209 research outputs found

    The cardiac torsion as a sensitive index of heart pathology: A model study.

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    The torsional behaviour of the heart (i.e. the mutual rotation of the cardiac base and apex) was proved to be sensitive to alterations of some cardiovascular parameters, i.e. preload, afterload and contractility. Moreover, pathologies which affect the fibers architecture and cardiac geometry were proved to alter the cardiac torsion pattern. For these reasons, cardiac torsion represents a sensitive index of ventricular performance. The aim of this work is to provide further insight into physiological and pathological alterations of the cardiac torsion by means of computational analyses, combining a structural model of the two ventricles with simple lumped parameter models of both the systemic and the pulmonary circulations. Starting from diagnostic images, a 3D anatomy based geometry of the two ventricles was reconstructed. The myocytes orientation in the ventricles was assigned according to literature data and the myocardium was modelled as an anisotropic hyperelastic material. Both the active and the passive phases of the cardiac cycle were modelled, and different clinical conditions were simulated. The results in terms of alterations of the cardiac torsion in the presence of pathologies are in agreement with experimental literature data. The use of a computational approach allowed the investigation of the stresses and strains in the ventricular wall as well as of the global hemodynamic parameters in the presence of the considered pathologies. Furthermore, the model outcomes highlight how for specific pathological conditions, an altered torsional pattern of the ventricles can be present, encouraging the use of the ventricular torsion in the clinical practice.This is the author accepted manuscript. The final version is available from Elsevier via http://dx.doi.org/10.1016/j.jmbbm.2015.10.00

    Safe Endoscopic Removal of a Migrated Esophageal Stent Using a Protection Hood

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    Abstract Delayed esophageal metallic stent migration after a neo-adjuvant therapy of advanced esophageal cancer is a relatively frequent event, which is sometimes due to tumor response to chemotherapy. Stent migration in the stomach is usually asymptomatic but it can cause potentially life-threatening complications as bowel obstruction or perforation. Most gastric migrations can be managed endoscopically; however endoscopic stent removal could also be a risky procedure due to hemorrhage or esophageal perforation. This case report describes a safe and quick endoscopic method to remove a migrated esophageal metallic stent from the stomach using a protection hood mounted on the tip of the endoscope

    Influence of stochastic estimation on the control of subsonic cavity flow – A preliminary study

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    This work aims at understanding how the different elements involved in the feedback loop influence the overall control performance of a subsonic cavity flow based on reducedorder modeling. To this aim we compare preliminary and limited sets of experimental results obtained by modifying some relevant characteristics of the loop. Our results support the findings in the literature that use of quadratic stochastic estimation is preferable to the linear one for real-time update of the model parameters. They also seem to indicate the merit of using more than one time sample of the pressure for performing the real-time update of the model through stochastic estimation. The effect of using two different sets of pressure signals for the stochastic estimation also corroborates previous findings indicating the need for optimizing the number and the placement of the sensors used in the feedback control loop. Finally we observed that the characteristics of the actuator can alter significantly the overall control effect by introducing in the feedback loop additional, undesirable frequency components that are not modeled and hence controlled. A compensator for the actuator is currently being designed that will alleviate this problem thus enabling a clearer understanding of the overall control technique

    Further development of feedback control of cavity flow using experimental based reduced order model

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    In our recent work we presented preliminary results for subsonic cavity flow control using a reduced-order model based feedback control derived from experimental measurements. The model was developed using the Proper Orthogonal Decomposition of PIV images in conjunction with the Galerkin projection of the Navier-Stokes equations onto the resulting spatial eigenfunctions. A linear-quadratic optimal controller was designed to reduce cavity flow resonance by controlling the time coefficient and tested in the experiments. The stochastic estimation method was used for real-time estimation of the corresponding time coefficients from 4 dynamic surface pressure measurements. The results obtained showed that the controller was capable of reducing the cavity flow resonance at the design Mach 0.3 flow, as well as at other flows with slightly different Mach number. In the present work we present several improvements made to the method. The reduced order model was derived from a larger set of PIV measurements and we used 6 sensors for the stochastic estimation of the instantaneous time coefficients. The reduced order model so obtained shows a better convergence of the time coefficients. This combined with the 6-sensor estimation improves the control performance while using a scaling factor closer to the theoretically expected value. The controller also performed better in off design flow conditions

    Assessing the feasibility of augmenting fall detection systems by relying on UWB-based position tracking and a home robot

