Detection of incorrect and inappropriateImagefrom Tweets in Social Network

Digital imaging has grown to become the prevalent technology for creating, processing, and storing digital memory and proof. Though this technology brings many leverage, it can be used as a ambiguous tool for covering details and evidences. This is because today digital images can be tampered in such supremacy that forgery cannot be find visually. In fact, the immunity concern of digital content has arisen a long time ago and different methods to verify the efficiency of digital images have been developed. Digital images offer many features for forgery detection algorithm to take precedence of specifically the color and brightness of individual pixels as well as an image�s resolution and format. These properties grant for analysis and similarity between the significance of digital forgeries in an attempt to develop an algorithm for detecting image tampering. This paper presents a technique for image copy or move image forgery detection using Radix Sort, FasterK-means clustering algorithm & DCT

New transit observations for HAT-P-30 b, HAT-P-37 b, TrES-5 b, WASP-28 b, WASP-36 b, and WASP-39 b

We present new transit light curves for planets in six extrasolar planetary systems. They were acquired with 0.4-2.2 m telescopes located in west Asia, Europe, and South America. When combined with literature data, they allowed us to redetermine system parameters in a homogeneous way. Our results for individual systems are in agreement with values reported in previous studies. We refined transit ephemerides and reduced uncertainties of orbital periods by a factor between 2 and 7. No sign of any variations in transit times was detected for the planets studied.Comment: Submitted to Acta Astronomic

Transit Timing Analysis in the HAT-P-32 system

We present the results of 45 transit observations obtained for the transiting exoplanet HAT-P-32b. The transits have been observed using several telescopes mainly throughout the YETI network. In 25 cases, complete transit light curves with a timing precision better than $1.4\:$min have been obtained. These light curves have been used to refine the system properties, namely inclination $i$, planet-to-star radius ratio $R_\textrm{p}/R_\textrm{s}$, and the ratio between the semimajor axis and the stellar radius $a/R_\textrm{s}$. First analyses by Hartman et al. (2011) suggest the existence of a second planet in the system, thus we tried to find an additional body using the transit timing variation (TTV) technique. Taking also literature data points into account, we can explain all mid-transit times by refining the linear ephemeris by 21ms. Thus we can exclude TTV amplitudes of more than $\sim1.5$min.Comment: MNRAS accepted; 13 pages, 10 figure

Transit Timing Analysis in the HAT-P-32 System

We present the results of 45 transit observations obtained for the transiting exoplanet HATP- 32b. The transits have been observed using several telescopes mainly throughout the YETI (Young Exoplanet Transit Initiative) network. In 25 cases, complete transit light curves with a timing precision better than 1.4 min have been obtained. These light curves have been used to refine the system properties, namely inclination i, planet-to-star radius ratio Rp/Rs, and the ratio between the semimajor axis and the stellar radius a/Rs. First analyses by Hartman et al. suggests the existence of a second planet in the system, thus we tried to find an additional body using the transit timing variation (TTV) technique. Taking also the literature data points into account, we can explain all mid-transit times by refining the linear ephemeris by 21 ms. Thus, we can exclude TTV amplitudes of more than ∼1.5min

Comparison between ultrasound guided and landmark – based technique for superficial cervical plexus block in patients undergoing thyroid surgery

Background: The major advantage of ultrasound guided technique over the traditional landmark technique in bilateral superficial cervical plexus block is that, it helps to minimize the injury to cervical muscle, fascia and nerves. The study aimed to compare the effectiveness between landmark technique and ultrasound guided technique with respect to the post-operative analgesia, intra-operative hemodynamics and the complication rate of the procedure. Methodology: A total of 100 patients were included as our study sample which was divided into two groups of 50 each. Group A patients received Superficial Cervical Plexus Block (SCPB) using the landmark based technique and Group B patients received SCPB under ultrasound guided technique. Parameters such as success of the procedure performance time, time of onset of action, block pain score, post-operative pain score, intra-operative hemodynamics and complication rate were compared between the two groups. Results: The success rate of the block was found to be 72% in the landmark technique group compared to 90% in the ultrasound guided group. The onsite time of analgesia was found to be much earlier in ultrasound guided group (16.2 vs 11.1 mins). The hemodynamic parameters were found to be slightly higher among the landmark group compared to ultrasound guided group. Post-operative pain score was significantly better and the incidence of complication rate was nil among ultrasound guided group. Conclusion: Ultrasound guided technique is a better alternate for landmark technique for providing bilateral superficial cervical plexus block while performing thyroidectomy surgery

