Occult laryngeal foreign body mimicking normal thyroid cartilage

Introduction: Foreign body aspiration is common especially in children. The absence of history of choking does not rule out the diagnosis. Diagnosis required high index of suspicion. Case Presentation: Undiagnosed foreign body aspiration mostly occurs in bronchial airway rather than larynx and can cause severe complications. In this article, we report a silent laryngeal foreign body aspiration to show that careful history taking and accurate evaluation of radiography are important factors for diagnosis. Conclusions: The single most significant factor leading to detect of tracheobronchial foreign body aspiration is a high index of suspicion; this case highlights the possibility of a foreign body in the airway in patients who presents with a recent onset of chronic respiratory complaints. © 2015, Trauma Monthly

A histological study on the development of the digestive tract of Caspian salmon, Salmo trutta caspius (Kessleri), from hatching to parr stage

Histological development of digestive tract of the Caspian salmon, Salmo trutta caspius, from hatching to 6 month post-hatching was studied using light microscope. The digestive tract of newly hatched larvae was a simple, undifferentiated tube which continued from mouth to anus. In 10 days post hatching larvae, the alimentary canal became more differentiated and secretion was started activity, with appearance of goblet cells in epithelium of the mouth, pharynx and esophagus. A thin layer of neutral mucopolysaccharid components covered the digestive tract's epithelium in this stage. At the onset of exogenous feeding (25 days post hatch, dph, at 70C), the digestive tract became completely differentiated into mouth, pharynx, esophagus, glandular and non-glandular stomach, primary pyloric cacea, anterior and posterior parts of the intestine and rectum, similar to those of juveniles and adults. The alimentary canal was structurally completed and lined by a stratified squamous epithelium in the mouth, pharynx and rudimentry part of the esophagus at 25 dph, while the terminal part of esophagus, the stomach and the intestine were lined by a columnar epithelium. During this period, striated muscle layer became distinct from mouth to esophagus, while smooth muscle layer was appeared at the stomach and intestine. This pattern did not change up to six month post hatch, except in development of the digestive organs. Histological analysis of the present study prepare some basic scientific knowledge on the Caspian salmon's digestive histology which may be used in further studies on digestive system, such as histochemical studies

A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon

<p>Abstract</p> <p>Background</p> <p>We report an extremely rare case of concomitant huge exophytic GIST of the stomach and Kasabach-Merritt phenomenon (KMP).</p> <p>Case presentation</p> <p>The patient was a 67-year-old man experiencing abdominal distension since September 2006. A physical examination revealed a 25 × 30 cm hard mass that was palpable in the middle and lower left abdomen minimal intrinsic mobility and massive ascites. Since the admitted patient was diagnosed with DIC, surgery could not be performed. The patient received a platelet transfusion and the DIC was treated. Due to this treatment, the platelet count recovered to 7.0 × 10⁴; tumor resection was performed at 16 days after admission. Laparotomy revealed a huge extraluminal tumor arising from the greater curvature of the stomach that measured 25 × 30 cm and had not ruptured into the peritoneal cavity or infiltrated other organs. Partial gastric resection was performed. The resected mass measured 25 × 25 × 20 cm. In cross section, the tumor appeared hard and homogenous with a small polycystic area. Histopathology of the resected specimen showed large spindle cell GIST with >5/50 HPF (high-power field) mitotic activity. The postoperative course was uneventful, and the coagulopathy improved rapidly.</p> <p>Conclusion</p> <p>Since the characteristic of tumor in this case was hypervascularity with bleeding and necrotic lesions, coagulopathy was thought to be caused by the trapping of platelets within a large vasculized tumor mass.</p

Theoretically nanoscale study on ionization of muscimol nano drug in aqueous solution

In the present work, acid dissociation constant (pKa) values of muscimol derivatives were calculated using the Density Functional Theory (DFT) method. In this regard, free energy values of neutral, protonated and deprotonated species of muscimol were calculated in water at the B3LYP/6-31G(d) basis sets. The hydrogen bond formation of all species had been analyzed using the Tomasi's method. It was revealed that the theoretically calculated pKa values were in a good agreement with the existing experimental pKa values, which were determined from capillary electrophoresis, potentiometric titration and UV-visible spectrophotometric measurements

Knowledge management through mobile networks in emergency situations

This paper concerns public emergency situations, which are the responsibility of a select set of organisations in the public, private and community sectors. It reports on an analysis of the knowledge management implications of mobile networks, using wireless technology designed for such situations. This follows the path of a research project concerning the need to integrate technological, logistical and organisational knowledge management issues within and between organisations with regard to their response to emergency situations. The analysis of a secondary case is used to illustrate and analyse the issue using a realistic and holistic approach

Management of nasofrontal angle in rhinoplasty

Radix or nasofrontal angle has a special concern in rhinoplasty. Minimal changes in the position of nasofrontal angle can produce a different image of nasal and midfacial length in the profile view. In a patient with high radix, the profile of the forehead continues into the nose in a straight line and the nose appears too long. On the other hand, deep nasofrontal angle makes the illusion of a short nose. The ideal position of this angle has always been a matter of discussion and various methods have been introduced regarding its correction by deepening or augmenting the radix area. In this article, we first review the ideal position of nasofrontal angle and then discuss different procedures used to correct it. ©Iranian Red Crescent Medical Journal

Gorlin's syndrome presenting as recurrent mandibular cyst infection

A 38 year-old man with a history of painful swelling in the left mandibular angle region and skin lesions on the upper chest is reported. The symptoms, findings, diagnostic criteria and the approach for treatment are reviewed. Histological examinations of mandibular cystic and skin nodular lesions were reported as "Inflamed Keratinous Cyst" and "Basal Cell Carcinoma". It is important to consider the syndrome encountering multiple jaw cysts because of the high recurrence rate, associated medical problems, and need for close life-long follow-up of this syndrome. ©Iranian Red Crescent Society

Impact of endoscopic endonasal pituitary surgery on nasal airway patency

Background: Nose is used as a corridor in endoscopic endonasal transsphenoidal approach (EETSA) for pituitary adenoma. Thus, it may affect the nasal airway patency, function and sinonasal-related quality of life. The aim of this study is to objectively and subjectively evaluate these effects. Methods: In this prospective study, 43 patients with pituitary adenoma who were candidates for EETSA from March 2012 to October 2013 were enrolled. The patients were evaluated preoperatively using acoustic rhinometry and rhinomanometry (with/without the use of decongestant drops) and asked to complete the 22-Item Sinonasal Outcome Test (SNOT-22) questionnaire. The tests were repeated at one and three months postoperatively. The preoperative data were compared with the first and second postoperative ones using paired-sample t-test. Results: Without the use of decongestant drops, the total airway resistance increased significantly (p = 0.016), and the nasal airflow decreased significantly (p = 0.031) in the first postoperative evaluation. However, in the 3rd postoperative month, the difference was not significant. With the use of decongestant drops, the objective parameters showed no significant changes compared to preoperative data even at the first evaluation. The SNOT- 22 scores also did not differ significantly in 1st and 3rd postoperative months. The first postoperative SNOT-22 showed a strong correlation with the second minimal cross-sectional area on simultaneous evaluation, and with the preoperative total airway resistance. Conclusion: EETSA has a transient adverse effect on the nasal patency that quickly improves, making it a safe approach for the sinonasal system. Rhinomanometry is the most sensitive test for detecting these nasal functional changes objectively