Higgs Couplings in Composite Models

We study Higgs couplings in the composite Higgs model based on the coset SO(5)/SO(4). We show that the couplings to gluons and photons are insensitive to the elementary-composite mixings and thus not affected by light fermionic resonances. Moreover, at leading order in the mixings the Higgs couplings to tops and gluons, when normalized to the Standard Model (SM), are equal. These properties are shown to be direct consequences of the Goldstone symmetry and of the assumption of partial compositeness. In particular, they are independent of the details of the elementary-composite couplings and, under the further assumption of CP invariance, they are also insensitive to derivative interactions of the Higgs with the composite resonances. We support our conclusions with an explicit construction where the SM fermions are embedded in the 14 dimensional representation of SO(5).Comment: 13 pages, 3 figures, 2 tables; v2: small improvements in the discussion, results unchanged; typos corrected; one reference added. Matches version submitted to PR

RELATIONSHIP OF DOCOSAHEXAENOIC ACID SUPPLEMENTATION AND INSULINE RESISTANCE IN OBESE CHILDREN

BACKGROUND: obesity may be associated with a later onset of chronic disorders and clinical complications. Insulin resistance, glucose intolerance and hyperinsulinemia are major components of the metabolic syndrome, which is highly prevalent among children and adolescents with severe obesity. Low levels of LCPUFAs, especially docosahexaenoic acid (C22:6 n-3, [DHA]) and a high n-6/n-3 LCPUFA ratio in skeletal muscle membrane phospholipids have been associated with insulin resistance in adults. Recent data suggest that the synthesis of DHA differs between obese children and normal weight children. In particular, in obese children, the highest quartile of BMI z-score was associated with higher plasma levels of the n-6/n-3 LCPUFA ratio. Given the high prevalence of insulin resistance in childhood obesity, we asked whether supplementation with DHA would be more effective than diet and physical activity alone in reducing this metabolic alteration. AIM: to determine whether DHA supplementation, in addition to adequate diet and lifestyle, may reduce insulin resistance compared with diet and physical activity only, in obese children. Secondary aims were to evaluate whether may exist an association of the change of steatosis degree after the intervention with DHA supplementation... SUBJECTS AND METHODS: this is a multicenter, longitudinal, double-blind, randomized, placebo-controlled trial that started on January 01, 2010. Up to September 30, 2012, thirty (14 boys, 16 girls, mean [SD] age, 11.4 [1.29] years, range 8-13), were recruited. All obese children consecutively admitted to the Department of Paediatrics, San Paolo Hospital, Milan, and to the Department of Paediatrics, Federico II Hospital, Naples, for routine examinations were assessed for eligibility. The study protocol scheduled daily oral supplementation of either an intervention \u201cproduct\u201d, that is two capsule of purified DHA (500 mg) or two capsule of wheat germ oil (500 mg). A nutritional-behavioural intervention was additionally recommended in all recruited children promoting a normocaloric balanced diet and an active lifestyle based on the Italian guidelines for treatment of childhood obesity. Additional recommendations were given to engage in a moderate daily exercise program (30-45 minutes/day aerobic physical exercise), tailored to individual preferences. Children were visited at the care centers within 3\ub11 days (baseline) after enrolment, and at 6 months after starting intervention. Evaluations included anthropometrical measurements, nutritional, metabolic assessment and liver ultrasonography. Children were randomly assigned to the intervention or control group based on a computer generated, blocked randomization list by each center. A block size of four was used, stratified according to gender. The investigator who generated the randomization sequence was independent of the research staff and unaware of children. RESULTS: at baseline there was no significant difference between groups for any anthropometrical (minimum P= 0.806) or dietary (minimum P= 0.318) or biochemical (minimum P=0.539) variable. No significant difference among groups occurred for daily intake of energy or any macronutrient and the end of the study (minimum P=0.111). At the end of the intervention a significant reduction of plasma fasting glucose (DHA group P=0.046; placebo group P=0.048), insulin (DHA group P=0.001; placebo group P=0.048) and HOMA (DHA group P=0.001; placebo group P=0.050) in both groups was observed. A higher percentage variation of plasma fasting insulin (P=0.0046) and HOMA (P=0.0045) in DHA than placebo group was showed. There was a difference between groups for percentage reduction of liver steatosis: in DHA group from 14 to 7 % (P=0.655), in placebo group from 20 to 13 % (P=0.275)

