The designer of the 90's: A live demonstration

A survey of design tools to be used by the aircraft designer is given. Structural reliability, maintainability, cost and predictability, and acoustics expert systems are discussed, as well as scheduling, drawing, engineering systems, sizing functions, and standard parts and materials data bases

Interfacial interaction of water and silicate minerals

This program has relation to the categories of the nature of water and water cycle. In particular, the study deals with the basic interactions of water with the surface of minerals. The program has direct application to the areas groundwater and water in soils in the category of water cycle. We have investigated the problems of bonding and migration of water molecules upon sheet structures of mineral samples. The minerals used in the program have surface structures that are similar and in some cases identical to those found in clays. This study focused upon the molecular level rather than on the bulk property level of capillarity and hydraulics. The interlayer binding energy of selenite was measured. The measurements were made within a test chamber in which the temperature and atmospheric pressure of the sample could be controlled and monitored. There was found to be no significant difference in the IBE of selenite in air (716 ergs/cm^2) and in vacuum (704 ergs/cm^2). There was found to be a slight difference in the low temperature IBE (768 ergs/cm^2) and the high temperature IBE (720 ergs/cm^2); however, this was attributable to effects of cold on the mechanism. It was concluded that the IBE io independent of atmospheric and temperature effects within the range of temperature and pressure studied.Project # A-057-MO Agreement # 14-31-0001-382

Real STEM: Scientific Research for Rural Georgia Students

This poster will tell the story of creating a STEM research experience for students through a partnership between research institutes, University Faculty and high school teachers. The poster will provide a visual showing how the grant work was structured, barriers to implementation and successes that spur us on to continue to bring STEM experiences to rural, southeast Georgia

Precipitation Extremes in Dynamically Downscaled Climate Scenarios over the Greater Horn of Africa

This study first assesses the performance of regional climate models in the Coordinated Regional Climate Downscaling Experiment (CORDEX) in reproducing observed extreme precipitation indices over the Greater Horn of Africa (GHA) region during 1989–2005. The study then assesses projected changes in these extremes during 2069–2098 compared to 1976–2005. The Regional Climate Model (RCM) simulations are made using two RCMs, with large-scale forcing from four CMIP5 Global limate Models(GCMs) under two Representative Concentration Pathways (RCP4.5 and RCP8.5). We found that RCM simulations have reasonably captured observed patterns of moderate precipitation extreme indices (MPEI). Pattern correlation coefficients between simulated and observed MPEI exceed 0.5 for all except the Simple Daily Intensity Index (SDII). However, significant overestimations or underestimations exist over localized areas in the region. Projected changes in Total annual Precipitation (PRCPTOT) and the annual number of heavy (\u3e10 mm) and very heavy (\u3e20 mm) precipitation days by 2069–2098 show a general north-south pattern, with decreases over the southern half and increases over the northern half of the GHA. These changes are often greatest over parts of Somalia, Eritrea, the Ethiopian highlands and southern Tanzania. Maximum one- and five-day precipitation totals over a year and SDII (ratio of PRCPTOT to rainy days) are projected to increase over a majority of the GHA, including areas where PRCPTOT is projected to decrease, suggesting fewer, but heavier rainy days in the future. Changes in the annual sum of daily precipitation above the 95th and 99th percentiles are statistically significant over a few locations, with the largest projected decrease/increase over Eritrea and northwestern Sudan/Somalia. Projected changes in Consecutive Dry Days (CDD) suggest longer periods of dryness over the majority of the GHA, except the central portions covering northern Uganda, southern South Sudan, southeastern Ethiopia and Somalia. Substantial increases in CDD are located over southern Tanzania and the Ethiopian highlands. The magnitude and the spatial extent of statistically-significant changes in all MPEI increase from RCP4.5 to RCP8.5, and the separation between positive and negative changes becomes clearer under RCP8.5

MicroRNAs in inflammatory lung disease - master regulators or target practice?