Clinical variants of the native class d beta-lactamase of acinetobacter baumannii pose an emerging threat through ıncreased hydrolytic activity against carbapenems

The threat posed by the chromosomally encoded class D beta-lactamase of Acinetobacter baumannii (OXA-51/66) has been unclear, in part because of its relatively low affinity and turnover rate for carbapenems. Several hundred clinical variants of OXA51/66 have been reported, many with substitutions of active-site residues. We determined the kinetic properties of OXA-66 and five clinical variants with respect to a wide variety of beta-lactam substrates. The five variants displayed enhanced activity against carbapenems and in some cases against penicillins, late-generation cephalosporins, and the monobactam aztreonam. Molecular dynamics simulations show that in OXA-66, P130 inhibits the side-chain rotation of I129 and thereby prevents doripenem binding because of steric clash. A single amino acid substitution at this position (P130Q) in the variant OXA-109 greatly enhances the mobility of both I129 and a key active-site tryptophan (W222), thereby facilitating carbapenem binding. This expansion of substrate specificity represents a very worrisome development for the efficacy of beta-lactams against this troublesome pathogen.HHS \ NIH \ National Institute of Allergy and Infectious Diseases (NIAID):1R15AI082416 National Science Foundation (NSF): CNS-122829

Constraints on a second planet in the WASP-3 system

There have been previous hints that the transiting planet WASP-3 b is accompanied by a second planet in a nearby orbit, based on small deviations from strict periodicity of the observed transits. Here we present 17 precise radial velocity measurements and 32 transit light curves that were acquired between 2009 and 2011. These data were used to refine the parameters of the host star and transiting planet. This has resulted in reduced uncertainties for the radii and masses of the star and planet. The radial-velocity data and the transit times show no evidence for an additional planet in the system. Therefore, we have determined the upper limit on the mass of any hypothetical second planet, as a function of its orbital period.Comment: Accepted for publication in The Astronomical Journa

Comparison of verona integron-borne metallo-beta-lactamase (VIM) variants reveals differences in stability and inhibition profiles

