314 research outputs found

    Detection of human papillomavirus DNA in intraosseus ameloblastoma

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    Human Papillomavirus (HPV) infection has been shown as a risk factor in oral carcinogenesis. The association between HPV and benign and malignant neoplasm of oral mucosa, especially surface epithelium-derived tumors, is well established. The role of HPV in pathogenesis of odontogenic cysts and tumors has been published in few articles. The aim of this study was detection of HPV in Iranian patients with intrabony ameloblastoma and investigation of specific risk factors associated with ameloblastoma. One hundred intrabony ameloblastoma and 50 age-sex matched samples as controls were evaluated by polymerase chain reaction for the detection and typing of HPV. Fisher exact and chi square tests were used to assess the data. HPV DNA was detected in 32% of patients and 10% of controls. HPV-6 was the most prevalent genotype (31.6%) in infected cases. It was followed by HPV-11 (12.5%), HPV-16 (12.5%) and HPV-31 (3.1%). We found a significant association between presence of HPV and location of tumor (p = 0.02), traumatic history (p = 0.03) and ododontic therapy (p = 0.01). These findings indicated that HPV-6 probably is one of the most important etiologic agents in causing intraosseous ameloblastoma in Iranian population. © 2006 Academic Journals Inc., USA

    Comparing the Effects of Sulfasalazine and Shilajit on Liver Damage Caused by Acetic Acid-Induced Ulcerative Colitis in Male Rats

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    Background and Objective: Liver damage is one of the common complications after ulcerative colitis. The aim of this study is to compare liver protective effects of sulfasalazine and shilajit after ulcerative colitis. Methods: In this experimental intervention study, 49 male Wistar rats weighing 200-250 grams were used in seven groups of 7: sham, ulcerative colitis, oral solution, oral Shilajit, sulfasalazine, rectal solution, and rectal Shilajit. To induce ulcerative colitis, after anesthetizing the animal, 2 cc of acetic acid (4%) was used by rectal administration. Four days after the development of colitis, Shilajit was administered for four days at a dose of 250 mg/kg by gavage and rectal methods. In each group, the levels of liver enzymes (SGPT, SGOT, ALP), direct bilirubin, total, and serum albumin were evaluated eight days after the induction of ulcerative colitis. Findings: Sulfasalazine decreased total bilirubin (0.5967±0.04) and SGOT (113.3±12.7). Administering Shilajit rectally reduced direct bilirubin (0.10±0.02), albumin (3.17±0.2), SGOT (156.2±12.7) and administering Shilajit by gavage reduced SGOT (125.0±12.7), direct bilirubin (0.094±0.02), SGOT (125.0±12.7) and SGPT (93.8±7.5). Conclusion: The results of the study showed that oral administration of Shilajit has more protective effects on liver damage caused by ulcerative colitis than rectal Shilajit, and this result is comparable to sulfasalazine

    The quality of life in boys with Duchenne muscular dystrophy

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    We conducted a study to evaluate the quality of life in boys with Duchenne muscular dystrophy aged 8–18 years, compared with that in matched healthy controls. A total of 85 boys with Duchenne muscular dystrophy aged 8–18 years and 136 age, sex and living place matched healthy controls were included in this study. Patients and one of their parents separately completed the 27-item Persian version of KIDSCREEN questionnaire (child and adolescent version and parent version). From the children's perspective, the quality of life in patients was found to be lower in two subclasses: “physical activities and health” (p < 0.001) and “friends” (p = 0.005). Parental estimation of their sick child's quality of life was significantly lower than children's own assessment in two subclasses: “physical activities and health” (p < 0.001) and “general mood and feelings” (p < 0.001). Our results indicate that boys with Duchenne muscular dystrophy have quite a satisfactory quality of life. A happier and more hopeful life can be promoted through increasing social support and improving the parental knowledge regarding their child's more positive life perspective. © 2016 Elsevier B.V

    Sequential sampling plan of Metopolophium dirhodum (Hemiptera: Aphididae) in wheat fields