MicroRNAs (miRNAs) have emerged as a class of regulatory RNAs with immense significance in numerous biological processes. When aberrantly expressed miRNAs have been shown to play a role in the pathogenesis of several disease states. Extensive research has explored miRNA involvement in the development and fate of immune cells and in both the innate and adaptive immune responses whereby strong evidence links miRNA expression to signalling pathways and receptors with critical roles in the inflammatory response such as NF-κB and the toll-like receptors, respectively. Recent studies have revealed that unique miRNA expression profiles exist in inflammatory lung diseases such as cystic fibrosis, chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis and lung cancer. Evaluation of the global expression of miRNAs provides a unique opportunity to identify important target gene sets regulating susceptibility and response to infection and treatment, and control of inflammation in chronic airway disorders. Over 800 human miRNAs have been discovered to date, however the biological function of the majority remains to be uncovered. Understanding the role that miRNAs play in the modulation of gene expression leading to sustained chronic pulmonary inflammation is important for the development of new therapies which focus on prevention of disease progression rather than symptom relief. Here we discuss the current understanding of miRNA involvement in innate immunity, specifically in LPS/TLR4 signalling and in the progression of the chronic inflammatory lung diseases cystic fibrosis, COPD and asthma. miRNA in lung cancer and IPF are also reviewed

Precipitation Extremes in Dynamically Downscaled Climate Scenarios over the Greater Horn of Africa

This study first assesses the performance of regional climate models in the Coordinated Regional Climate Downscaling Experiment (CORDEX) in reproducing observed extreme precipitation indices over the Greater Horn of Africa (GHA) region during 1989–2005. The study then assesses projected changes in these extremes during 2069–2098 compared to 1976–2005. The Regional Climate Model (RCM) simulations are made using two RCMs, with large-scale forcing from four CMIP5 Global limate Models(GCMs) under two Representative Concentration Pathways (RCP4.5 and RCP8.5). We found that RCM simulations have reasonably captured observed patterns of moderate precipitation extreme indices (MPEI). Pattern correlation coefficients between simulated and observed MPEI exceed 0.5 for all except the Simple Daily Intensity Index (SDII). However, significant overestimations or underestimations exist over localized areas in the region. Projected changes in Total annual Precipitation (PRCPTOT) and the annual number of heavy (\u3e10 mm) and very heavy (\u3e20 mm) precipitation days by 2069–2098 show a general north-south pattern, with decreases over the southern half and increases over the northern half of the GHA. These changes are often greatest over parts of Somalia, Eritrea, the Ethiopian highlands and southern Tanzania. Maximum one- and five-day precipitation totals over a year and SDII (ratio of PRCPTOT to rainy days) are projected to increase over a majority of the GHA, including areas where PRCPTOT is projected to decrease, suggesting fewer, but heavier rainy days in the future. Changes in the annual sum of daily precipitation above the 95th and 99th percentiles are statistically significant over a few locations, with the largest projected decrease/increase over Eritrea and northwestern Sudan/Somalia. Projected changes in Consecutive Dry Days (CDD) suggest longer periods of dryness over the majority of the GHA, except the central portions covering northern Uganda, southern South Sudan, southeastern Ethiopia and Somalia. Substantial increases in CDD are located over southern Tanzania and the Ethiopian highlands. The magnitude and the spatial extent of statistically-significant changes in all MPEI increase from RCP4.5 to RCP8.5, and the separation between positive and negative changes becomes clearer under RCP8.5

Real STEM: Scientific Research for Rural Georgia High School Students

This is the story of creating a STEM research experience for students through a partnership between research institutes, University Faculty and high school teachers. The story of Real STEM will include a discussion of how the grant work is structured, barriers to implementation and successes that spur us on to continue to bring STEM experiences to rural, southeast Georgia

Wireless Chemical Sensing Method

A wireless chemical sensor includes an electrical conductor and a material separated therefrom by an electric insulator. The electrical conductor is an unconnected open-circuit shaped for storage of an electric field and a magnetic field. In the presence of a time-varying magnetic field, the first electrical conductor resonates to generate harmonic electric and magnetic field responses. The material is positioned at a location lying within at least one of the electric and magnetic field responses so-generated. The material changes in electrical conductivity in the presence of a chemical-of-interest

Wireless Chemical Sensor and Sensing Method for Use Therewith

A wireless chemical sensor includes an electrical conductor and a material separated therefrom by an electric insulator. The electrical conductor is an unconnected open-circuit shaped for storage of an electric field and a magnetic field. In the presence of a time-varying magnetic field, the first electrical conductor resonates to generate harmonic electric and magnetic field responses. The material is positioned at a location lying within at least one of the electric and magnetic field responses so-generated. The material changes in electrical conductivity in the presence of a chemical-of-interest

Wireless Chemical Sensor and Sensing Method for Use Therewith

A wireless chemical sensor includes an electrical conductor and a material separated therefrom by an electric insulator. The electrical conductor is an unconnected open-circuit shaped for storage of an electric field and a magnetic field. In the presence of a time-varying magnetic field, the first electrical conductor resonates to generate harmonic electric and magnetic field responses. The material is positioned at a location lying within at least one of the electric and magnetic field responses so-generated. The material changes in electrical conductivity in the presence of a chemical-of-interest