The issues of the corruption prevention, including its prevention in health care institutions, are regulated by a number of normative legal acts, in particular the Law of Ukraine "About Corruption Prevention", the Code of Ukraine on Administrative Offenses, and the Criminal Code of Ukraine. However, a number of norms are collisional, therefore they need legal improvement.
Conclusions: One of the main problems of the corruption prevention is the formation of a unified normative approach to the legal regulation of the health care institutions financing, which is to bring in compliance all other normative legal acts regulating these issues with the Constitution of Ukraine or changing the Constitution. The requirements of the Criminal Code of Ukraine, the Labor Code of Ukraine, and the Civil Code of Ukraine require alignment with the Law of Ukraine "About Corruption Prevention". It is necessary to legislatively define mechanisms for the protection of the rights of officials, in particular the right to extract information about a person from the Unified State Register of persons who committed corruption or corruption-related offenses in the event of the expiration of the period provided for by the Code of Ukraine on Administrative Offenses and the Labor Code of Ukraine after the end of which the person is considered to be not attracted to a certain type of responsibility. The urgent need is to increase social standards for health workers. The need for significant improvement of the notion and settlement of the conflict of interests in accordance with the current legislation is dictated by the threat of bringing this legal institution to the point of absurdity. And, of course, strengthening legal education and legal work with patients and health care providers, maximizing the openness of information is an effective prevention of corruption manifestations
Prospective development of legal education in the field of health care as a guarantee of medical reform implementation in Ukraine
The purpose of the research: explore legal issues and the need for professional growth of health care workers towards the formation of legal competencies in the context of medical reform in Ukraine, identify promising ways for the development of legal education in health care.
Materials and methods: normative-legal base of Ukraine, method of analysis, method of synthesis, comparative-legal and structural-functional methods.
Results. The need for further development of legal education for healthcare workers stems from a detailed analysis of the regulatory and legal acts of Ukraine regulating medical and pharmaceutical activities, in particular, the Constitution of Ukraine, the Criminal Code of Ukraine, the Code of Ukraine on Administrative Offenses, the Laws of Ukraine “Fundamentals of the Legislation of Ukraine on Health Care”, “On State Financial Guarantees of Medical Care of the Population”, “On Amendments to Certain Legislative Acts of Ukraine regarding the improvement of legislation on the activities of health care institutions”, “On the prevention of corruption”, the decree of the Cabinet of Ministers of Ukraine “On approval of the competition for the position of head of state, municipal health care institutions”, order of the Ministry of Health of Ukraine from 31.10.2018 № 1977 “On Amendments to the Handbook of qualification characteristics of workers occupations”. Issue 78 “Health” and many others. Societies of public authorities, researchers, educators, medical, pharmaceutical workers and patients need to comprehend deeply the processes of modern transformation in the health sector, its legal regulation and the associated innovative approach to the competence matrix of the modern health worker, to develop a unified approach to the development of methods and forms of legal education in health care.
Conclusions. In order to improve the effectiveness of legal education, it is necessary to develop and approve by the Resolution of the Cabinet of Ministers of Ukraine the National Concept for the Development of Legal Education in Healthcare, which should cover all subjects of legal relations in health care, including public authorities and local government, to provide the development of departments and pharmaceutical-legal and medical-legal teaching not only in medical and pharmaceutical, but also legal higher education institutions; a significant legal component of the training of health managers in master's programs; a mandatory component of medical, pharmaceutical and legal education for professionals and specialists in the field of health care at various levels and specialties. Anti-corruption education in the framework of continuing professional development of specialists should be a mandatory separate area of legal education
Principle of patient's autonomy: problems of legal regulation in Ukraine
The purpose of the research: to study the content of the principle of patient autonomy, the problem of its legal regulation in accordance with the legislation of Ukraine, outline the ways of their solution.
Materials and methods: the regulatory and legal framework of Ukraine, the method of analysis, the method of synthesis, the comparative legal method.
Results: The normative legal acts of Ukraine, in particular the Law of Ukraine “Fundamentals of Ukrainian legislation on health care”, the Civil Code of Ukraine, enshrined the principle of patient autonomy. However, a number of norms are conflict-related, so they need legal improvement.
Conclusions: The structure of the patient's autonomy principle includes the concept of informed consent and such basic rights of the patient as the right to choose a doctor, methods of treatment, and health facilities. At present, legislation that regulates the issue of consent of patients between 14 and 18 years of age, the refusal of medical intervention, the provision of complete information on the patient's health status, the right to choose a doctor and a health care institution, requires more precise changes, requires more precise regulation of the consent of the parents (or one from the parents) of the child to medical intervention
Two Scenarios of Breaking Chaotic Phase Synchronization
Two types of phase synchronization (accordingly, two scenarios of breaking
phase synchronization) between coupled stochastic oscillators are shown to
exist depending on the discrepancy between the control parameters of
interacting oscillators, as in the case of classical synchronization of
periodic oscillators. If interacting stochastic oscillators are weakly detuned,
the phase coherency of the attractors persists when phase synchronization
breaks. Conversely, if the control parameters differ considerably, the chaotic
attractor becomes phase-incoherent under the conditions of phase
synchronization break.Comment: 8 pages, 7 figure
Synchronization of chaotic oscillator time scales
This paper deals with the chaotic oscillator synchronization. A new approach
to detect the synchronized behaviour of chaotic oscillators has been proposed.
