293 research outputs found

    Machinability study on drilling austenite stainless steel 316l1 using minimum quantity lubrication (MQL) on surface roughness

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    This research was carried out to determine the optimum condition of cutting speed, feed rate and point of angle while drilling the austenite stainless steel in order to get the good surface finish by using Minimum Quantity Lubrication (MQL). This project focuses on the drilling small hole on the austenite stainless steel by using milling machine. The aim of this project is to find the optimum condition in producing the good surface finish in drilling process with MQL. The Taguchi OA from software Minitab 16 was used to formulate the experiment, to analyze the three factors and also to predict the optimal choices of the drilling parameters. The selected cutting speeds for the drilling process are 15m/min, 25m/min and 35m/min. For the feed rate, the parameters are 0.1mm/rev, 0.15mm/rev and 0.2mm/rev. The third parameter that will be considered in this project is point of angle, and the parameters that will be used are about 110°, 120° and 135°. The machining processes were performed on the CNC milling machine. The surface roughness will be test by using Surfcom 130A. Results shows that, the best surface roughness were obtained at the lower cutting speed, middle of feed rate and middle of point of angle. So, the optimum cutting speed, feed rate and point of angle are, 15m/min, 0.15mm/rev and 120°. The confirmation results show that, the predicted values and the measured values are quite close to each other

    Altering male-dominant representations:a study on nominalized adjectives and participles in first and second language German

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    The generic use of masculine plural forms in grammatical gender languages has been criticized for activating unequal gender representations that are male dominant. The present study examined whether the recently introduced gender-neutral forms of nominalized adjectives and participles in German provide references that induce more balanced representations. We used cross-linguistic differences as a means to illustrate the flexibility of the gender representation system and investigated both native and nonnative (French–German bilinguals) speakers of German. Although a masculine bias persisted when participants read role nouns in the masculine plural form, the study suggests that the usage of nominalized forms can attenuate this male bias, even for nonnative speakers. The results of the study provide further support for the use of gender-neutral language

    Gender inferences: Grammatical features and their impact on the representation of gender in bilinguals

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    We investigated the effects of grammatical and stereotypical gender information on the comprehension of human referent role nouns among bilinguals of a grammatical (French) and a natural gender language (English). In a sentence evaluation paradigm, participants judged the acceptability of a gender-specific sentence referring to either a group of women or men following a sentence containing the plural form of a role noun female (e.g., social workers), male (e.g., surgeons) or neutral (e.g., musicians) in stereotypicality. L1 French and L1 English bilinguals were tested both in French and English. The results showed that bilinguals construct mental representations of gender associated with the language of the task they are engaged in, shifting representations as they switch languages. Specifically, in French, representations were male-dominant (i.e., induced by the masculine form), whereas in English, they were stereotype-based. Furthermore, the results showed that the extent to which representations shifted was modulated by participants' proficiency in their L2, with highly proficient L2 participants resembling native speakers of the L2 and less proficient L2 participants being influenced more by their native languag

    Yield of Outpatient Sleep EEG for Epileptiform Alterations' Detection in Children.

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    PURPOSE: Ambulatory EEGs in children are frequently ordered as sleep studies. However, the yield according to different clinical situations has received little attention to date. The authors aimed to quantify the added value in terms of detection of epileptiform features of an EEG containing sleep, as compared with only wakefulness, according to the referral diagnoses. METHODS: The authors retrospectively selected consecutive outpatients' EEG recordings of patients between 6 months to 16 years old, performed between January 2014 and February 2015. The authors excluded those lacking at least 10 minutes of waking and/or at least 5 minutes of behavioral sleep. Interictal epileptiform activity (IEA) in wakefulness and sleep was compared among referral suspected diagnoses. Additional yield of sleep was considered if at least one of the following was observed: appearance of interictal epileptiform activity or increase by >50%; interictal epileptiform activity change in localization or morphology, seizure occurrence. RESULTS: A total of 425 recordings (mean age 6.9 ± 4.7 years) were analyzed. Of them, 194 (45.6%) presented an additional yield during sleep, which was dependent on the occurrence of IEA during wakefulness: 77/251 (30.7%) in those without versus 117/174 (67.2%) in those with wakefulness IEA (P < 0.001, χ). The yield was markedly lower in studies performed for nonepileptic referral diagnoses (7% vs. 43% to 100%; P < 0.001, Fisher). CONCLUSIONS: When wakefulness EEG lacks epileptiform features, the yield of sleep EEG in our pediatric population appeared modest, especially in patients without a suspected epileptic syndrome. This information may be used to optimize the request of sleep EEG in children

