80 research outputs found
Enhancing Security Authentication of Information System using Morse code and Facial Recognition
Information Technology Management is combination of Data Exchange, Algorithm Development, and implementation of various technologies in order to solve the problems related to Information System security. The applications of data science are used by almost all Information Systems in various domains like educational institutions, finance, healthcare, business to handle large volumes of data. The practical applications range from predicting stock movement to predicting cancer. It is used in image processing to identity recognition, audio processing for speech to text prediction. Since authentication and security of the Information System are still not completely secure and is a matter of concern, we are able to implement a real time eye-tracing along with the facial feature recognition using Morse Code based secured authentication system to enhance the Security aspects of the Information Systems. Most of the traditional Information Systems have a single layer of security authentication and cannot be relied upon. In our findings, we do not find the existing systems to be completely secure and hence we focus on implementing multiple layers of unique security authentications using eyeball movements to form a distinct Morse Code and the facial feature recognitio
Novel antibacterial activity of Terfizia claveryi aqueous extract against clinical isolates of corneal ulcer
Terfizia claveryi was examined for in vitro antibacterial activity using the disc diffusion, well diffusion method, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). T.claveryi exhibited excellent antibacterial activity against all clinical isolates of corneal ulcer tested, especially against Pseudomonas aeruginosa which showed the maximum antibacterial activity with mean zone of inhibition 20.33 mm at concentration of 100 mg/ml. The MIC for Staphylococcus aureus ranged from 0.040-1.250 mg/ml and MBC for Escherichia coli was 75 ÎŒl/ml. In the present study, the MIC value of the active aqueous extract were lower than the MBC values suggesting that, T. claveryi aqueous extracts were bacteriostatic at lower concentration but bactericidal at higher concentration. Also, the bacterial zone of inhibition increased with the increasing concentration of T. claveryi aqueous extract. To the best of our knowledge, this is the first report for the novel antibacterial activity of T.claveryi aqueous extract. This active compound may be used as alternative therapeutic drug for the control of corneal infections. However, further research is needed to examine its in vivo mechanism of action, toxicity, and therapeutic effect.Key words: Bacteria, corneal infection, antimicrobials, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), Terfizia claveryi
EFFICACY OF COMMERCIAL HOUSEHOLD INSECTICIDE AEROSOL SPRAYS AGAINST AEDES AEGYPTI (LINN.) UNDER SIMULATED FIELD CONDITIONS
Abstract. A simulated field study on the efficacy of commercial household aerosol insecticides was conducted. The bioefficacy of three pyrethroid aerosols, designated as PA1, PA2 and PA3, was tested in cabins furnished to simulate bedroom conditions. Each aerosol product was tested against lab-bred Aedes aegypti mosquitoes based on the insecticide manufacturers' recommended dosages. Ten cages with mosquitoes were placed in the following locations: one cage in the middle of the room; two each on and underneath the bed; three each placed inside, behind and on top of the wardrobe; and four placed on and in the desk. With the desk, each cage was placed inside each of three drawers (totally closed, partially closed and opened). Prior to the experiments, the discharge rate of each aerosol can was determined. Ten to 20 lab-bred 2-5 day-old sugar-fed Ae. aegypti adult mosquitoes were placed inside the test cages. The aerosol was then discharged into the cabin at the recommended dosage. After 30 minutes, the mosquitoes were transferred into clean paper cups and their mortality recorded after 24 hours. All the aerosols induced complete or very high mortality in the caged Ae. aegypti females, except in the cages hidden completely inside the drawers and wardrobes. Insecticide droplet analysis indicated variable uniformity of the droplets was produced. The aerosol insecticides were effective against mosquitoes provided they were used in accordance with the manufacturers' recommendations
Syndioselective ring-opening polymerization and copolymerization of trans-1,4-cyclohexadiene carbonate mediated by achiral metal- and organo-catalysts
International audienceThe ring-opening polymerization (ROP) of trans-1,4-cyclohexadiene carbonate (CHDC) has been investigated computationally and experimentally. DFT computations indicate that ring-opening of CHDC is thermodynamically possible, yet to a lesser extent than that of trans-cyclohexene carbonate (CHC). Effective homopolymerizations of rac-CHDC and simultaneous or sequential copolymerizations of rac-CHDC with rac-CHC and L-LA were achieved with a diaminophenolate zinc-based complex ([(NNO)ZnEt]) or a guanidine (TBD) associated with an alcohol. These ROP reactions, which confirmed the lower reactivity of rac-CHDC vs. rac-CHC, especially in homopolymerization, proceeded without any decarboxylation. Quite uniquely, highly syndiotactic PCHDC was obtained from ROP of rac-CHDC with both the zinc- and TBD-based catalysts, as revealed by 13C{1H} NMR studies. The prepared homopolymers and block or random copolymers were characterized by 1H, 13C{1H} NMR, MALDI-ToF MS, SEC and DSC techniques
Green synthesis of Piper nigrum copper-based nanoparticles: in silico study and ADMET analysis to assess their antioxidant, antibacterial, and cytotoxic effects
