331 research outputs found
Tendiendo puentes entre la academia y las dinámicas educativas
La divulgación del conocimiento producido por los maestroscomo resultado de sus procesos de investigación, constituyeuna valiosa oportunidad para visibilizar la riqueza cognitiva,textual y pedagógica del saber docente.
Consulte el libro visitando el siguiente enlace: https://descubridor.idep.edu.co/Record/ir-001-2571A través del conocimiento compartido se generan redes detransmisión de conocimiento, tendiendo puentes entre el mundoacadémico y las dinámicas escolares.La convocatoria para la publicación de libros basadosen trabajos de posgrado con distinciones académicas,escritos por docentes, constituyó una oportunidad defortalecimiento de la apropiación y divulgación delconocimiento producido por maestros de Bogotá. Elresultado fue la Serie Incentiva digital Maestros y Maestras10, que reunió en 2022 doce publicaciones
Cephalometric And Anthropometric Data Of Obstructive Apnea In Different Age Groups
Introduction: Patients with obstructive sleep apnea syndrome usually present with changes in syndromes; upper airway morphology and/or body fat distribution, which may occur throughout life and Cephalometry; increase the severity of obstructive sleep apnea syndrome with age. Body mass index; Objective: To correlate cephalometric and anthropometric measures with obstructive sleep Anthropometry; apnea syndrome severity in different age groups. Cervical rib; Methods: A retrospective study of cephalometric and anthropometric measures of 102 patients Obesity with obstructive sleep apnea syndrome was analyzed. Patients were divided into three age groups (>= 20 and = 40 and = 60 years). Pearson's correlation was performed for these measures with the apnea-hypopnea index in the full sample, and subsequently by age group. Results: The cephalometric measures MP-H (distance between the. mandibular plane and the hyoid bone) and PNS-P (distance between the posterior nasal spine and the tip of the soft palate) and the neck and waist circumferences showed a statistically significant correlation with apnea-hypopnea index in both the full sample and in the >= 40 and = 60 years). Conclusion: Cephalometric measurements MP-H and PNS-P and cervical and waist circumferences correlated with obstructive sleep apnea syndrome severity in patients in the >= 40 and <60 age group. (C) 2014 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial. Published by Elsevier Editora Ltda. All rights reserved.811798
Comparison Of Standardized Dichloromethane With Aqueous Pterodon Pubescens Benth. Fruit Extracts On Antinociceptive And Anti-inflammatory Activity
Pterodon pubescens Benth., popularly known as "sucupira", is traditionally used as pain healing agent for many inflammatory diseases. The present study evaluated the in vivo antinociceptive and anti-inflammatory properties of sucupira's fruit dicloromethane extract (Pp) compared to the aqueous extract (Ppa) traditionally used in folk medicine. Extracts' chemical characterization was performed by gas chromatography coupled to mass spectra (GC-MS) detection. The standardized extracts were evaluated using antinociceptive and anti-inflammatory experimental models with mice. The results reported herein allowed establishing a relationship between the popular use of Pterodon pubescens fruit for pain relief and the activity of two major compounds isolated from this species which demonstrated antinociceptive activity. The experimental models corroborate activity of aqueous extract antinociceptive and anti-inflammatory activity, with lower potency compared to dichloromethane extract. Nevertheless the resulting data corroborates sucupira's folk use for pain relief.28345546
Comparison Of Standardized Dichloromethane With Aqueous Pterodon Pubescens Benth. Fruit Extracts On Antinociceptive And Anti-inflammatory Activity
