Notes on Mayfly Nymphs from Northeastern Minnesota Which Key to \u3ci\u3eStenonema Vicarium\u3c/i\u3e (Ephemeroptera: Heptageniidae)

(excerpt) A review of the literature indicates that Stenonema vicarium (Walker) adults have not been collected from northeastern Minnesota. However, mayfly nymphs which key to that species, based on the descriptions in Lewis (1974), have been collected from many streams in the area which are also inhabited by nymphs of the closely related species, Stenonema fuscum (Clemens)

From customer understanding to product understanding: Collaboration with industrial lead users in a B2B context

Product innovation will continue to play a strategic role for companies producing high-quality, functional products for customers in the process industries. In the future, creating improved or radically new products will necessitate not only the development of product concepts resting more on an applied research knowledge base but also collaboration with customers. LKAB is a world-leading producer of processed iron ore products for steelmaking. The development of next-generation pellet products in collaboration with lead users presented an opportunity for a single case study in a B2B context. Two customers for present products as well as a technology/equipment supplier were identified as lead users. Using a framework grounded in lead user development, the Quality Function Deployment methodology (adapted to process-industrial use) was used as the facilitating instrument. It is concluded that this modified system will constitute an improved integrated knowledge-based platform for the development of new product and process concepts. It isargued that this development approach could also be applied in other process-industrial sectors serving industrial customers in an open innovation perspective

Relationship among religious coping, psychosocial factors, and quality of life in individuals with type 2 diabetes

The purpose of this study was to examine the relationship among religious coping, acceptance of diabetes, social support, diabetes management, and quality of life among individuals with type 2 diabetes (T2DM). Religious coping, acceptance of diabetes, and social support were hypothesized to encourage adherence to self - management behaviors thus enhancing quality of life. A convenience sample of 247 T2DM patients was recruited from local churches, clinics, a diabetes support group, and a diabetes education class. Participants completed a 10-page survey comprising the following reliable and valid scales: Religious Problem Solving Scale-Short Form, Ideas About Diabetes-Revised Scale (IAD-R), the PRQ2000, the Religious Support Scale, Summary of Diabetes Self-Care Activities-Revised, and the Diabetes Quality of Life Measure. The mean age of the respondents was 54 years, with the majority being female (68%), Caucasian (53%), and of Protestant religious affiliation (58%). Gender and ethnic differences were found for religious coping, acceptance of diabetes, and selfmanagement behaviors. African Americans and women were more religious and used more religious coping. African Americans also felt more inhibited by diabetes and women were more likely to regularly examine their feet. Gender, general social support, and feeling less inhibited by diabetes (subscale of acceptance) were significant predictors of quality of life in the multivariate (regression) analysis (F (19, 219) = 7.777, p < .001; adjusted R2 = .351). Results of this study support past research indicating the influence of gender, social support, and feeling inhibited by diabetes on respondents' quality of life. Attention to patients' level of social support and diabetes education that teaches patients how to integrate the disease into their life may be critical to improving quality of life

Rare Clinical Entity: Metastatic malignant struma ovarii diagnosed during pregnancy – Lessons for management

Abstract Background Malignant struma ovarii is an ovarian teratoma containing at least 50% thyroid tissue which has the potential to metastasize and produce thyroid hormone. Given its rarity, management strategies are not well-established. We report a case of metastatic malignant struma ovarii discovered during pregnancy with lessons for evaluation and management. Case presentation A 30-year-old woman who was two months pregnant was discovered to have struma ovarii with over half of the struma comprised of papillary thyroid cancer. Following tumor resection, delivery, and thyroidectomy, she underwent evaluation with stimulated thyroglobulin testing and diagnostic staging sodium iodide-131 scan (I-131), which revealed the presence of skeletal metastases. Following administration of 320 mCi I-131, post-therapy scan also showed miliary pulmonary metastases with improved ability to localize the bony and pulmonary metastases with concurrent SPECT/CT imaging. A second dosimetry-guided I-131 therapy resulted in complete resolution of pulmonary metastases; however, small foci of residual bone disease persisted. Post-therapy scans demonstrated additional findings not shown on diagnostic I-131 scans obtained prior to both her initial and second I-131 therapy. Conclusions SPECT/CT provides accurate anatomic correlation and localization of metastatic foci and can serve as a baseline study to assess interval response to treatment. Post-therapy scans should always be obtained when I-131 treatment is administered, as additional findings may be revealed versus low dose I-131 activity diagnostic scans. This patient had a high metastatic burden that would not have been discovered in a timely fashion with the conservative approach advocated by others. Thyroidectomy followed by a diagnostic staging radioiodine scan and a stimulated thyroglobulin level should be considered in patients with malignant struma ovarii for guiding therapeutic I-131 administration as metastatic risk is difficult to predict based on histopathologic examination.https://deepblue.lib.umich.edu/bitstream/2027.42/144518/1/40842_2018_Article_64.pd

