Carcinome métaplasique du sein avec différenciation osseuse extensive: À propos d’un cas

Le carcinome métaplasique du sein est une entité rare et bien individualisé par l'OMS. Il représente moins de 1 % des cancers invasifs du sein et constitue un groupe tumoral hétérogène soit purement épithélial soit à doublecontingent épithélial et mésenchymateuse. Le carcinome métaplasique avec différenciation osseuse extensive est très rare. Il représente 0.2% des carcinomes du sein. Nous rapportant un cas exceptionnel d'un carcinome métaplasique du sein avec différenciation osseuse extensive chez une patiente de 53 ans. A travers ce cas et une revue de la littérature, les caractéristiques anatomo-cliniques, radiologique, thérapeutiques et évolutives seront discutées

Confounders in the assessment of the renal effects associated with low-level urinary cadmium: an analysis in industrial workers

<p>Abstract</p> <p>Background</p> <p>Associations of proteinuria with low-level urinary cadmium (Cd) are currently interpreted as the sign of renal dysfunction induced by Cd. Few studies have considered the possibility that these associations might be non causal and arise from confounding by factors influencing the renal excretion of Cd and proteins.</p> <p>Methods</p> <p>We examined 184 healthy male workers (mean age, 39.5 years) from a zinc smelter (n = 132) or a blanket factory (n = 52). We measured the concentrations of Cd in blood (B-Cd) and the urinary excretion of Cd (U-Cd), retinol-binding protein (RBP), protein HC and albumin. Associations between biomarkers of metal exposure and urinary proteins were assessed by simple and multiple regression analyses.</p> <p>Results</p> <p>The medians (interquartile range) of B-Cd (μg/l) and U-Cd (μg/g creatinine) were 0.80 (0.45-1.16) and 0.70 (0.40-1.3) in smelter workers and 0.66 (0.47-0.87) and 0.55 (0.40-0.90) in blanket factory workers, respectively. Occupation had no influence on these values, which varied mainly with smoking habits. In univariate analysis, concentrations of RBP and protein HC in urine were significantly correlated with both U-Cd and B-Cd but these associations were substantially weakened by the adjustment for current smoking and the residual influence of diuresis after correction for urinary creatinine. Albumin in urine did not correlate with B-Cd but was consistently associated with U-Cd through a relationship, which was unaffected by smoking or diuresis. Further analyses showed that RBP and albumin in urine mutually distort their associations with U-Cd and that the relationship between RBP and Cd in urine was almost the replicate of that linking RBP to albumin</p> <p>Conclusions</p> <p>Associations between proteinuria and low-level urinary Cd should be interpreted with caution as they appear to be largely driven by diuresis, current smoking and probably also the co-excretion of Cd with plasma proteins.</p

Application of chemometric analysis to infrared spectroscopy for the identification of wood origin

Chemical characteristics of wood are used in this study for plant taxonomy classification based on the current Angiosperm Phylogeny Group classification (APG III System) for the division, class and subclass of woody plants. Infrared spectra contain information about the molecular structure and intermolecular interactions among the components in wood but the understanding of this information requires multivariate techniques for the analysis of highly dense datasets. This article is written with the purposes of specifying the chemical differences among taxonomic groups, and predicting the taxa of unknown samples with a mathematical model. Principal component analysis, t-test, stepwise discriminant analysis and linear discriminant analysis, were some of the chosen multivariate techniques. A procedure to determine the division, class, subclass and order of unknown samples was built with promising implications for future applications of Fourier Transform Infrared spectroscopy in wood taxonomy classification

Prior Tonsillectomy and the Risk of Breast Cancer in Females: A Systematic Review and Meta-analysis

BackgroundExposure to recurrent infections in childhood was linked to an increased risk of cancer in adulthood. There is also evidence that a history of tonsillectomy, a procedure often performed in children with recurrent infections, is linked to an increased risk of leukemia and Hodgkin lymphoma. Tonsillectomy could be directly associated with cancer risk, or it could be a proxy for another risk factor such as recurrent infections and chronic inflammation. Nevertheless, the role of recurrent childhood infections and tonsillectomy on the one hand, and the risk of breast cancer (BC) in adulthood remain understudied. Our study aims to verify whether a history of tonsillectomy increases the risk of BC in women.MethodsA systematic review was performed using PubMed, Google Scholar, Scopus, Embase, and Web of Science databases from inception to January 25, 2022, to identify the studies which assessed the association between the history of tonsillectomy and BC in females. Odds ratio (OR) was calculated using the random/fixed-effects models to synthesize the associations between tonsillectomy and BC risk based on heterogeneity.ResultsEight studies included 2252 patients with breast cancer of which 1151 underwent tonsillectomy and 5314 controls of which 1725 had their tonsils removed. Patients with a history of tonsillectomy showed a higher subsequent risk of developing BC (OR, 1.24; 95% CI: 1.11-1.39) as compared to patients without a history of tonsillectomy. Influence analyses showed that no single study had a significant effect on the overall estimate or the heterogeneity.ConclusionsOur study revealed that a history of tonsillectomy is associated with an increased risk of breast cancer. These findings underscore the need for frequent follow-ups and screening of tonsillectomy patients to assess for the risk of BC