DUZGUN, AZER OZAD/0000-0002-6301-611X; Abboud, Martine I./0000-0003-2141-5988; Brem, Jurgen/0000-0002-0137-3226; McDonough, Michael A/0000-0003-4664-6942; Rydzik, Anna/0000-0003-3158-0493; DUZGUN, AZER OZAD/0000-0002-6301-611X; McDonough, Michael/0000-0003-4664-6942; Schofield, Christopher/0000-0002-0290-6565; SANDALLI, Cemal/0000-0002-1298-3687WOS: 000376490800025PubMed: 26666919Metallo-beta-lactamases (MBLs) are of increasing clinical significance; the development of clinically useful MBL inhibitors is challenged by the rapid evolution of variant MBLs. the Verona integron-borne metallo-beta-lactamase (VIM) enzymes are among the most widely distributed MBLs, with > 40 VIM variants having been reported. We report on the crystallographic analysis of VIM-5 and comparison of biochemical and biophysical properties of VIM-1, VIM-2, VIM-4, VIM-5, and VIM-38. Recombinant VIM variants were produced and purified, and their secondary structure and thermal stabilities were investigated by circular dichroism analyses. Steady-state kinetic analyses with a representative panel of beta-lactam substrates were carried out to compare the catalytic efficiencies of the VIM variants. Furthermore, a set of metalloenzyme inhibitors were screened to compare their effects on the different VIM variants. the results reveal only small variations in the kinetic parameters of the VIM variants but substantial differences in their thermal stabilities and inhibition profiles. Overall, these results support the proposal that protein stability may be a factor in MBL evolution and highlight the importance of screening MBL variants during inhibitor development programs.Rhodes Trust; Scientific and Technology Council of Turkey; Recep Tayyip Erdogan Universitesi Research FundRecep Tayyip Erdogan University [BAP-2013.102.03.13]; Medical Research CouncilMedical Research Council UK (MRC) [MR/L007665/1]; Medical Research Council/Canadian Grant [G1100135]; Biochemical Society Krebs Memorial Award; Medical Research CouncilMedical Research Council UK (MRC) [G1100135, MR/N002679/1] Funding Source: researchfishThe Rhodes Trust provided funding to Anne Makena. Scientific and Technology Council of Turkey provided funding to Cemal Sandalli. Recep Tayyip Erdogan Universitesi Research Fund provided funding to Aysegul Saral, Aysegul C. Cicek, and Cemal Sandalli under grant number BAP-2013.102.03.13. Medical Research Council provided funding to Jurgen Brem, Michael A. McDonough, Anna M. Rydzik, and Christopher J. Schofield under grant number MR/L007665/1. Medical Research Council/Canadian Grant provided funding to Jurgen Brem, Michael A. McDonough, Anna M. Rydzik, and Christopher J. Schofield under grant number G1100135. Biochemical Society Krebs Memorial Award provided funding to Martine I. Abboud

New Transit Observations for HAT-P-30 b, HAT-P-37 b, TrES-5 b, WASP-28 b, WASP-36 b and WASP-39 b

We present new transit light curves for planets in six extrasolar planetary systems. They were acquired with 0.4–2.2 m telescopes located in west Asia, Europe, and South America. When combined with literature data, they allowed us to redetermine system parameters in a homogeneous way. Our results for individual systems are in agreement with values reported in previous studies. We refined transit ephemerides and reduced uncertainties of orbital periods by a factor between 2 and 7. No sign of any variations in transit times was detected for the planets studied.Fil: Maciejewski, G.. Nicolaus Copernicus University; PoloniaFil: Dimitrov, D.. Bulgarian Academy Of Sciences; BulgariaFil: Mancini, L.. Max Planck Institute for Astronomy; Alemania. Osservatorio Astrofisico Di Torino; Italia. Istituto Nazionale di Astrofisica; ItaliaFil: Southworth, J.. Keele University; Reino UnidoFil: Ciceri, S.. Max Planck Institute For Astronomy; AlemaniaFil: D'Ago, G.. Istituto Internazionale per gli Alti Studi ; ItaliaFil: Bruni, I.. Osservatorio Astrofisico di Bologna; Italia. Istituto Nazionale di Astrofisica; ItaliaFil: Raetz, St.. Universitat Erlangen-nurmberg. Astronomisches Institut-dr. Karl Remeis-sternwarte & Ecap; Alemania. European Space Agency; Países BajosFil: Nowak, G.. Instituto de Astrofísica de Canarias; España. Nicolaus Copernicus University; Polonia. Universidad de La Laguna; EspañaFil: Ohlert, J.. University of Applied Sciences; Alemania. Michael Adrian Observatorium; AlemaniaFil: Puchalski, D.. Nicolaus Copernicus University; PoloniaFil: Saral, G.. Istanbul University; Turquía. University Of Geneva (ug);Fil: Derman, E.. Ankara University; TurquíaFil: Petrucci, Romina Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Jofré, E.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; ArgentinaFil: Seeliger, M.. Universitat Erlangen-nurmberg. Astronomisches Institut-dr. Karl Remeis-sternwarte & Ecap; AlemaniaFil: Henning, T.. Max Planck Institute for Astronomy; Alemani