The Influence of Ottoman Empire on the conservation of the architectural heritage in Jerusalem

Jerusalem is one of the oldest cities in the world. It was built by the Canaanites in 3000 B.C., became the first Qiblaof Muslims and is the third holiest shrine after Mecca and Medina. It is believed to be the only sacred city in the world that is considered historically and spiritually significant to Muslims, Christians, and Jews alike. Since its establishment, the city had been subjected to a series of changes as the result of political, economic and social developments that affected the architectural formation through successive periods from the beginning leading up to the Ottoman Era, which then achieved relative stability. The research aims to examine and review the conservation mechanisms of the architectural buildings during the Ottomans rule in Jerusalem for more than 400 years, and how the Ottoman Sultans had contributed in revitalizing and protecting the city from loss and extinction. The researcher followed the historical interpretive method using descriptive analysis based on a literature review and preliminary study to determine Ottoman practices in conserving the historical and architectural heritage of Jerusalem. The research found that the Ottoman efforts towards conserving the architectural heritage in Jerusalem fell into four categories (Renovation, Restoration, Reconstruction and Rehabilitation). The Ottomans focused on the conservation of the existing buildings rather than new construction, because of their respect of local traditions and the holy places.Yerusalem adalah salah satu kota tertua di dunia. Dibangun oleh orang-orang Kanaan pada 3000 SM, kota ini menjadi kiblat pertama umat Islam dan merupakan tempat suci ketiga setelah Mekkah dan Madinah. Kota ini diyakini sebagai satu-satunya kota suci di dunia yang dianggap penting secara historis dan spiritual bagi umat Islam, Kristen, dan Yahudi. Sejak didirikan, kota ini telah mengalami serangkaian perubahan sebagai akibat dari perkembangan politik, ekonomi dan sosial yang memengaruhi pembentukan arsitektur melalui periode-periode berturut-turut dari awal menuju era Ottoman, yang kemudian mencapai stabilitas relatif. Penelitian ini bertujuan untuk menguji dan meninjau mekanisme konservasi bangunan arsitektur selama pemerintahan Ottoman di Yerusalem selama lebih dari 400 tahun, dan bagaimana Sultan Ottoman telah berkontribusi dalam merevitalisasi dan melindungi kota dari kehilangan dan kepunahan. Peneliti mengikuti metode interpretif historis dan analisis deskriptif berdasarkan tinjauan literatur dan studi pendahuluan untuk menentukan praktik Ottoman dalam melestarikan warisan sejarah dan arsitektur Yerusalem. Penelitian ini menemukan bahwa upaya Ottoman ke arah pelestarian warisan arsitektur di Yerusalem jatuh ke dalam empat kategori (Renovasi, Restorasi, Rekonstruksi dan Rehabilitasi). Ottoman berfokus pada konservasi bangunan yang ada daripada konstruksi baru, karena rasa hormat mereka terhadap tradisi lokal dan tempat-tempat suci.

Systematic review of brucellosis in the Middle East: disease frequency in ruminants and humans and risk factors for human infection

This paper considers the problem of finding global states incoming to a specified global state in a Boolean network, which may be useful for pre-processing of finding a sequence of control actions for a Boolean network and for identifying the basin of attraction for a given attractor, We show that this problem is NP-hard in general along with related theoretical results, On the other hand, we present algorithms that are much faster than the naive exhaustive search-based algorithm. ©2007 IEEE.link_to_subscribed_fulltex

Data Clustering Using Wave Atom

Clustering of huge spatial databases is an important issue which tries to track the densely regions in the feature space to be used in data mining, knowledge discovery, or efficient information retrieval. Clustering approach should be efficient and can detect clusters of arbitrary shapes because spatial objects cannot be simply abstracted as isolated points they have different boundary, size, volume, and location. In this paper we use discrete wave atom transformation technique in clustering to achieve more accurate result. By using multi-resolution transformation like wavelet and wave atom we can effectively identify arbitrary shape clusters at different degrees of accuracy. Experimental results on very large data sets show the efficiency and effectiveness of the proposed wave atom bases clustering approach compared to other recent clustering methods. Experimental result shows that we get more accurate result and denoised output than others

PHARMACEUTICAL QUALITY ASSESSMENT OF GLIMEPIRIDE TABLETS – COMPARISON OF BRANDS AND NEWLY FORMULATED TABLETS WITH INNOVATOR

