A low-cost vision based navigation system for small size unmanned aerial vehicle applications

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Active sound radiation control with secondary sources at the edge of the opening

© 2016 Elsevier Ltd Planar virtual sound barriers with secondary sources over the entire opening have been demonstrated an effective way to achieve global control of sound transmission through the opening, but loudspeakers in the middle of the opening affect ventilation, lighting and normal access through it. To avoid the problem, this technical note proposes to implement secondary sources at the edge of a cavity opening and investigates the active sound reduction performance of the system numerically and experimentally. Unlike secondary sources over the entire opening which can achieve sound reduction at any frequency as long as there are sufficient of them, there exists an upper bound of effective frequency for global control when secondary sources are at the edge of the opening; however, local control is always achievable. Preliminary experiments were conducted on an open wooden box and a semi-closed meeting room to support the conclusions

Thermophysiological comfort analysis of aerogel nanoparticle incorporated fabric for fire fighter's protective clothing

The paper discusses the thermophysiological comfort of a newly developed fabric potentially for firefighter's protective clothing. The fabrics were developed by incorporating super hydrophobic silica aerogel nanoparticles in 65/35 wool-Aramid blended fabric. Then the theromophysiological comfort was analyzed by determining air, moisture and heat transfer performance. It has been found that only 2% coating of aerogel nanoparticle increases thermal resistance by up to 68.64% and can reduce air permeability by up to 45.46% whereas 4% aerogel coating can reduce 61.76% air permeability. Moisture management properties of the aerogel coated fabric have also been investigated and discussed in details. In brief, it can be said that the thickener that was used for the coating, has a positive impact on moisture transportation and overall moisture management property of the fabric. Again aerogel coated next-to-skin layer and aerogel coated outer layer acted differently on the same fabric. It was observed that, the coated fabric acts as more likely as a moisture management fabric when the coating was applied on next-to-skin surface

A pseudo feedback-based annotated TF-IDF technique for dynamic crypto-ransomware pre-encryption boundary delineation and features extraction

The cryptography employed against user files makes the effect of crypto-ransomware attacks irreversible even after detection and removal. Thus, detecting such attacks early, i.e. during pre-encryption phase before the encryption takes place is necessary. Existing crypto-ransomware early detection solutions use a fixed time-based thresholding approach to determine the pre-encryption phase boundaries. However, the fixed time thresholding approach implies that all samples start the encryption at the same time. Such assumption does not necessarily hold for all samples as the time for the main sabotage to start varies among different crypto-ransomware families due to the obfuscation techniques employed by the malware to change its attack strategies and evade detection, which generates different attack behaviors. Additionally, the lack of sufficient data at the early phases of the attack adversely affects the ability of feature extraction techniques in early detection models to perceive the characteristics of the attacks, which, consequently, decreases the detection accuracy. Therefore, this paper proposes a Dynamic Pre-encryption Boundary Delineation and Feature Extraction (DPBD-FE) scheme that determines the boundary of the pre-encryption phase, from which the features are extracted and selected more accurately. Unlike the fixed thresholding employed by the extant works, DPBD-FE tracks the pre-encryption phase for each instance individually based on the first occurrence of any cryptography-related APIs. Then, an annotated Term Frequency-Inverse Document Frequency (aTF-IDF) technique was utilized to extract the features from runtime data generated during the pre-encryption phase of crypto-ransomware attacks. The aTF-IDF overcomes the challenge of insufficient attack patterns during the early phases of the attack lifecycle. The experimental evaluation shows that DPBD-FE was able to determine the pre-encryption boundaries and extract the features related to this phase more accurately compared to related works

Care Transitions From Patient and Caregiver Perspectives

PURPOSE: Despite concerted actions to streamline care transitions, the journey from hospital to home remains hazardous for patients and caregivers. Remarkably little is known about the patient and caregiver experience during care transitions, the services they need, or the outcomes they value. The aims of this study were to (1) describe patient and caregiver experiences during care transitions and (2) characterize patient and caregiver desired outcomes of care transitions and the health services associated with them. METHODS: We interviewed 138 patients and 110 family caregivers recruited from 6 health networks across the United States. We conducted 34 homogenous focus groups (103 patients, 65 caregivers) and 80 key informant interviews (35 patients, 45 caregivers). Audio recordings were transcribed and analyzed using principles of grounded theory to identify themes and the relationship between them. RESULTS: Patients and caregivers identified 3 desired outcomes of care transition services: (1) to feel cared for and cared about by medical providers, (2) to have unambiguous accountability from the health care system, and (3) to feel prepared and capable of implementing care plans. Five care transition services or provider behaviors were linked to achieving these outcomes: (1) using empathic language and gestures, (2) anticipating the patient\u27s needs to support self-care at home, (3) collaborative discharge planning, (4) providing actionable information, and (5) providing uninterrupted care with minimal handoffs. CONCLUSIONS: Clear accountability, care continuity, and caring attitudes across the care continuum are important outcomes for patients and caregivers. When these outcomes are achieved, care is perceived as excellent and trustworthy. Otherwise, the care transition is experienced as transactional and unsafe, and leaves patients and caregivers feeling abandoned by the health care system