Early (and Later) LHC Search Strategies for Broad Dimuon Resonances

Resonance searches generally focus on narrow states that would produce a sharp peak rising over background. Early LHC running will, however, be sensitive primarily to broad resonances. In this paper we demonstrate that statistical methods should suffice to find broad resonances and distinguish them from both background and contact interactions over a large range of previously unexplored parameter space. We furthermore introduce an angular measure we call ellipticity, which measures how forward (or backward) the muon is in eta, and allows for discrimination between models with different parity violation early in the LHC running. We contrast this with existing angular observables and demonstrate that ellipticity is superior for discrimination based on parity violation, while others are better at spin determination.Comment: 31 pages, 19 figures. References added, minor modifications made to section

Non-universal minimal Z' models: present bounds and early LHC reach

We consider non-universal 'minimal' Z' models, whose additional U(1) charge is a non-anomalous linear combination of the weak hypercharge Y, the baryon number B and the partial lepton numbers (L_e, L_mu, L_tau), with no exotic fermions beyond three standard families with right-handed neutrinos. We show that the observed pattern of neutrino masses and mixing can be fully reproduced by a gauge-invariant renormalizable Lagrangian, and flavor-changing neutral currents in the charged lepton sector are suppressed by a GIM mechanism. We then discuss the phenomenology of some benchmark models. The electrophilic B-3L_e model is significantly constrained by electroweak precision tests, but still allows to fit the hint of an excess observed by CDF in dielectrons but not in dimuons. The muonphilic B-3L_mu model is very mildly constrained by electroweak precision tests, so that even the very early phase of the LHC can explore significant areas of parameter space. We also discuss the hadrophobic L_mu-L_tau model, which has recently attracted interest in connection with some puzzling features of cosmic ray spectra.Comment: 29 pages, 13 figure

Minimal Z' models: present bounds and early LHC reach

We consider `minimal' Z' models, whose phenomenology is controlled by only three parameters beyond the Standard Model ones: the Z' mass and two effective coupling constants. They encompass many popular models motivated by grand unification, as well as many arising in other theoretical contexts. This parameterization takes also into account both mass and kinetic mixing effects, which we show to be sizable in some cases. After discussing the interplay between the bounds from electroweak precision tests and recent direct searches at the Tevatron, we extend our analysis to estimate the early LHC discovery potential. We consider a center-of-mass energy from 7 towards 10 TeV and an integrated luminosity from 50 to several hundred pb^-1, taking all existing bounds into account. We find that the LHC will start exploring virgin land in parameter space for M_Z' around 700 GeV, with lower masses still excluded by the Tevatron and higher masses still excluded by electroweak precision tests. Increasing the energy up to 10 TeV, the LHC will start probing a wider range of Z' masses and couplings, although several hundred pb^-1 will be needed to explore the regions of couplings favored by grand unification and to overcome the Tevatron bounds in the mass region around 250 GeV.Comment: 25 pages. v2: small improvements and minor corrections, version accepted for publication on JHE

Effects of β2-receptor stimulation by indacaterol in chronic heart failure treated with selective or non-selective β-blockers: a randomized trial