Objective: The main objective of the study was to assess the quality attribute of generic brands and newly formulated tablet of glimepiride and compare their drug release profile with innovator brand. Methods: Different brands were purchased from different markets of UAE. The validated high-performance liquid chromatography method was used to assess the quantitative analysis of glimepiride. The linearity of curve (r² = 0.9999) indicated the accuracy and precision of the analytical method. Comparative dissolution of newly formulated and generic tablets was carried out using USP dissolution apparatus II. Study was accomplished in phosphate buffer (pH = 7.8), the paddle speed was adjusted at 75 rpm. F1 and F2 factor among the brands and kinetic assessment were done to obtain the order of release. Results: Dissolution profiles of formulated tablets were almost same as that of innovator, 91.53 and 94.9, respectively, in 15 min. The statistical value between the different brands (F = 3.698) indicated that there were some differences among the few groups of tablets and p-value (0.002154) indicated that it supported H1 hypothesis. First-order and Weibull models described the drug release with r2 value of 0.9981–0.927210 and 0.9992– 0.9835, respectively. Stability of optimized formulated batch was also examined. Conclusion: It was concluded that the formulated tablets are stable and pharmaceutically as good as the innovators; however, all the selected brands could not be used interchangeably in the clinical practice. It was also concluded that the scrutiny and screening of the drug products, available in the markets, can help to build a better health-care setup

Prevalence of Giardia Assemblages Among Equines in Jordan

A cross-sectional study was carried out on 400 equine holding (326 horses and 74 donkeys) samples to determine the prevalence of Giardia assemblages A, B, and E in Jordan. Identifying the Giardia assemblages was carried out using enzyme-linked immunosorbent assay (ELISA) as a screening test and PCR-RFLP targeting β-giardin loci. In addition, polymerase chain reaction targeting triose phosphate isomerase gene specific for assemblages A and B were used as confirmatory. Thirty-four samples tested positive by ELISA for Giardia with an apparent prevalence of 8.5%. The PCR-RFLP test confirmed Giardia assemblages in 30 of the 34 ELISA-positive samples giving a true prevalence of 7.7% (95% confidence interval: 4.8–10.1). Of the 30 positive animals/holdings, 18, 4, and 8 had assemblages A, B, and E. Assemblage A was significantly (P < .05) more prevalent when compared to assemblages B and E. The total infection rates of Giardia, assemblages B and E were significantly (P < .05, chi-square) higher in donkeys 14.8%, 2.7%, and 5.5% compared to horses 5.8%, 0.6%, and 1.2%, respectively. Analysis of risk factors revealed that only season was significantly associated with the different Giardia assemblages. Autumn (odds ratio [OR] = 0.09) was associated with Giardia infection regardless of the assemblage type as reducing factor. The odds of infection of assemblages A and E increased in winter (OR = 6.8) and spring (OR = 4.5), respectively. Giardia assemblages A, B, and E infect both horses and donkeys in Jordan with potential impact on human and animal health, and the odds of infections is significantly associated with season

A systematic review of sub-microscopic Plasmodium vivax infection.

BACKGROUND: An accurate estimate of Plasmodium vivax prevalence is essential for the successful implementation of malaria control and elimination programmes. Prevalence estimates both inform control strategies and are used in their evaluation. Light microscopy is the main method for detecting Plasmodium parasitaemia in the peripheral blood, but compared to molecular diagnostics, such as polymerase chain reaction (PCR), has limited sensitivity. METHODS: A systematic review and meta-analysis was conducted to assess the effect of detection method on the prevalence of P. vivax and to quantify the extent to which P. vivax infections are undetected by microscopy. Embase, Medline and the Cochrane Database were searched for studies reporting prevalence by PCR and by microscopy and that contained all of the following key words: vivax, PCR, and malaria. Prevalence estimates and study meta-data were extracted systematically from each publication. Combined microscopy:PCR prevalence ratios were estimated by random effects meta-analysis. Sensitivity and specificity of microscopy were calculated using PCR as the gold standard. RESULTS: Of 874 studies reviewed, 40 met the criteria for inclusion contributing 54 prevalence pairs. The prevalence of P. vivax infection measured by PCR was consistently higher than the prevalence measured by microscopy with sub-patent parasitaemia. The mean prevalence of infection detected by microscopy was 67 % (95 % CI 59-73 %) lower than the prevalence detected by PCR. The detection of sub-patent parasitaemia did not vary according to the microscopy method (thick or, thick and thin smears), the PCR prevalence (as a measure of the true P. vivax prevalence), the type of blood used or DNA extraction method. CONCLUSIONS: Quantifying P. vivax parasitaemia by PCR rather than microscopy consistently increased prevalence estimates by a factor of 2.3. Whilst the sensitivity of microscopy can be improved by better methods, molecular methods have potential to be scaled up to improve the detection of P. vivax transmission reservoirs