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Pterodon pubescens Benth., popularly known as "sucupira", is traditionally used as pain healing agent for many inflammatory diseases. The present study evaluated the in vivo antinociceptive and anti-inflammatory properties of sucupira's fruit dicloromethane extract (Pp) compared to the aqueous extract (Ppa) traditionally used in folk medicine. Extracts' chemical characterization was performed by gas chromatography coupled to mass spectra (GC-MS) detection. The standardized extracts were evaluated using antinociceptive and anti-inflammatory experimental models with mice. The results reported herein allowed establishing a relationship between the popular use of Pterodon pubescens fruit for pain relief and the activity of two major compounds isolated from this species which demonstrated antinociceptive activity. The experimental models corroborate activity of aqueous extract antinociceptive and anti-inflammatory activity, with lower potency compared to dichloromethane extract. Nevertheless the resulting data corroborates sucupira's folk use for pain relief.283455464FCF/UNICAMPFundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)Conselho Nacional para o Desenvolvimento Cientifico e Tecnologico (CNPq)Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES
Chemerin receptor blockade improves vascular function in diabetic obese mice via redox-sensitive- and Akt-dependent pathways
Chemerin and its G protein-coupled receptor [chemerin receptor 23 (ChemR23)] have been associated with endothelial dysfunction, inflammation, and insulin resistance. However, the role of chemerin on insulin signaling in the vasculature is still unknown. We aimed to determine whether chemerin reduces vascular insulin signaling and whether there is interplay between chemerin/ChemR23, insulin resistance, and vascular complications associated with type 2 diabetes (T2D). Molecular and vascular mechanisms were probed in mesenteric arteries and cultured vascular smooth muscle cells (VSMCs) from C57BL/6J, nondiabetic lean db/m, and diabetic obese db/db mice as well as in human microvascular endothelial cells (HMECs). Chemerin decreased insulin-induced vasodilatation in C57BL/6J mice, an effect prevented by CCX832 (ChemR23 antagonist) treatment. In VSMCs, chemerin, via oxidative stress- and ChemR23-dependent mechanisms, decreased insulin-induced Akt phosphorylation, glucose transporter 4 translocation to the membrane, and glucose uptake. In HMECs, chemerin decreased insulin-activated nitric oxide signaling. AMP-activated protein kinase phosphorylation was reduced by chemerin in both HMECs and VSMCs. CCX832 treatment of db/db mice decreased body weight, insulin, and glucose levels as well as vascular oxidative stress. CCX832 also partially restored vascular insulin responses in db/db and high-fat diet-fed mice. Our novel in vivo findings highlight chemerin/ChemR23 as a promising therapeutic target to limit insulin resistance and vascular complications associated with obesity-related diabetes
Competencia en los mercados de telecomunicación tradicionales y OTT
Purpose ”“ Economic activity is based increasingly on the Internet. This development generates multiple benefits for consumers but also competition challenges for operators and regulatory authorities.
Methodology/approach/design ”“ The study considers the recent evolution of the traditional voice, messaging and video telecommunications services, as well as OTT of similar functionality that coexist in the markets with them. Based on the literature review, the degree of substitution and / or complementarity between traditional services and OTT is analyzed from a demand perspective.
Findings ”“ No conclusions can be set, as certain conditions of consumption substitution is observed, while in others, complementarity between services. From the perspective of suppliers, there is a certain complementarity that is reflected in a greater number of associations between operators and OTT.Propósito ”“ Una economía basada cada vez más en el Internet genera múltiples beneficios para los consumidores, pero también retos de competencia para los operadores y regulatorios para las autoridades.
Metodología ”“ El estudio considera la evolución reciente de los tres servicios tradicionales de telecomunicación, voz, mensajería y video, así como los OTT de funcionalidad similar que coexisten con ellos. Con base en la revisión bibliográfica, se analiza desde una perspectiva de la demanda, el grado de sustitución y/o complementariedad entre los servicios tradicionales y OTT.
Resultados ”“ Se encuentra que, a la fecha, no hay conclusiones contundentes, ya que bajo ciertas condiciones de consumo se observa sustitución, mientras en otras, complementariedad entre los servicios. Desde la perspectiva de los proveedores, se encuentra cierta complementariedad que se refleja en un mayor número de asociaciones entre operadores y OTT.Propósito ”“ Una economía basada cada vez más en el Internet genera múltiples beneficios para los consumidores, pero también retos de competencia para los operadores y regulatorios para las autoridades.
