966 research outputs found

    Magnetohydrodynamic generators using two-phase liquid-metal flows

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    Two-phase flow generator cycle of a magnetohydrodynamic /MHD/ generator uses a working fluid which is compressible and treated as an expanding gas. The two-phase mixture passes from the heat source through the MHD generator, where the expansion process takes place and the electrical energy is extracted

    Studies of cycles for liquid-metal magnetohydrodynamic generation of power

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    Studies of liquid-metal magnetohydrodynamic power cycles indicate that the overall efficiency of a binary cycle, employing a liquid-metal topping cycle and a bottoming steam cycle, may reach 60 percent. Details of analyses and data on cycles are presented, and the commercial potential of the binary cycle is discussed

    Separation of <sup>3</sup>He and CH<sub>4</sub> signals on the Mid-Atlantic Ridge at 5°N and 51°N

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    Abiogenic methane may be produced in submarine hydrothermal systems by degassing of basalts or serpentinization of ultramafic outcrops. The latter process presumably releases little primordial helium and is therefore implicated by high CH4/3He ratios in vent fluids from the ultramafic-hosted Rainbow field and in methane plumes near ultramafic outcrops. We report the existence of depth-separated CH4 and 3He plumes in two segments of the Mid-Atlantic Ridge, at 5.4°N and 51°N. In both cases, the helium plume was deeper, near the valley floor, and the methane carbon isotope ratio was heavy (d13C ˜ -14%). The plumes may issue from separate vents, where the helium is discharged near the volcanic axis and the methane is generated by serpentinization higher on the valley wall. However, at the present time the locations of the vents that produce these plumes are not known. Using a one-pass model, we investigated whether separate venting could arise from heat conduction from a primary, helium-carrying, hydrothermal circulation to a second, shallower fracture loop intersecting ultramafic rock. The model results indicate that the flow rate through the secondary loop would have to be relatively low in order for it to stay warm enough for serpentinization to proceed. In this case, some of the exothermic heat production is lost by conduction, and the temperature increase in the circulating fluid is only a fraction of that expected from a water/rock ratio of 1:1

    Untargeted lipidomic features associated with colorectal cancer in a prospective cohort.

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    BackgroundEpidemiologists are beginning to employ metabolomics and lipidomics with archived blood from incident cases and controls to discover causes of cancer. Although several such studies have focused on colorectal cancer (CRC), they all followed targeted or semi-targeted designs that limited their ability to find discriminating molecules and pathways related to the causes of CRC.MethodsUsing an untargeted design, we measured lipophilic metabolites in prediagnostic serum from 66 CRC patients and 66 matched controls from the European Prospective Investigation into Cancer and Nutrition (Turin, Italy). Samples were analyzed by liquid chromatography-high-resolution mass spectrometry (LC-MS), resulting in 8690 features for statistical analysis.ResultsRather than the usual multiple-hypothesis-testing approach, we based variable selection on an ensemble of regression methods, which found nine features to be associated with case-control status. We then regressed each selected feature on time-to-diagnosis to determine whether the feature was likely to be either a potentially causal biomarker or a reactive product of disease progression (reverse causality).ConclusionsOf the nine selected LC-MS features, four appear to be involved in CRC etiology and merit further investigation in prospective studies of CRC. Four other features appear to be related to progression of the disease (reverse causality), and may represent biomarkers of value for early detection of CRC

    Obstacles to the Revival of Mobile Grazing Systems in Kazakhstan

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    Livestock mobility was an essential characteristic of Kazakh livestock production systems, allowing animals to take advantage of spatial and temporal variability in climate and vegetation, optimising forage intake over the year. These systems broke down following the end of the Soviet Union. In this paper we examine the extent and determinants of the recovery of mobile livestock husbandry in south-eastern Kazakhstan, using surveys and semi-structured interviews with livestock farmers and rural households (holding livestock but not registered as farms). We find positive relationships between livestock holding size and probability of mobility. Winter pastures are particularly important for large farms, with households and smaller farms more dependent on supplementary fodder. The major formal property right over pasture is the long-term leasehold, allocated by auction and associated with significant transaction costs. Leasehold markets function poorly, so farms use a combination of leasing, subleasing and short-term contracts with local authorities to assemble the pastoral resources they need. Few farmers conduct more than a simplified summer-winter migration, whilst around 30% of farms and 70% of households (which own the bulk of livestock) are entirely sedentary, staying on over-used village pastures all year round. Many of these producers express a desire for improved pasture access. The 2017 Law on Pastures introduced district-level pasture use planning, with promotion of mobility and allocation of remote pastures to those with poor access. But the Law does not include new land tenure mechanisms appropriate for small producers (owning few livestock and without leaseholds) which can be employed to realise this goal. Moreover, most pastures are already leased. We discuss options for grazing system management which may simultaneously increase the economic contribution of pastures, improve their condition and reduce rural inequalities created by disparities in access to resources

    Using Pareto Fronts to Evaluate Polyp Detection Algorithms for CT Colonography

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    We evaluate and improve an existing curvature-based region growing algorithm for colonic polyp detection for our CT colonography (CTC) computer-aided detection (CAD) system by using Pareto fronts. The performance of a polyp detection algorithm involves two conflicting objectives, minimizing both false negative (FN) and false positive (FP) detection rates. This problem does not produce a single optimal solution but a set of solutions known as a Pareto front. Any solution in a Pareto front can only outperform other solutions in one of the two competing objectives. Using evolutionary algorithms to find the Pareto fronts for multi-objective optimization problems has been common practice for years. However, they are rarely investigated in any CTC CAD system because the computation cost is inherently expensive. To circumvent this problem, we have developed a parallel program implemented on a Linux cluster environment. A data set of 56 CTC colon surfaces with 87 proven positive detections of polyps sized 4 to 60 mm is used to evaluate an existing one-step, and derive a new two-step region growing algorithm. We use a popular algorithm, the Strength Pareto Evolutionary Algorithm (SPEA2), to find the Pareto fronts. The performance differences are evaluated using a statistical approach. The new algorithm outperforms the old one in 81.6% of the sampled Pareto fronts from 20 simulations. When operated at a suitable sensitivity level such as 90.8% (79/87) or 88.5% (77/87), the FP rate is decreased by 24.4% or 45.8% respectively

    Low-frequency ocean bottom pressure variations in the North Pacific in response to time-variable surface winds

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    One decade of time-variable gravity field observations from the GRACE satellite mission reveals low-frequency ocean bottom pressure (OBP) variability of up to 2.5 hPa centered at the northern flank of the subtropical gyre in the North Pacific. From a 145 year-long simulation with a coupled chemistry climate model, OBP variability is found to be related to the prevailing atmospheric sea-level pressure and surface wind conditions in the larger North Pacific area. The dominating atmospheric pressure patterns obtained from the climate model run allow in combination with ERA-Interim sea-level pressure and surface winds a reconstruction of the OBP variability in the North Pacific from atmospheric model data only, which correlates favorably (r=0.7) with GRACE ocean bottom pressure observations. The regression results indicate that GRACE-based OBP observations are indeed sensitive to changes in the prevailing sea-level pressure and thus surface wind conditions in the North Pacific, thereby opening opportunities to constrain atmospheric models from satellite gravity observations over the oceans
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