Factors Associated with High Prevalence of Intestinal Protozoan Infections among Patients in Sana'a City, Yemen

Intestinal protozoan diseases in Yemen are a significant health problem with prevalence ranging from 18% to 27%. The present study is a cross-sectional study aimed at determining the factors associated with the high prevalence of intestinal protozoan infections among patients seeking health care in Sana'a City, the capital of Yemen. (0.4%). Multivariate analysis using forward stepwise logistic regression based on intestinal protozoan infections showed that contact with animals (OR = 1.748, 95% CI = 1.168–2.617) and taking bath less than twice a week (OR = 1.820, 95% CI = 1.192–2.779) were significant risk factors of protozoan infections. infections being most common. Statistical analysis indicated that low personal hygiene and contact with animals were important predictors for intestinal protozoan infections. As highlighted in this study, in order to effectively reduce these infections, a multi-sectoral effort is needed. Preventive measures should include good hygienic practices, good animal husbandry practices, heightened provision of educational health programs, health services in all governorates including rural areas. Furthermore, it is also essential to find radical solutions to the recent water crises in Yemen

Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.

Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability

Inhibition of protein ubiquitination by paraquat and 1-methyl-4-phenylpyridinium impairs ubiquitin-dependent protein degradation pathways

Intracytoplasmic inclusions of protein aggregates in dopaminergic cells (Lewy bodies) are the pathological hallmark of Parkinson’s disease (PD). Ubiquitin (Ub), alpha [α]-synuclein, p62/sequestosome 1 and oxidized proteins are major components of Lewy bodies. However, the mechanisms involved in the impairment of misfolded/oxidized protein degradation pathways in PD are still unclear. PD is linked to mitochondrial dysfunction and environmental pesticide exposure. In this work, we evaluated the effect of the pesticide paraquat (PQ) and the mitochondrial toxin 1-methyl-4-phenylpyridinium (MPP+) on Ub-dependent protein degradation pathways. No increase in the accumulation of Ub-bound proteins or aggregates was observed in dopaminergic cells (SK-N-SH) treated with PQ or MPP+, or in mice chronically exposed to PQ. PQ decreased Ub protein content, but not its mRNA transcription. Protein synthesis inhibition with cycloheximide depleted Ub levels and potentiated PQ–induced cell death. Inhibition of proteasomal activity by PQ was found to be a late event in cell death progression, and had no effect on either the toxicity of MPP+ or PQ, or the accumulation of oxidized sulfenylated, sulfonylated (DJ-1/PARK7 and peroxiredoxins) and carbonylated proteins induced by PQ. PQ- and MPP+-induced Ub protein depletion prompted the dimerization/inactivation of the Ub-binding protein p62 that regulates the clearance of ubiquitinated proteins by autophagic. We confirmed that PQ and MPP+ impaired autophagy flux, and that the blockage of autophagy by the overexpression of a dominant-negative form of the autophagy protein 5 (dnAtg5) stimulated their toxicity, but there was no additional effect upon inhibition of the proteasome. PQ induced an increase in the accumulation of α-synuclein in dopaminergic cells and membrane associated foci in yeast cells. Our results demonstrate that inhibition of protein ubiquitination by PQ and MPP+ is involved in the dysfunction of Ub-dependent protein degradation pathways

In memory detection of Windows API call hooking technique

API call hooking is a technique that malware researchers use to mine malware's API calls. These API calls is used to represent malware's behavior, for use in malware analysis, classification or detection of samples. In this paper, analysis of current Windows API call hooking techniques is presented where surprisingly, it was found that detection of each technique can be done trivially in memory. This could lead to malware being able to sense the presence of API call hooking techniques and modifying their behavior during runtime. Suggestions for a better API call hooking technique are presented towards the end of the paper

Investigation on Dyeing Performance of Basic and Reactive Dyes Concerning Jute Fiber Dyeing

This paper includes the investigation on the dyeing performance of reactive and basic dyestuff regarding jute fiber and discusses their benefits and shortcomings. Plain woven jute fabric samples of 261 GSM were dyed with 0.5%, 1.0%, and 4.0% shade of basic and reactive dyes. Then the dyeing performance of both dyestuffs was analyzed. It has been found that exhaustion of basic dye is considerably greater than reactive dye, while this exhaustion decreases for basic dye and increases for reactive dye with the increment of respective shade percentages. This phenomenon has also been verified through the absorption curve, i.e. K/S value of fabric dyed with both dyestuffs in three different shade percentages. Again strong covalent bond is formed during the fixation of reactive dye with the cellulose of jute fiber, and at the same time no strong bond was created in case of basic dye. Finally the color fastness properties have been assessed through rubbing and washing. Both the dye classes have shown nearly similar ratings in case of dry rubbing. However, in case of wet rubbing and wash fastness to color change and color staining; the samples dyed with reactive dyes showed superior fastness ratings over the basic dyed samples