Bichromatic dressing of a quantum dot detected by a remote second quantum dot

We demonstrate an information transfer mechanism between two dissimilar remote InAs/GaAs quantum dots weakly coupled to a common photonic crystal microcavity. Bichromatic excitation in the s state of one of the dots leads to the formation of dressed states due to the coherent coupling to the laser field, in resonance with the quantum dot. Information on the resulting dressed structure is read out through the photoluminescence spectrum of the other quantum dot, as well as the cavity mode. The effect is also observed upon exchange of the excitation and detection quantum dots. This quantum dot intertalk is interpreted in terms of a cavity-mediated coupling involving acoustic phonons. A master equation for a three-level system coherently pumped by the two lasers quantitatively describes the behavior of our system. Our result presents an important step towards scalable solid-state quantum networking based on coupled multi-quantum-dot-cavity systems, without the need to use identical quantum emittersThis work was supported by the Spanish MINECO under Contract No. MAT2011-22997, by CAM under Contract No. S2009/ESP-1503, and by the FP7 ITN Spin-optronics (237252). C.S-M. and E.C. acknowledge FPI gran

Full-zirconia single-tooth molar implant-supported restorations with angulated screw channel abutments:A 1-year prospective case series study

Background Implant-supported restorations in the posterior region are subjected to various complications that could be prevented by changing either the design or the material. Purpose The aim of this prospective case series study was to evaluate full-zirconia implant-supported restorations with angulated screw channel abutments in the molar region of the maxilla and mandible and their effect on hard and soft peri-implant tissues, during a 1-year follow-up period. Materials and Methods Thirty consecutive patients with a single missing molar, sufficient bone height, and implant site free of infection were included. Each patient was to receive a parallel-walled implant with conical connection according to a two-staged surgical protocol. After 3 months, a full-contour screw-retained zirconia restoration with angulated screw channel abutment was provided. Clinical and radiographic examinations were performed 1 and 12 months after placement of the restoration. Patients' satisfaction was scored prior to treatment and after 12 months with the restoration in function. Primary outcome measure was success of the restoration. Results All patients could be evaluated after 12 months. Success of the restorations was 100%. From loading to the 12-month follow-up, the mean marginal bone loss was 0.16 mm (SD: 0.26). Mean scores for plaque, calculus, peri-implant mucosa, bleeding, and pocket probing depth were low, depicting healthy peri-implant conditions. Patients' satisfaction was high and had improved after treatment. Conclusion Full-contour zirconia implant-supported restorations with angulated screw channel abutments in the molar region have an excellent clinical performance after 1 year of function

Intraoperative in vivo confocal endomicroscopy of the glioma margin: performance assessment of image interpretation by neurosurgeon users.

OBJECTIVES Confocal laser endomicroscopy (CLE) is an intraoperative real-time cellular resolution imaging technology that images brain tumor histoarchitecture. Previously, we demonstrated that CLE images may be interpreted by neuropathologists to determine the presence of tumor infiltration at glioma margins. In this study, we assessed neurosurgeons' ability to interpret CLE images from glioma margins and compared their assessments to those of neuropathologists. METHODS In vivo CLE images acquired at the glioma margins that were previously reviewed by CLE-experienced neuropathologists were interpreted by four CLE-experienced neurosurgeons. A numerical scoring system from 0 to 5 and a dichotomous scoring system based on pathological features were used. Scores from assessments of hematoxylin and eosin (H&E)-stained sections and CLE images by neuropathologists from a previous study were used for comparison. Neurosurgeons' scores were compared to the H&E findings. The inter-rater agreement and diagnostic performance based on neurosurgeons' scores were calculated. The concordance between dichotomous and numerical scores was determined. RESULTS In all, 4275 images from 56 glioma margin regions of interest (ROIs) were included in the analysis. With the numerical scoring system, the inter-rater agreement for neurosurgeons interpreting CLE images was moderate for all ROIs (mean agreement, 61%), which was significantly better than the inter-rater agreement for the neuropathologists (mean agreement, 48%) (p < 0.01). The inter-rater agreement for neurosurgeons using the dichotomous scoring system was 83%. The concordance between the numerical and dichotomous scoring systems was 93%. The overall sensitivity, specificity, positive predictive value, and negative predictive value were 78%, 32%, 62%, and 50%, respectively, using the numerical scoring system and 80%, 27%, 61%, and 48%, respectively, using the dichotomous scoring system. No statistically significant differences in diagnostic performance were found between the neurosurgeons and neuropathologists. CONCLUSION Neurosurgeons' performance in interpreting CLE images was comparable to that of neuropathologists. These results suggest that CLE could be used as an intraoperative guidance tool with neurosurgeons interpreting the images with or without assistance of the neuropathologists. The dichotomous scoring system is robust yet simple and may streamline rapid, simultaneous interpretation of CLE images during imaging

Bichromatic dressing of a quantum dot detected by a remote second quantum dot

Maragkou, M. et al.We demonstrate an information transfer mechanism between two dissimilar remote InAs/GaAs quantum dots weakly coupled to a common photonic crystal microcavity. Bichromatic excitation in the s state of one of the dots leads to the formation of dressed states due to the coherent coupling to the laser field, in resonance with the quantum dot. Information on the resulting dressed structure is read out through the photoluminescence spectrum of the other quantum dot, as well as the cavity mode. The effect is also observed upon exchange of the excitation and detection quantum dots. This quantum dot intertalk is interpreted in terms of a cavity-mediated coupling involving acoustic phonons. A master equation for a three-level system coherently pumped by the two lasers quantitatively describes the behavior of our system. Our result presents an important step towards scalable solid-state quantum networking based on coupled multi-quantum-dot-cavity systems, without the need to use identical quantum emitters. © 2013 American Physical Society.This work was supported by the Spanish MINECO under Contract No. MAT2011-22997, by CAM under Contract No. S2009/ESP-1503, and by the FP7 ITN Spin-optronics (237252). C.S-M. and E.C. acknowledge FPI grants.Peer Reviewe

[Myositis as a post-acute sequela of COVID-19 disease? : Even in times of the pandemic, muscle biopsies can only be assessed in the context of accurate clinical information].

A case of a patient suffering from COVID-19 with suspected associated myositis is reported, in which the initially limited information about the history and disease course led to difficulties in establishing a reasonable diagnosis. Through inquiry, further data could be collected, so that the diagnosis of an infection-associated thrombotic microangiopathy in the context of a Morganella morganii myositis could be made. This patient study shows that even in times of the omnipresent pandemic and despite the context of a positive COVID-19 test result, differential diagnoses and the integrative clinicopathologic approach in interpreting muscle biopsy findings should not be neglected