Evolutionary characterization of pig interferon-inducible transmembrane gene family and member expression dynamics in tracheobronchial lymph nodes of pigs infected with swine respiratory disease viruses

Studies have found that a cluster of duplicated gene loci encoding the interferon-inducible transmembrane proteins (IFITMs) family have antiviral activity against several viruses, including influenza A virus. The gene family has 5 and 7 members in humans and mice, respectively. Here, we confirm the current annotation of pig IFITM1, IFITM2, IFITM3, IFITM5, IFITM1L1 and IFITM1L4, manually annotated IFITM1L2, IFITM1L3, IFITM5L, IFITM3L1 and IFITM3L2, and provide expressed sequence tag (EST) and/or mRNA evidence, not contained with the NCBI Reference Sequence database (RefSeq), for the existence of IFITM6, IFITM7 and a new IFITM1-like (IFITM1LN) gene in pigs. Phylogenic analyses showed seven porcine IFITM genes with highly conserved human/mouse orthologs known to have anti-viral activity. Digital Gene Expression Tag Profiling (DGETP) of swine tracheobronchial lymph nodes (TBLN) of pigs infected with swine influenza virus (SIV), porcine pseudorabies virus, porcine reproductive and respiratory syndrome virus or porcine circovirus type 2 over 14 days post-inoculation (dpi) showed that gene expression abundance differs dramatically among pig IFITM family members, ranging from 0 to over 3,000 tags per million. In particular, SIV upregulated IFITM1 by 5.9 fold at 3 dpi. Bayesian framework further identified pig IFITM1 and IFITM3 as differentially expressed genes in the overall transcriptome analysis. In addition to being a component of protein complexes involved in homotypic adhesion, the IFITM1 is also associated with pathways related to regulation of cell proliferation and IFITM3 is involved in immune responses

Pulse shaping of the electromagnetic radiation from a narrow slot antenna

A straightforward approach to achieve the prescribed shape of the far-field electromagnetic (EM) pulse radiated from a narrow slot antenna is introduced. It is demonstrated that the specified radiated pulse shape in a given direction can be approximately attained via a simple signal-processing technique that yields the pertaining excitation pulse. Illustrative numerical examples demonstrating good accuracy in the early-time part of the radiated pulsed fields are presented.</p

Experimental Model for Porcine Circovirus and Porcine Parvovirus Coinfection of Specific-Pathogen-Free Pigs

Porcine parvovirus (PPV) coinfection has been shown to increase the incidence and severity of porcine circovirus 2 (PCV2) associated disease in gnotobiotic and in colostrum-deprived pigs. PPV and PCV2 coinfection is also common in the grow-finish pigs in the field today. The objectives of this study were to determine the interactions between PCV2 and PPV in conventional SPF pigs and to determine whether PPV vaccine has an effect on the coinfection. Seventy-two, 6-week-old conventional pigs were inoculated either with PCV2, PPV, both PCV2 and PPV, or sham-inoculated. Before inoculation, 56 pigs were vaccinated twice with a PPV killed-virus vaccine. Clinical signs due to postweaning multisystemic wasting syndrome (PMWS) (fever, respiratory disease, jaundice, weight loss) were seen in both coinfected groups, vaccinated as well as nonvaccinated. The majority of pigs in the PCV2, and in the PCV2/PPV-inoculated groups had mild-to-severe lymphoid depletion with histiocytic replacement of follicles, and mild lymphohistiocytic interstitial pneumonia. The majority of pigs in the PCV2/PPV-coinfected groups also had mild-to-severe lymphoplasmacytic interstitial nephritis and hepatitis. There were no statistical differences between the two coinfected groups (vaccinated and non-vaccinated) in terms of clinical disease, and macroscopic and microscopic lesions. The results indicated that PPV and PCV2 coinfection resulted in increased severity of clinical disease and lymphoid lesions typical of PMWS and that a PPV-vaccination was not able to prevent PMWS in PCV2/PPV-coinfected pigs