Alveolar \u3b22-receptor blockade worsens lung diffusion in heart failure (HF). This effect could be mitigated by stimulating alveolar \u3b22-receptors. We investigated the safety and the effects of indacaterol on lung diffusion, lung mechanics, sleep respiratory behavior, cardiac rhythm, welfare, and exercise performance in HF patients treated with a selective (bisoprolol) or a non-selective (carvedilol) \u3b2-blocker. Study procedures were performed before and after indacaterol and placebo treatments according to a cross-over, randomized, double-blind protocol in forty-four patients (27 on bisoprolol and 17 on carvedilol). No differences between indacaterol and placebo were observed in the whole population except for a significantly higher VE/VCO2 slope and lower maximal PETCO2 during exercise with indacaterol, entirely due to the difference in the bisoprolol group (VE/VCO2 31.8\u2009\ub1\u20095.9 vs. 28.5\u2009\ub1\u20095.6, p\u2009<\u20090.0001 and maximal PETCO2 36.7\u2009\ub1\u20095.5 vs. 37.7\u2009\ub1\u20095.8\u2009mmHg, p\u2009<\u20090.02 with indacaterol and placebo, respectively). In carvedilol, indacaterol was associated with a higher peak heart rate (119\u2009\ub1\u200934 vs. 113\u2009\ub1\u200930 bpm, with indacaterol and placebo) and a lower prevalence of hypopnea during sleep (3.8 [0.0;6.3] vs. 5.8 [2.9;10.5] events/hour, with indacaterol and placebo). Inhaled indacaterol is well tolerated in HF patients, it does not influence lung diffusion, and, in bisoprolol, it increases ventilation response to exercise

Product Differentiation Costs and Global Competition

The growing competitive intensity on the markets determines the emergence of competition costs that are expressed at a corporate level and have implicit repercussions for the supply system. This type of costs makes it possible to identify a close link between competition costs and supply differentiation costs. Classification by competitive intensity presupposes that the analysis performed identifies the classification of company costs as the discriminating element, in terms of the competitive pressure of the context in which the firm operates. The emergence of competition costs is linked to an attempt to squeeze them as an aspect of vertical, or more specifically, horizontal cooperation strategies.Product Differentiation; Differentiation Costs; Over-Supply; Global Competition; Marketing; Market-Driven Management; Global Corporations; Global Markets DOI:http://dx.doi.org/10.4468/2005.1.06garbelli

Higgs Mass from D-Terms: a Litmus Test

We explore supersymmetric theories in which the Higgs mass is boosted by the non-decoupling D-terms of an extended $U(1)_X$ gauge symmetry, defined here to be a general linear combination of hypercharge, baryon number, and lepton number. Crucially, the gauge coupling, $g_X$, is bounded from below to accommodate the Higgs mass, while the quarks and leptons are required by gauge invariance to carry non-zero charge under $U(1)_X$. This induces an irreducible rate, $\sigma$BR, for $pp \rightarrow X \rightarrow \ell\ell$ relevant to existing and future resonance searches, and gives rise to higher dimension operators that are stringently constrained by precision electroweak measurements. Combined, these bounds define a maximally allowed region in the space of observables, ($\sigma$BR, $m_X$), outside of which is excluded by naturalness and experimental limits. If natural supersymmetry utilizes non-decoupling D-terms, then the associated $X$ boson can only be observed within this window, providing a model independent `litmus test' for this broad class of scenarios at the LHC. Comparing limits, we find that current LHC results only exclude regions in parameter space which were already disfavored by precision electroweak data.Comment: 7 pages, 9 figure

Low Scale Flavor Gauge Symmetries

We study the possibility of gauging the Standard Model flavor group. Anomaly cancellation leads to the addition of fermions whose mass is inversely proportional to the known fermion masses. In this case all flavor violating effects turn out to be controlled roughly by the Standard Model Yukawa, suppressing transitions for the light generations. Due to the inverted hierarchy the scale of new gauge flavor bosons could be as low as the electroweak scale without violating any existing bound but accessible at the Tevatron and the LHC. The mechanism of flavor protection potentially provides an alternative to Minimal Flavor Violation, with flavor violating effects suppressed by hierarchy of scales rather than couplings.Comment: 24 pages + appendices; v2) Refs. added and numerical examples improved. Results unchanged; v3) small typos in appendix B correcte