Metodología ”“ El estudio considera la evolución reciente de los tres servicios tradicionales de telecomunicación, voz, mensajería y video, así como los OTT de funcionalidad similar que coexisten con ellos. Con base en la revisión bibliográfica, se analiza desde una perspectiva de la demanda, el grado de sustitución y/o complementariedad entre los servicios tradicionales y OTT.
Resultados ”“ Se encuentra que, a la fecha, no hay conclusiones contundentes, ya que bajo ciertas condiciones de consumo se observa sustitución, mientras en otras, complementariedad entre los servicios. Desde la perspectiva de los proveedores, se encuentra cierta complementariedad que se refleja en un mayor número de asociaciones entre operadores y OTT
Assessment of different plasticizer – polyhydroxyalkanoate mixtures to obtain biodegradable polymeric films
The elaboration of films from biodegradable polymer polyhydroxybutyrate was studied with 4 main plasticizers at variable concentrations: polyethyleneglycol, lauric acid, glycerol and epoxidized soy bean oil. An evaluation of the state of the art in the properties of commercial PHB (polyhydroxybutyrate) and necessary additives was elaborated in order to establish the experimental design to develop a polymeric film. Also, the qualitative evaluation of overall brittleness showed a variability due the nature and concentration of plasticizer. The influence of plasticizers on polymeric films was evaluated with gas chromatography (GC/MS) and Infrared Spectroscopy. The measurements were made on samples from different stages of the process in order to evaluate PHA (polyhydrixyalkanoate) purity. Measurements from the gas chromatography studies show the purity of the inicial fermentation broth (59.87%) , after the extraction with SDS and sodium hypochlorite (65%) and in mixtures with PEG (58.15%). From a general perspective, polyethyleneglycol (PEG) lower the material frailness and does not modify the Infra Red Spetrum as well as the Crystallinity Index (CI) in comparison with a standard commercial sample (70%+
Cómo formular una propuesta para la elaboración de un Proyecto Ambiental Escolar (PRAE) a través del estudio de las situaciones ambientales del Instituto Comercial Loreto ubicado en la localidad octava de Bogotá (Kennedy)
Los Proyectos Ambientales Escolares (PRAE) son estrategias de la educación ambiental que desde el aula y la institución escolar se vinculan a la solución integral de la problemática ambiental particular de una localidad o región. En este articulo se presenta una experiencia de investigación que muestra la formulación, construcción y desarrollo colectivo del (PRAE) con la comunidad educativa del Instituto Comercial Loreto, ubicada en la localidad octava de Bogotá (Kennedy), que parte inicialmente de una recolección de datos y descripción de las situaciones ambientales que se evidenciaron, y continúa con una metodología para identificar cuáles de éstas son las situaciones más críticas que se deben abordar, y finalmente se plantean unas alternativas de solución para las mismas. El objetivo es promover y consolidar el verdadero sentido con el que fueron propuestos y creados los (PRAE) dentro de la Política Nacional de Educación Ambiental, como herramientas fundamentales de cambio y mejoramiento de la calidad de vida de quienes se involucran estos proyectos
Efecto de la contaminación con hidrocarburo sobre la eficiencia de un sistema de inhibición
En este trabajo se evalúa un sistema de inhibición de una torre enfriadora y su comportamiento ante la presencia de un hidrocarburo como agente contaminante. Este sistema de inhibición se evaluó bajo condiciones hidrodinámicas, simulando condiciones similares a las de campo mediante el loop y el Electrodo de Cilindro Rotatorio (ECR). La velocidad de corrosión del acero AISI-SAE 1020 y admiralty fue obtenida por medio de pruebas electroquímicas (corrater, resistencia a la polarización, polarización Tafel) y pruebas gravimétricas para los diferentes ensayos (agua sin inhibidor, agua con inhibidor y contaminaciones con hidrocarburo), los resultados mostraron que el hidrocarburo puede ayudar a la protección del metal
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