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    Falls in the home environment are a primary cause of injury in older adults. According to the U.S. Centers for Disease Control and Prevention, every year, one in four adults 65 years of age and older reports experiencing a fall. A variety of different technologies have been proposed to detect fall events. However, the need to detect all fall instances (i.e., to avoid false negatives) has led to the development of systems marked by high sensitivity and hence a significant number of false alarms. The occurrence of false alarms causes frequent and unnecessary calls to emergency response centers, which are critical resources that should be utilized only when necessary. Besides, false alarms decrease the level of confidence of end-users in the fall detection system with a negative impact on their compliance with using the system (e.g., wearing the sensor enabling the detection of fall events). Herein, we present a novel approach aimed to augment traditional fall detection systems that rely on wearable sensors and fall detection algorithms. The proposed approach utilizes a UWB-based tracking system and a home robot. When the fall detection system generates an alarm, the alarm is relayed to a base station that utilizes a UWB-based tracking system to identify where the older adult and the robot are so as to enable navigating the environment using the robot and reaching the older adult to check if he/she experienced a fall. This approach prevents unnecessary calls to emergency response centers while enabling a tele-presence using the robot when appropriate. In this paper, we report the results of a novel fall detection algorithm, the characteristics of the alarm notification system, and the accuracy of the UWB-based tracking system that we implemented. The fall detection algorithm displayed a sensitivity of 99.0% and a specificity of 97.8%. The alarm notification system relayed all simulated alarm notification instances with a maximum delay of 106 ms. The UWB-based tracking system was found to be suitable to locate radio tags both in line-of-sight and in no-line-of-sight conditions. This result was obtained by using a machine learning-based algorithm that we developed to detect and compensate for the multipath effect in no-line-of-sight conditions. When using this algorithm, the error affecting the estimated position of the radio tags was smaller than 0.2 m, which is satisfactory for the application at hand

    Feedback control design for subsonic cavity flows

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    A benchmark problem in active aerodynamic flow control, suppression of strong pressure oscillations induced by flow over a shallow cavity, is addressed in this paper. Proper orthogonal decomposition and Galerkin projection techniques are used to obtain a reduced-order model of the flow dynamics from experimental data. The model is made amenable to control design by means of a control separation technique, which makes the control input appear explicitly in the equations. A prediction model based on quadratic stochastic estimation correlates flow field data with surface pressure measurements, so that the latter can be used to reconstruct the state of the model in real time. The focus of this paper is on the controller design and implementation. A linear-quadratic optimal controller is designed on the basis of the reduced-order model to suppress the cavity flow resonance. To account for the limitation on the magnitude of the control signal imposed by the actuator, the control action is modified by a scaling factor, which plays the role of a bifurcation parameter for the closed-loop system. Experimental results, in qualitative agreement with the theoretical analysis, show that the controller achieves a significant attenuation of the resonant tone with a redistribution of the energy into other frequencies, and exhibits a certain degree of robustness when operating in off-design conditions

    Experimental results and bifurcation analysis on scaled feedback control for subsonic cavity flows

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    In this paper, we present the latest results of our ongoing research activities in the development of reduced-order models based feedback control of subsonic cavity flows. The model was developed using the Proper Orthogonal Decomposition of Particle Image Velocimetry images in conjunction with the Galerkin projection of the Navier-Stokes equations onto the resulting spatial eigenfunctions. Stochastic Estimation method was used to obtain the state estimation of the Galerkin system from real time surface pressure measurements. A linear-quadratic optimal controller was designed to reduce cavity flow resonance and tested in the experiments. Real-time implementation shows a significant reduction of the sound pressure level within the cavity, with a remarkable attenuation of the resonant tone and a redistribution of the energy into various modes with lower energy levels. A mathematical analysis of the performance of the LQ control, in agreement with the experimental results, is presented and discussed

    Feedback control design for subsonic cavity flows

    Get PDF
    A benchmark problem in active aerodynamic flow control, suppression of strong pressure oscillations induced by flow over a shallow cavity, is addressed in this paper. Proper orthogonal decomposition and Galerkin projection techniques are used to obtain a reduced-order model of the flow dynamics from experimental data. The model is made amenable to control design by means of a control separation technique, which makes the control input appear explicitly in the equations. A prediction model based on quadratic stochastic estimation correlates flow field data with surface pressure measurements, so that the latter can be used to reconstruct the state of the model in real time. The focus of this paper is on the controller design and implementation. A linear-quadratic optimal controller is designed on the basis of the reduced-order model to suppress the cavity flow resonance. To account for the limitation on the magnitude of the control signal imposed by the actuator, the control action is modified by a scaling factor, which plays the role of a bifurcation parameter for the closed-loop system. Experimental results, in qualitative agreement with the theoretical analysis, show that the controller achieves a significant attenuation of the resonant tone with a redistribution of the energy into other frequencies, and exhibits a certain degree of robustness when operating in off-design conditions

    Modeling and feedback control for subsonic cavity flows: A Collaborative approach

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    Feedback control of aerodynamic flows is attracting the attention of researchers from a wide spectrum of specialties, because of its interdisciplinary nature and the challenges inherent to the problem. One of the main goals of the Collaborative Center of Control Science at The Ohio State University is to bring together researchers from different disciplines to advance the science and technology of flow control. This paper presents a comprehensive summary of the effort of the Center on modeling and feedback control of subsonic cavity-flow resonance. In particular, we give a detailed description of the experimental apparatus, including the wind tunnel testbed, the data measurement and acquisition system, and the real time control system. Reduced-order models of the flow dynamics based on physically-oriented linear models and Proper Orthogonal Decomposition are introduced and their effectiveness for control system design discussed. Finally, results obtained with experimental and model-based controller design are discussed. © 2005 IEEE
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