Market structure and environmental amenities in hedonic pricing of rural cottages

Site-specific characteristics are attributes of tourism services for consumers and a factor influencing their costs and quality for producers. These services are a fine illustration of territorial rents. Using estimates from hedonic price equations, we test the role of environmental/territorial variables as services differentiation tools in the context of a non-competitive market, and recover the value of territorial rent generated by tourism managers' strategies. Two territories of reference are chosen, one currently benefiting from the renewed interest of the public, and a usual tourist destination. The results of a comparative analysis suggest that tourists' preferences for new destinations, combined with firms' strategies generate some catching up effect by emerging territories.ENVIRONMENTAL VALUATION; HEDONIC METHOD; SERVICE DIFFERENTIATION; TOURISM

Le rôle des cognitions environnementales dans la valorisation économique des produits et des services touristiques

Cet article présente une analyse de la différenciation des produits et services touristiques dans les espaces ruraux que nous appelons "différenciation cognitive". Il montre comment les cognitions environnementales sont à l’origine d’une interaction positive entre qualité de l’environnement et achat de produits et services touristiques de qualité. Cet ancrage environnemental crée une demande rigide pour ces produits et services liés, qui favorise l’émergence de différentiels de prix élevés, source de rentes.. La première partie montre comment la relation entre activités touristiques et services environnementaux se construit à travers les cognitions environnementales (attitude, croyances, vécu affectif). La deuxième partie met en évidence la valorisation conjointe des services environnementaux et des produits de qualité terroir dans le cas du tourisme rural dans les Baronnies à partir d’une enquête réalisée auprès de locataires et propriétaires de gîtes durant l'été 2003.TOURISME;CONSOMMATION;ENVIRONNEMENT;PRODUIT DE QUALITE;TERROIR;TERRITOIRE;SCIENCE COGNITIVE; TOURISM;CONSUMPTION;ENVIRONMENT;LOCAL QUALITY PRODUCT;TERRITORY;COGNITIVE SCIENCE

Les métamorphoses pâlissantes dans les textes traduits : étude sur le jaune et le blond.

Ante la poca atención que reciben en la producción científica en español las “figuras de traducción” (existencia de una serie de fenómenos que se repiten, independientemente de los idiomas y traductores implicados), nuestro objetivo básico es describir el proceder de los traductores cuando verbalizan lo que ven, sienten, perciben y comprenden del mundo evocado en el texto que traducen. Intentamos así aportar un esclarecimiento del fenómeno de la comprensión lectora (las reducciones realizadas por los lectores) para asentar el sentido de los enunciados literarios, y al mismo tiempo de la actividad traductora. Para ello, el artículo plantea analizar el breve espacio que da cuenta de la aprensión e identificación de los colores en el discurso mediante la revisión de la traducción del color amarillo y el matiz rubio en un corpus de textos literarios franceses y españoles (552 ítems analizados) para intentar delimitar las situaciones en las que surgen las traducciones literales de este cromatismo, y las situaciones para las que los traductores proponen distintos tipos de alejamiento, aplicando su propio “filtro de color”. Permite observar estrategias recurrentes en las alteraciones de amarillo y rubio en los textos traducidos, manifestando mayoritariamente una intensificación del realismo -que tiende a adecuar los adjetivos seleccionados a la realidad habitualmente observada (atenuación del color amarillo en determinadas situaciones: naturaleza otoñal, tez, pelo, etc.)-, o bien una respuesta (casi) automática a prácticas de lectura codificadas -preferencia de dorado como equivalente de rubio en situaciones relacionadas con objetos o elementos de la naturaleza-. Nuestra conclusión básica es que la reorganización pictórica presente en las novelas analizadas tiende a acentuar los estereotipos y los modelos realistas, en detrimento de cierta singularidad cromática propuesta por los distintos autores. Consecuentemente los traductores pierden de vista el traslado a la escritura de la imaginación creadora en los textos originales, y en las traducciones privilegian la dimensión referencial del lenguaje en detrimento de su función poética, privilegian un texto más inmediatamente legible e inteligible, designando así un tipo de discurso lícito para la lectura eficaz de enunciados ficticios

On the structure of non-full-rank perfect codes

The Krotov combining construction of perfect 1-error-correcting binary codes from 2000 and a theorem of Heden saying that every non-full-rank perfect 1-error-correcting binary code can be constructed by this combining construction is generalized to the $q$-ary case. Simply, every non-full-rank perfect code $C$ is the union of a well-defined family of $\mu$-components $K_\mu$, where $\mu$ belongs to an "outer" perfect code $C^*$, and these components are at distance three from each other. Components from distinct codes can thus freely be combined to obtain new perfect codes. The Phelps general product construction of perfect binary code from 1984 is generalized to obtain $\mu$-components, and new lower bounds on the number of perfect 1-error-correcting $q$-ary codes are presented.Comment: 8 page

Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability.

Platelet secretion not only drives thrombosis and hemostasis, but also mediates a variety of other physiological and pathological processes. The ubiquitous SNARE machinery and a number of accessory proteins have been implicated in regulating secretion in platelet. Although several platelet SNAREs have been identified, further members of the SNARE family may be needed to fine-tune platelet secretion. In this study we identified expression of the t-SNARE syntaxin 8 (STX8) (Qc SNARE) in mouse and human platelets. In mouse studies, whereas STX8 was not essential for α-granule or lysosome secretion, Stx8(-/-) platelets showed a significant defect in dense granule secretion in response to thrombin and CRP. This was most pronounced at intermediate concentrations of agonists. They also showed an aggregation defect that could be rescued with exogenous ADP and increased embolization in Stx8(-/-) mice in vivo consistent with an important autocrine and paracrine role for ADP in aggregation and thrombus stabilization. STX8 therefore specifically contributes to dense granule secretion and represents another member of a growing family of genes that play distinct roles in regulating granule release from platelets and thus platelet function in thrombosis and hemostasis

Combenefit: an interactive platform for the analysis and visualization of drug combinations.

MOTIVATION: Many drug combinations are routinely assessed to identify synergistic interactions in the attempt to develop novel treatment strategies. Appropriate software is required to analyze the results of these studies. RESULTS: We present Combenefit, new free software tool that enables the visualization, analysis and quantification of drug combination effects in terms of synergy and/or antagonism. Data from combinations assays can be processed using classical Synergy models (Loewe, Bliss, HSA), as single experiments or in batch for High Throughput Screens. This user-friendly tool provides laboratory scientists with an easy and systematic way to analyze their data. The companion package provides bioinformaticians with critical implementations of routines enabling the processing of combination data. AVAILABILITY AND IMPLEMENTATION: Combenefit is provided as a Matlab package but also as standalone software for Windows (http://sourceforge.net/projects/combenefit/). CONTACT: [email protected] SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.This work has been supported by the Cancer Research UK grant C14303/A17197This is the final version of the article. It first appeared from Oxford University Press via http://dx.doi.org/10.1093/bioinformatics/btw23