Tabellen zur Aktivierung und Abschirmung der dabei entstandenen Radionuklide

Bei Reaktorexperimenten stellt die Aktivierung der verwendeten Werkstoffe eine unangenehme ßegleiterscheinung dar, deren Ausmaßbei der Auswahl der Materialien so weit wie möglich berücksichtigt werden muß. Eine Vorausberechnung der auftretenden Aktivitäten sowie der notwendigen Abschirmung ist unerläßlich. Es schien uns deshalb angebracht, eine Zusammenstellung der Daten der häufig in Legierungen (auch als Spur) vorkommenden Elemente zu schaffen, die es uns und auch anderen Interessenten erlaubt, ohne unnötig großen Zeitaufwand solche Serechnungen durchzuführen. Die Tabellen umfassen Aktivierungsdaten, die der im Verzeichnis aufgeführten Literatur entnommen sind sov1ie Abschirmungsdaten nach Rockwell und ANL 5800. Sie erlaubt je nach Problemstellung,die spezifischen Aktivitäten (Ci/g), die Dosisleistung (mrem/h) der unabgeschirmten Quellen sowie die Abschirmdicken zu ermitteln.Die Einführuno zu der Benutzung dieser Tabellen gibt eine übersieht der Begriffe, die im Zusammenhang mit Aktivierungs- undAbschirmberechnungen stehen. Die Einführung ist in vier Abschnitte unterteilt. Die drei ersten Abschnitte besprechen nacheinander die Ermittlung der Aktivität, der Dosisleistung und der notwendigen Abschirmung. Jeder Abschnitt schließt mit einer kurzen Zusammenfassung und einem einfachen Beispiel. Die Beispiele bilden eine Fortsetzung und zeigen, wie man anhand der beigefügten Tabellen von der Aktivität ausgehend die notwendige Abschirmung bestimmt. Der vierte Abschnitt behandelt kurz die Aktivierungvon Kühlkreisläufen. Ausgehend von der so ermittelten Aktivität des Kreislaufes, kann die Dosisleistung und die dazu notwendige Abschirmung bestimmt werden, so wie es in den vorherigen Abschnitten (1, 2 und 3) gezeigt worden ist. Deshalb wird hier auf ein Beispiel verzichtet. Bezeichnungen und häufig benutzte Einheiten sind deutlichkeitshalber am Anfang der Einführung zusammengefaßt

Relaxed energetic maps of -carrabiose: A DFT study

Posterno abstrac

Multipole rate coefficients for collisional excitation of Fe XIII by isotropic electrons

The multipole rate coefficients $$C^K$$ for excitation of highly charged ions by impact with isotropic electrons are required in the analysis of intensity and polarization of line emission from hot plasmas exposed to anisotropic external radiation. Assuming a Maxwellian electron energy distribution, we calculate $$C^K$$ for transitions between fine-structure levels of the Si-like ion Fe XIII in the temperature range $$(0.7-5)\times 10^6$$ K. Selected results for transitions within the $$3s^23p^2$$ ground configuration and from $$3s^23p^2$$ to $$3s^23p3d$$ levels are given. These transitions are of interest in solar corona diagnostics based on the infrared forbidden lines at 1074.7 and 1079.8 nm and extreme ultraviolet optically-allowed lines at 202.0 and 203.8 Å. To obtain $$C^K$$, we need the multipole collision strengths $$\varOmega ^K$$ which we calculate in a wide range of electron energy in the relativistic distorted-wave approximation, using a modified version of the excitation program of the Flexible Atomic Code

Structural and thermal study of mesomorphic dodecylammonium carrageenates

Structural characteristics and thermal stability of a series of dodecylammonium carrageenates formed by stoichiometric complexation of dodecylammonium chloride and differently charged carrageenans (kappa-, iota- and lambda-carrageenan, respectively) were investigated. IR spectral analysis confirmed the electrostatic and hydrogen bond interactions between the dodecylammonium and carrageenan species. X-ray diffraction experiments show increased ordering in the complexes compared to that in the parent carrageenans. Dodecylammonium carrageenates have a layer structure, in which a polar sublayer contains layers of carrageenan chains and a nonpolar sublayer consists of conformationally disordered dodecylammonium chains electrostatically attached to the carrageenan backbone. The major factor that determines the dodecylammonium carrageenate structure is cationic surfactant, while the carrageenans moiety plays a major role in determining thermal properties. (C) 2009 Elsevier Inc. All rights reserved