Abbas

Abo-Shehada

Akbarmehr

Al-Majali

Al-Shamahy

AL-Shamahy

Awad

Awwad

Banai

Behroozikhah

Darwish

Dawood

Dohoo

El-Amin

El-Seedy

F. J. GUITIAN

Goodwin

H. R. HOLT

Hawari

Husseini

I. I. MUSALLAM

Khadjeh

M. N. ABO-SHEHADA

McDermott

McGiven

Meky

Mohammed

Moustafa

Murray

Nada

Okello

Radwan

Shemesh

Shimol

Y. M. HEGAZY

Yawoz

Zowghi

English

Musallam, I I

Abo-Shehada, M N

Hegazy, Y M

Holt, H R

Guitian, J

RVC Research Online

Systematic review of brucellosis in the Middle East: disease frequency in ruminants and humans and risk factors for human infection

SUMMARYA systematic review of studies providing frequency estimates of brucellosis in humans and ruminants and risk factors forBrucellaspp. seropositivity in humans in the Middle East was conducted to collate current knowledge of brucellosis in this region. Eight databases were searched for peer-reviewed original Arabic, English, French and Persian journal articles; the search was conducted on June 2014. Two reviewers evaluated articles for inclusion based on pre-defined criteria. Of 451 research articles, only 87 articles passed the screening process and provided bacteriological and serological evidence for brucellosis in all Middle Eastern countries.Brucella melitensisandB. abortushave been identified in most countries in the Middle East, supporting the notion of widespread presence ofBrucellaspp. especiallyB. melitensisacross the region. Of the 87 articles, 49 were used to provide evidence of the presence ofBrucellaspp. but only 11 provided new knowledge on the frequency of brucellosis in humans and ruminants or on human risk factors for seropositivity and were deemed of sufficient quality. Small ruminant populations in the region show seroprevalence values that are among the highest worldwide. Human cases are likely to arise from subpopulations occupationally exposed to ruminants or from the consumption of unpasteurized dairy products. The Middle East is in need of well-designed observational studies that could generate reliable frequency estimates needed to assess the burden of disease and to inform disease control policies.</jats:p

Crossref

Epidemiology and Infection

https://researchonline.rvc.ac.uk/id/eprint/10081/1/10081.pdf

Systematic review of brucellosis in the Middle East: disease frequency in ruminants and humans and risk factors for human infection

Abstract

Similar works

Full text

Available Versions

RVC Research Online

Crossref