975 research outputs found
A Mixed-Methods Investigation of First-Year Learning Communities in a Private, Midwestern University
In the 2017-2018 academic year, the School of Humanities of a private, Midwestern university began a pilot program of two first-year learning communities in the Fall, with an additional learning community in the Spring. Each learning community consisted of three theme-linked courses, for a total of nine courses over two semesters. As the study unfolded, the first and the third of the learning communities lived up to expectations of the faculty and administrators as communities of increased engagement and academic success. The second community struggled with engagement and both students and faculty felt that their theme-linked group failed to demonstrate the desired effects of learning communities. Research on learning communities has been heavily quantitative, based primarily on National Survey of Student Engagement (NSSE) data (Arensdorf & Naylor-Tincknell, 2016; Malnarich et al., 2014). Therefore, the lack of qualitative data on learning communities formed a research gap, and I planned this research project to be primarily qualitative. Research focused on interviews and focus groups of both the student and faculty. The purpose of this study was to investigate how students and faculty experienced their participation in a learning community pilot project, or why students and faculty would engage in learning communities. With profound differences between the two first-semester communities, the question also arose as to why one community would flourish, while the other struggled. What makes a learning community successful for student and faculty participants
Impact of schizophrenia on anterior and posterior hippocampus during memory for complex scenes.
ObjectivesHippocampal dysfunction has been proposed as a mechanism for memory deficits in schizophrenia. Available evidence suggests that the anterior and posterior hippocampus could be differentially affected. Accordingly, we used fMRI to test the hypothesis that activity in posterior hippocampus is disproportionately reduced in schizophrenia, particularly during spatial memory retrieval.Methods26 healthy participants and 24 patients with schizophrenia from the UC Davis Early Psychosis Program were studied while fMRI was acquired on a 3 Tesla Siemens scanner. During encoding, participants were oriented to critical items through questions about item features (e.g., "Does the lamp have a square shade?") or spatial location (e.g., "Is the lamp on the table next to the couch?"). At test, participants determined whether scenes were changed or unchanged. fMRI analyses contrasted activation in a priori regions of interest (ROI) in anterior and posterior hippocampus during correct recognition of item changes and spatial changes.ResultsAs predicted, patients with schizophrenia exhibited reduced activation in the posterior hippocampus during detection of spatial changes but not during detection of item changes. Unexpectedly, patients exhibited increased activation of anterior hippocampus during detection of item changes. Whole brain analyses revealed reduced fronto-parietal and striatal activation in patients for spatial but not for item change trials.ConclusionsResults suggest a gradient of hippocampal dysfunction in which posterior hippocampus - which is necessary for processing fine-grained spatial relationships - is underactive, and anterior hippocampus - which may process context more globally - is overactive
Stellar and Molecular Radii of a Mira Star: First Observations with the Keck Interferometer Grism
Using a new grism at the Keck Interferometer, we obtained spectrally
dispersed (R ~ 230) interferometric measurements of the Mira star R Vir. These
data show that the measured radius of the emission varies substantially from
2.0-2.4 microns. Simple models can reproduce these wavelength-dependent
variations using extended molecular layers, which absorb stellar radiation and
re-emit it at longer wavelengths. Because we observe spectral regions with and
without substantial molecular opacity, we determine the stellar photospheric
radius, uncontaminated by molecular emission. We infer that most of the
molecular opacity arises at approximately twice the radius of the stellar
photosphere.Comment: 12 pages, including 3 figures. Accepted by ApJ
Functional network changes and cognitive control in schizophrenia
Cognitive control is a cognitive and neural mechanism that contributes to managing the complex demands of day-to-day life. Studies have suggested that functional impairments in cognitive control associated brain circuitry contribute to a broad range of higher cognitive deficits in schizophrenia. To examine this issue, we assessed functional connectivity networks in healthy adults and individuals with schizophrenia performing tasks from two distinct cognitive domains that varied in demands for cognitive control, the RiSE episodic memory task and DPX goal maintenance task. We characterized general and cognitive control-specific effects of schizophrenia on functional connectivity within an expanded frontal parietal network (FPN) and quantified network topology properties using graph analysis. Using the network based statistic (NBS), we observed greater network functional connectivity in cognitive control demanding conditions during both tasks in both groups in the FPN, and demonstrated cognitive control FPN specificity against a task independent auditory network. NBS analyses also revealed widespread connectivity deficits in schizophrenia patients across all tasks. Furthermore, quantitative changes in network topology associated with diagnostic status and task demand were observed. The present findings, in an analysis that was limited to correct trials only, ensuring that subjects are on task, provide critical insights into network connections crucial for cognitive control and the manner in which brain networks reorganize to support such control. Impairments in this mechanism are present in schizophrenia and these results highlight how cognitive control deficits contribute to the pathophysiology of this illness
First Keck Nulling Observations of a Young Stellar Object: Probing the Circumstellar Environment of the Herbig Ae star MWC 325
We present the first N-band nulling plus K- and L-band V2 observations of a
young stellar object, MWC325, taken with the 85 m baseline Keck Interferometer.
