Methods of Studying False Memory

The study of memory is one of those domains in psychology which has clear practical relevance. Think, for example, about people with Alzheimer’s disease. Devastating dysfunction experienced by these patients makes it abundantly evident that our memory constitutes an overarching and critical role in our daily life. However, in the study of memory, there is another memory phenomenon that also carries with it enormous theoretical and practical implications, namely, memory illusions. That is, people frequently claim that they remember details or even an entire event that never actually happened. These false memories can have serious consequences when they appear in the testimony of witness, victims, or suspects in legal cases (Howe & Knott, 2015; Otgaar, De Ruiter, Howe, Hoetmer, & van Reekum, in press). A person, for example, might falsely remember that he/she was sexually abused when he/she was a child, and this memory illusion might lead to false accusations that may result in wrongful convictions

The Vedic Horse Sacrifice and the Changing Use of the Term ahiṃsā: An Early insertion in TB 3.9.8?

No abstrac

Quality assessments of untreated and washed quinoa (Chenopodium quinoa) seeds based on histlogical and foaming capacity investigations

Quinoa seed has a high nutritional value, but has a coating of bitter-tasting saponins, making it unpalatable. Therefore the seeds are usually processed in order to remove the naturally occurring saponins from the seeds. To investigate the impact of processing, untreated and washed seeds of the white and brown types of quinoa were investigated histologically and by foaming capacity evaluations. Reference samples of known origin and treatment were investigated as well as unknown samples. The results revealed a relationship between the presence of saponin containing papillose cells at the outermost layer of the seed hull in the histological sections and the foaming capacity of the seeds. After washing, the papillose cells were severely damaged or completely removed and virtually no foam formation was observed. This investigation indicatedthat washing resulted in an effective removal of the saponin layer, leading to quality improvement of the seeds intended for human and animal consumption. The same features were observed for the unknown samples. These results imply that the treatment of the investigated samples was based on washing. The determination of the type of treatment applied provided useful information for the correct tax classification for Custom purposes

Computersimulatie voor product- en ontwerpontwikkeling - ook voor optimalisatie

Gebouwprestatiesimulatie (GPS) wordt doorgaans alleen in de DO/TO-fase van het ontwerpproces toegepast voor toetsing aan geldende regelgeving. Toepassing van GPS als ontwerphulpmiddel in vroegere stadia van het ontwerptraject, met name bij product- en ontwerpontwikkeling van niet-beproefde concepten, kan de ontwerper echter waardevolle informatie opleveren [1]. In combinatie met optimalisatie en gevoeligheids- en onzekerheidsanalyse kan de ontwerper de risico’s en onzekerheden kwantificeren en daarmee zijn ontwerpbeslissing beter onderbouwen. Dit artikel behandelt een nieuwe methode, genaamd ‘Computational Innovation Steering (CIS)’, waarmee de risico’s en het innovatiepotentieel van innovatieve ontwerpen kunnen worden voorspeld [2]

Computational building performance simulation for integrated design and product optimization

Integrated computational building performance simulation (CBPS) can help in reducing energy consumption and increasing occupant comfort. However, the deployment of CBPS in practice has not matured and its benefits have not been fully exploited yet. This paper explores the role of CBPS in product and integrated design development and optimization through two studies. The first study explores the use of CBPS for product development within the scope of climate adaptive building shells. The second study presents a method for assisting the design innovation process, which is called ‘Computational Innovation Steering’

Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma

Basal cell carcinoma (BCC) is the most common neoplasm in the Caucasian population. Only a fraction of BCC exhibits pigmentation. Lack of melanocyte colonization has been suggested to be due to p53-inactivating mutations in the BCC cells interfering with the p53-proopiomelanocortin pathway and the production of alpha melanocyte-stimulating hormone in the tumor. To evaluate this, we determined tumor pigmentation as well as expression of melan-A and of p53 in 49 BCC tissues by means of immunohistochemistry. As expected, we observed a positive relation between tumor pigmentation and melan-A positive intra-tumoral melanocytes. Melanocyte colonization and, to a lesser extent, p53 overexpression showed intraindividual heterogeneity in larger tumors. p53 overexpression, which is indicative of p53 mutations, was not correlated to melanocyte colonization of BCC. Sequencing of exon 5–8 of the p53 gene in selected BCC cases revealed that colonization by melanocytes and BCC pigmentation is neither ablated by p53 mutations nor generally present in BCCs with wild-type p53