Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

[This corrects the article DOI: 10.1186/s13054-016-1208-6.]

Contrast-enhanced sonographic detection of vesicoureteral reflux in children: Comparison with voiding cystourethrography

Purpose: Prospective evaluation of contrast-enhanced sonography (CES) as an alternative to radiographic voiding cystourethrography (VCUG) in the detection of vesicoureteral reflux (VUR). Materials and Methods: Seventy-six children (age range: 0-9 years, mean age 1.4 years) with suspicion of VUR due to various indications were examined by contrast-enhanced sonography (CES) and VCUG. CES examination was performed after instillation of Levovist into the catheterized urinary bladder, which had been prefilled with normal saline. Reflux was diagnosed when hyperechogenic microbubbles were observed in the renal units. Thereafter, VCUG was performed in all patients through the same catheter. CES findings were compared to the results of VCUG. Results: CES showed VUR in 24 renal units whereas VCUG showed reflux in 18 renal units. With regard to the presence of VUR, the findings obtained by both methods were concordant in 17 renal units. Taking VCUG as the reference standard, the sensitivity of CES was 96%, the specificity was 94.8%, the positive predictive value 77.4% and the negative predictive value 99.2%. Additionally, McNemar test showed that CES detected a statistically significant higher number of renal units with VUR (p < 0.05). Conclusion: It is suggested that CES is an accurate and reliable imaging modality for the detection of VUR, although it cannot replace VCUG in some cases. In addition, CES can be recommended in the follow-up of VUR, reducing the number of radiographic investigations

ACTIVAGE - D9.6 Final results report & sustainability plan (I to IX)

We have reached the end of a challenging and rewarding journey, after 45 months of ACTIVAGE, this is the last report that aims at providing a taste of the huge work done by the teams at the local sites. This is a testimony of the more than 45 partners that have participated in this WP. We started with 9 DS in 7 countries and we finish with 12 DS in 9 countries, having incorporated three new DS through the open call, and expanding ACTIVAGE vision and ecosystem to Portugal and Bulgaria. We have been able to reach the target of deploying AHA-IoT solutions for more than 7.200 users, we hit the mark of 7.776 and almost 97% of the expected deployments. All DS have been able to perform the evaluation, at local and global level, generating the evidence that ACTIVAGE vision is pertinent, relevant, and effective. Details are provided in the individual results and in D6.5. By the end of the project, still 80% of participants continue operation, and almost all DS have in place sustainability plans to continue providing ACTIVAGE services in one way or another. Even in the cases where no clear plans have been possible, there are opportunities for exploiting the services and the knowledge gained in the project