The Keck nuller was designed for the study of faint dust signatures associated
with debris disks, but it also has a unique capability for studying the
temperature and density distribution of denser disks found around young stellar
objects. Interferometric observations of MWC 325 at K, L and N encompass a
factor of five in spectral range and thus, especially when spectrally dispersed
within each band, enable characterization of the structure of the inner disk
regions where planets form. Fitting our observations with geometric models such
as a uniform disk or a Gaussian disk show that the apparent size increases
monotonically with wavelength in the 2-12 um wavelength region, confirming the
widely held assumption based on radiative transfer models, now with spatially
resolved measurements over broad wavelength range, that disks are extended with
a temperature gradient. The effective size is a factor of about 1.3 and 2
larger in the L-band and N-band, respectively, compared to that in the K-band.
The existing interferometric measurements and the spectral energy distribution
can be reproduced by a flat disk or a weakly-shadowed nearly flat-disk model,
with only slight flaring in the outer regions of the disk, consisting of
representative "sub-micron" (0.1 um) and "micron" (2 um) grains of a 50:50
ratio of silicate and graphite. This is marked contrast with the disks
previously found in other Herbig Ae/Be stars suggesting a wide variety in the
disk properties among Herbig Ae/Be stars.Comment: Accepted for publication in the Ap
AFS Server Logging
The AFS servers at the Center for Information Technology Integration have been modified to trace and log file server activity. This report discusses the AFS modifications and the structure of the trace files and data. We also describe three large datasets collected from the logging servers, available to other researchers.http://deepblue.lib.umich.edu/bitstream/2027.42/107953/1/citi-tr-93-10.pd
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Differential medial temporal lobe morphometric predictors of item- and relational-encoded memories in healthy individuals and in individuals with mild cognitive impairment and Alzheimer's disease.
INTRODUCTION:Episodic memory processes are supported by different subregions of the medial temporal lobe (MTL). In contrast to a unitary model of memory recognition supported solely by the hippocampus, a current model suggests that item encoding engages perirhinal cortex, whereas relational encoding engages parahippocampal cortex and the hippocampus. However, this model has not been examined in the context of aging, neurodegeneration, and MTL morphometrics. METHODS:Forty-four healthy subjects (HSs) and 18 cognitively impaired subjects (nine mild cognitive impairment [MCI] and nine Alzheimer's disease [AD] patients) were assessed with the relational and item-specific encoding task (RISE) and underwent 3T magnetic resonance imaging. The RISE assessed the differential contribution of relational and item-specific memory. FreeSurfer was used to obtain measures of cortical thickness of MTL regions and hippocampus volume. RESULTS:Memory accuracies for both item and relational memory were significantly better in the HS group than in the MCI/AD group. In MCI/AD group, relational memory was disproportionately impaired. In HSs, hierarchical regressions demonstrated that memory was predicted by perirhinal thickness after item encoding, and by hippocampus volume after relational encoding (both at trend level) and significantly by parahippocampal thickness at associative recognition. The same brain morphometry profiles predicted memory accuracy in MCI/AD, although more robustly perirhinal thickness for item encoding (R2 = 0.31) and hippocampal volume and parahippocampal thickness for relational encoding (R2 = 0.31). DISCUSSION:Our results supported a model of episodic memory in which item-specific encoding was associated with greater perirhinal cortical thickness, while relational encoding was associated with parahippocampal thickness and hippocampus volume. We identified these relationships not only in HSs but also in individuals with MCI and AD. In the subjects with cognitive impairment, reductions in hippocampal volume and impairments in relational memory were especially prominent
Keck Interferometer nuller instrument performance
The Keck Interferometer combines the two 10 m Keck telescopes as a long baseline interferometer. It is funded by NASA as a joint development among the Jet Propulsion Laboratory, the W. M. Keck Observatory, and the NASA Exoplanet Science Institute. In February 2008, the 10 um nulling mode began a 32 night observing program with three key science teams to perform a survey of nearby stars for exozodiacal dust. This program has recently concluded, and has been followed by nuller observing on a variety of science topics through the standard proposal process. We provide a review and update of the nuller implementation, and describe the data reduction process, including the calibration approach. We then review the technical performance of the instrument based on the full key science data set, including sensitivity and systematic errors. We also provide some summary data on atmospheric effects applicable to the cophasing approach
First L-band Interferometric Observations of a Young Stellar Object: Probing the Circumstellar Environment of MWC 419
We present spatially-resolved K- and L-band spectra (at spectral resolution R
= 230 and R = 60, respectively) of MWC 419, a Herbig Ae/Be star. The data were
obtained simultaneously with a new configuration of the 85-m baseline Keck
Interferometer. Our observations are sensitive to the radial distribution of
temperature in the inner region of the disk of MWC 419. We fit the visibility
data with both simple geometric and more physical disk models. The geometric
models (uniform disk and Gaussian) show that the apparent size increases
linearly with wavelength in the 2-4 microns wavelength region, suggesting that
the disk is extended with a temperature gradient. A model having a power-law
temperature gradient with radius simultaneously fits our interferometric
measurements and the spectral energy distribution data from the literature. The
slope of the power-law is close to that expected from an optically thick disk.
Our spectrally dispersed interferometric measurements include the Br gamma
emission line. The measured disk size at and around Br gamma suggests that
emitting hydrogen gas is located inside (or within the inner regions) of the
dust disk.Comment: Accepted for publication in Ap
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