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    Sequential sampling plans of rose-grain aphid, Metopolophium dirhodum (Walker) were developed in wheat fields of Jalilabad region of Varamin, Iran. The aphid population was weekly sampled during 2000-2001. Each sample included 50 wheat stems, which were chosen randomly and the number of aphids was counted. This data was used to describe spatial distribution pattern of M. dirhodum by Taylorâs power law (TPL) and Iwaoâs patchiness regression methods. The results indicated aggregated dispersion pattern of rose-grain aphid population in wheat fields, based on both methods. The TPL provided a better description of the aphidâs spatial distribution. Estimates of two mentioned models led to development of sequential sampling plans, using Green and Kuno methods at precision levels of D = 0.20 and D = 0.30 in terms of confidence interval, respectively. In both sequential sampling plans, the higher sample size obtained as population density decreased and it decreased when precision level increased from 0.30 to 0.20. The required sample size for the estimation of mean aphid density was approximately identical at 0.8 and 8 aphids per tiller in both Greenâs and Kunoâs plans. Greenâs plan was more efficient than Kunoâs model for both lower (⤠0.8 per tiller) and higher (⥠8 per tiller) aphid densities due to its small sample size required and less time needed for sampling. Kunoâs model required fewer samples at the intermediate density range (0.8-8 aphids per tiller) and is considered more effective than Greenâs plan at this aphids' density range. However, Kunoâs model is not recommended when low aphid population density exists because it requires enormous samples of aphids

    The Serum Changes of Neuron-Specific Enolase and Intercellular Adhesion Molecule-1 in Patients With Diffuse Axonal Injury Following Progesterone Administration: A Randomized Clinical Trial

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    Background: Improvement of neurologic outcome in progesterone-administered patients with diffuse axonal injury (DAI) has been found in a recent study. Also, there has been interest in the importance of serum parameters as predictors of outcome in traumatic brain injury. Objectives: The aim of this study was to examine the effect of progesterone administration on serum levels of neuron-specific enolase (NSE), and intercellular adhesion molecule-1 (ICAM-1) in clinical DAI. Patients and Methods: In this study, the serum levels of ICAM-1 and NSE of 32 male DAI patients (18 - 60 years of age, a Glasgow coma scale of 12 or less, and admitted within 4 hours after injury) who were randomized for a controlled phase II trial of progesterone were analyzed. The analysis was performed between the control and progesterone groups at admission time, and 24 hours and six days after DAI, respectively. Results: A reduction in the serum level of ICAM-1 was noticed in the progesterone group 24 hours after the injury (P < 0.05). There was no significant difference in the serum level of NSE between the study groups during evaluation. At 24 hours after the injury, the level of ICAM-1 in the control group was higher than that at admission time (P < 0.05). The lowest level of NSE in the two groups was seen six days after DAI (P < 0.01). Conclusions: In summary, progesterone administration reduced serum ICAM-1, and whereby may attenuate blood brain barrier disruption, the latter needs further investigation for confirmation

    On the Number of Iterations for Dantzig-Wolfe Optimization and Packing-Covering Approximation Algorithms

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    We give a lower bound on the iteration complexity of a natural class of Lagrangean-relaxation algorithms for approximately solving packing/covering linear programs. We show that, given an input with mm random 0/1-constraints on nn variables, with high probability, any such algorithm requires Ω(ρlog(m)/ϵ2)\Omega(\rho \log(m)/\epsilon^2) iterations to compute a (1+ϵ)(1+\epsilon)-approximate solution, where ρ\rho is the width of the input. The bound is tight for a range of the parameters (m,n,ρ,ϵ)(m,n,\rho,\epsilon). The algorithms in the class include Dantzig-Wolfe decomposition, Benders' decomposition, Lagrangean relaxation as developed by Held and Karp [1971] for lower-bounding TSP, and many others (e.g. by Plotkin, Shmoys, and Tardos [1988] and Grigoriadis and Khachiyan [1996]). To prove the bound, we use a discrepancy argument to show an analogous lower bound on the support size of (1+ϵ)(1+\epsilon)-approximate mixed strategies for random two-player zero-sum 0/1-matrix games

    Numerical Investigation of Velocity Profile in Hydraulic Jump Stilling Basin with VOF

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    Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv
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