Nanobiotechnology is a popular branch of science that is gaining interest among scientists and researchers as it allows for the green manufacturing of nanoparticles by employing plants as reducing agents. This method is safe, cheap, reproducible, and eco-friendly. In this study, the therapeutic property of Piper nigrum fruit was mixed with the antibacterial activity of metallic copper to produce copper nanoparticles. The synthesis of copper nanoparticles was indicated by a color change from brown to blue. Physical characterization of Piper nigrum copper nanoparticles (PN-CuNPs) was performed using UV-vis spectroscopy, FT-IR, SEM, EDX, XRD, and Zeta analyzer. PN-CuNPs exhibited potential antioxidant, antibacterial, and cytotoxic activities. PN-CuNPs have shown concentration-dependent, enhanced free radical scavenging activity, reaching maximum values of 92%, 90%, and 86% with DPPH, H2O2, and PMA tests, respectively. The antibacterial zone of inhibition of PN-CuNPs was the highest against Staphylococcus aureus (23Â mm) and the lowest against Escherichia coli (10Â mm). PN-CuNPs showed 80% in vitro cytotoxicity against MCF-7 breast cancer cell lines. Furthermore, more than 50 components of Piper nigrum extract were selected and subjected to in silico molecular docking using the C-Docker protocol in the binding pockets of glutathione reductase, E. coli DNA gyrase topoisomerase II, and epidermal growth factor receptor (EGFR) tyrosine to discover their druggability. Pipercyclobutanamide A (26), pipernigramide F (32), and pipernigramide G (33) scored the highest Gibbs free energy at 50.489, 51.9306, and 58.615Â kcal/mol, respectively. The ADMET/TOPKAT analysis confirmed the favorable pharmacokinetics, pharmacodynamics, and toxicity profiles of the three promising compounds. The present in silico analysis helps us to understand the possible mechanisms behind the antioxidant, antibacterial, and cytotoxic activities of CuNPs and recommends them as implicit inhibitors of selected proteins
Theoretical calculations on the NaS and NaS
We used an ab initio methodology for the computation of the potential energy curves of
the lowest electronic states of NaS and NaS+ diatomics. Using these highly
correlated wavefunctions, we calculated their spin-orbit couplings. The X2Î and
the A2ÎŁ+ electronic states of NaS are found to possess deep potential wells. The upper bound
electronic states have either shallow potential wells located in the molecular region or
potentials of  ~1 eV depth located for large NaS distances. For NaS+,
our calculations reveal the existence of shallow potentials for all states correlating to
the four lowest dissociation limits. Using our potentials, we calculated an accurate set
of spectroscopic constants for NaS and NaS+. Most of the data relative to the
electronic excited states represent predictions. The spin-orbit induced predissociation of
NaS(A2ÎŁ+ is discussed. Finally, our
cationic potentials and the NaS(X2Î ) potential were used for the prediction of
the single ionization spectrum of NaS
Theoretical calculations on the NaS and NaS+radicals: electronic structure, spectroscopy and spin-orbit couplings
International audienceWe used an ab initio methodology for the computation of the potential energy curves of the lowest electronic states of NaS and NaS+ diatomics. Using these highly correlated wavefunctions, we calculated their spin-orbit couplings. The X2Î and the A2 ÎŁ+ electronic states of NaS are found to possess deep potential wells. The upper bound electronic states have either shallow potential wells located in the molecular region or potentials of âŒ1 eV depth located for large NaS distances. For NaS+, our calculations reveal the existence of shallow potentials for all states correlating to the four lowest dissociation limits. Using our potentials, we calculated an accurate set of spectroscopic constants for NaS and NaS+. Most of the data relative to the electronic excited states represent predictions. The spin-orbit induced predissociation of NaS(A2ÎŁ+) is discussed. Finally, our cationic potentials and the NaS(X2Î ) potential were used for the prediction of the single ionization spectrum of NaS
Tertiary palaeosurfaces of the SW Deccan, Western India: implications for passive margin uplift
Two genetically distinct lateritized palaeosurfaces of different ages are recognized in the southwest Deccan Traps region of Western India using a combination of geochemical, topographical, and satellite image data. The Deccan Traps were erupted at the Cretaceous-Tertiary boundary (c. 65 Ma), and comprise a huge area of originally near-horizontal basalt lavas covering much of northwest Peninsular India, and topographically forming the coast-parallel Western Ghats escarpment and elevated Maharashtra plateau to the east.
Remnants of the older, palaeosurface currently exist as a series of isolated, laterite-capped plateaux forming the highest elevations along the Western Ghats (15°30'â18°15' N). This surface is of late Cretaceous-early Tertiary age, and originally developed upon flows which lay at, or near to, the top of the lava sequence. This lateritization phase was terminated by a period of uplift and extensive erosion in lower- to mid-Tertiary times during which the low-lying, low-relief coastal (Konkan) plain developed through the eastward recession of the Ghats scarpline. A second phase of lateritisation occurred upon this coastal pediplain during mid- to late Tertiary times. Since the earlier uplift had gently deformed the lava pile prior to the development of the pedimented surface, the low-level Konkian laterite lies with marked angular unconformity upon the lava stratigraphy. Both surfaces have been subject to further large-scale distortion resulting from continuing uplift effects.
Development and evolution of these Deccan palaeosurfaces is important since together they provide a record of uplift effects in western India. Moreover, they offer a datum against which the uplift erosional history may be further constrained and demonstrate that uplift effects have acted upon the Indian margin throughout the Tertiary. Since such longevity of uplift is difficult to reconcile with the commonly cited thermal and dynamic post-rift mechanisms known to act upon passive margins, the morphological and structural evolution of the rifted Deccan margin is better described in terms of denudational isostasy
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