This approach is based on the analysis of different time scales in the time
series generated by the coupled chaotic oscillators. It has been shown that
complete synchronization, phase synchronization, lag synchronization and
generalized synchronization are the particular cases of the synchronized
behavior called as "time--scale synchronization". The quantitative measure of
chaotic oscillator synchronous behavior has been proposed. This approach has
been applied for the coupled Rossler systems.Comment: 29 pages, 11 figures, published in JETP. 100, 4 (2005) 784-79
Effective Fokker-Planck Equation for Birhythmic Modified van der Pol Oscillator
We present an explicit solution based on the phase-amplitude approximation of
the Fokker-Planck equation associated with the Langevin equation of the
birhythmic modified van der Pol system. The solution enables us to derive
probability distributions analytically as well as the activation energies
associated to switching between the coexisting different attractors that
characterize the birhythmic system. Comparing analytical and numerical results
we find good agreement when the frequencies of both attractors are equal, while
the predictions of the analytic estimates deteriorate when the two frequencies
depart. Under the effect of noise the two states that characterize the
birhythmic system can merge, inasmuch as the parameter plane of the birhythmic
solutions is found to shrink when the noise intensity increases. The solution
of the Fokker-Planck equation shows that in the birhythmic region, the two
attractors are characterized by very different probabilities of finding the
system in such a state. The probability becomes comparable only for a narrow
range of the control parameters, thus the two limit cycles have properties in
close analogy with the thermodynamic phases
Global stability analysis of birhythmicity in a self-sustained oscillator
We analyze global stability properties of birhythmicity in a self-sustained
system with random excitations. The model is a multi-limit cycles variation of
the van der Pol oscillatorintroduced to analyze enzymatic substrate reactions
in brain waves. We show that the two frequencies are strongly influenced by the
nonlinear coefficients and . With a random excitation, such as
a Gaussian white noise, the attractor's global stability is measured by the
mean escape time from one limit-cycle. An effective activation energy
barrier is obtained by the slope of the linear part of the variation of the
escape time versus the inverse noise-intensity 1/D. We find that the
trapping barriers of the two frequencies can be very different, thus leaving
the system on the same attractor for an overwhelming time. However, we also
find that the system is nearly symmetric in a narrow range of the parameters.Comment: 17 pages, 8 figures, to appear on Choas, 201
Bimodality and hysteresis in systems driven by confined L\'evy flights
We demonstrate occurrence of bimodality and dynamical hysteresis in a system
describing an overdamped quartic oscillator perturbed by additive white and
asymmetric L\'evy noise. Investigated estimators of the stationary probability
density profiles display not only a turnover from unimodal to bimodal character
but also a change in a relative stability of stationary states that depends on
the asymmetry parameter of the underlying noise term. When varying the
asymmetry parameter cyclically, the system exhibits a hysteresis in the
occupation of a chosen stationary state.Comment: 4 pages, 5 figures, 30 reference
Resonant enhancement of the jump rate in a double-well potential
We study the overdamped dynamics of a Brownian particle in the double-well
potential under the influence of an external periodic (AC) force with zero
mean. We obtain a dependence of the jump rate on the frequency of the external
force. The dependence shows a maximum at a certain driving frequency. We
explain the phenomenon as a switching between different time scales of the
system: interwell relaxation time (the mean residence time) and the intrawell
relaxation time. Dependence of the resonant peak on the system parameters,
namely the amplitude of the driving force A and the noise strength
(temperature) D has been explored. We observe that the effect is well
pronounced when A/D > 1 and if A/D 1 the enhancement of the jump rate can be of
the order of magnitude with respect to the Kramers rate.Comment: Published in J. Phys. A: Math. Gen. 37 (2004) 6043-6051; 6 figure
Zebrafish, a novel model system to study uremic toxins: The case for the sulfur amino acid lanthionine
The non-proteinogenic amino acid lanthionine is a byproduct of hydrogen sulfide biosynthesis: the third endogenous vasodilator gas, after nitric oxide and carbon monoxide. While hydrogen sulfide is decreased in uremic patients on hemodialysis, lanthionine is increased and has been proposed as a new uremic toxin, since it is able to impair hydrogen sulfide production in hepatoma cells. To characterize lanthionine as a uremic toxin, we explored its effects during the early development of the zebrafish (Danio rerio), a widely used model to study the organ and tissue alterations induced by xenobiotics. Lanthionine was employed at concentrations reproducing those previously detected in uremia. Light-induced visual motor response was also studied by means of the DanioVision system. Treatment of zebrafish embryos with lanthionine determined acute phenotypical alterations, on heart organogenesis (disproportion in cardiac chambers), increased heart beating, and arrhythmia. Lanthionine also induced locomotor alterations in zebrafish embryos. Some of these effects could be counteracted by glutathione. Lanthionine exerted acute effects on transsulfuration enzymes and the expression of genes involved in inflammation and metabolic regulation, and modified microRNA expression in a way comparable with some alterations detected in uremia. Lanthionine meets the criteria for classification as a uremic toxin. Zebrafish can be successfully used to explore uremic toxin effects
- …