    Magnetism in heavy-fermion U(Pt,Pd)3 studied by mSR

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    We report mSR experiments carried out on a series of heavy-electron pseudobinary compounds U(Pt1-xPdx)3 (x<=0.05). For x<=0.005 the zero-field muon depolarisation is described by the Kubo-Toyabe function. However the temperature variation of the Kubo-Toyabe relaxation rate does not show any sign of the small-moment antiferromagnetic phase with TN~6 K (signalled by neutron diffraction), in contrast to previous reports. The failure to detect the small ordered moment suggests it has a fluctuating (> 10 MHz) nature, which is consistent with the interpretation of NMR data. For 0.01<=x<=0.05 the muon depolarisation in the ordered state is described by two terms of equal amplitude: an exponentially damped spontaneous oscillation and a Lorentzian Kubo-Toyabe function. These terms are associated with antiferromagnetic order with substantial moments. The Knight-shift measured in a magnetic field of 0.6 T on single-crystalline U(Pt0.95Pd0.05)3 in the paramagnetic state shows two signals for B perpendicular to c, while only one signal is observed for B||c. The observation of two signals for B perpendicular to c, while there is only one muon localisation site (0,0,0), points to the presence of two spatially distinct regions of different magnetic response.Comment: 25 pages including 12 figures (PS), J. Phys.: Condens. Matter, in prin

    Magnetic quantum critical point and superconductivity in UPt3 doped with Pd

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    Transverse-field muon spin relaxation measurements have been carried out on the heavy-fermion superconductor UPt3 doped with small amounts of Pd. We find that the critical Pd concentration for the emergence of the large-moment antiferromagnetic phase is ~0.6 at.%Pd. At the same Pd content, superconductivity is completely suppressed. The existence of a magnetic quantum critical point in the phase diagram, which coincides with the critical point for superconductivity, provides evidence for ferromagnetic spin-fluctuation mediated odd-parity superconductivity, which competes with antiferromagnetic order.Comment: 4 pages (includes 3 figures); postscript fil

    Magnetic quantum critical point and superconductivity in UPt3 doped with Pd

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    Transverse-field muon spin relaxation measurements have been carried out on the heavy-fermion superconductor UPt3 doped with small amounts of Pd. We find that the critical Pd concentration for the emergence of the large-moment antiferromagnetic phase is ~0.6 at.%Pd. At the same Pd content, superconductivity is completely suppressed. The existence of a magnetic quantum critical point in the phase diagram, which coincides with the critical point for superconductivity, provides evidence for ferromagnetic spin-fluctuation mediated odd-parity superconductivity, which competes with antiferromagnetic order.Comment: 4 pages (includes 3 figures); postscript fil

    Sozialverhalten von Milchziegen in kleinen Gruppen und Folgerungen für die Strukturierung eines Laufstalls

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    Due to their rank-based relationships goats must observe a certain distance to each other (individual distance). However, this is not always possible in the limited space of a loose-housing pen and can therefore be the reason for frequent aggressive social interactions. In this study, the size of the individual distances between goats, influencing factors, modifications of the feeding place and the loose-housing pens were tested with respect to reducing aggressive behaviour. For most of the goats possible individual distances at feeding were > 0.4m. This is more than the recommended space of a feeding place per goat. Modifications of the feeding place and the loose-housing pen included solid partitions and lying niches allowing for visual cover. Another feature consisted of elevated levels by platforms at different heights. All the measures were effective in reducing aggressive behaviour

    Efficacy and tolerability of the Galanin Analog NAX 5055 in the multiple-hit rat model of symptomatic infantile spasms

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    Infantile spasms are seizures manifesting in infantile epileptic encephalopathies that are associated with poor epilepsy and cognitive outcomes. The current therapies are not always effective or are associated with serious side effects. Early cessation of spasms has been proposed to improve long-term outcomes. To identify new therapies for infantile spasms with rapid suppression of spasms, we are using the multiple-hit rat model of infantile spasms, which is a model of refractory infantile spasms. Here, we are testing the efficacy and tolerability of a single dose of the galanin receptor 1 preferring analog, NAX 5055, in the multiple-hit model of spasms. To induce the model, postnatal day 3 (PN3) male Sprague-Dawley rats underwent right intracerebral infusions of doxorubicin and lipopolysaccharide; p-chlorophenylalanine was then injected intraperitoneally (i.p.) at PN5. After the onset of spasms at PN4, 11-14 rats/group were injected i.p. with either NAX 5055 (0.5, 1, 2, or 4mg/kg) or vehicle. Video monitoring for spasms included a 1h pre-injection period, followed by 5h of recording post-injection, and two 2h sessions on PN5. The study was conducted in a randomized, blinded manner. Neurodevelopmental reflexes were assessed daily as well as at 2h after injection. Respiratory function, heart rate, pulse distension, oximetry and blood glucose were measured 4h after injection. The relative expression of GalR1 and GalR2 mRNA over β-actin in the cerebral cortex and hippocampus was determined with real time reverse transcription polymerase chain reaction. There was no acute effect of NAX 5055 on spasm frequency after the single dose of NAX 5055 (n=11-13 rats/group, following exclusions). Neurodevelopmental reflexes, vital signs, blood glucose measured 4h post-injection, and survival were not affected. A reduction in pulse and breath distention of unclear clinical significance was observed with the 7mg/kg NAX 5055 dose. GalR1 mRNA was present in the cerebral cortex and hippocampus of PN4 and adult rats. The hippocampal - but not the cortical - GalR1 mRNA expression was significantly lower in PN4 pups than in adults. GalR1 mRNA was also at least 20 times less abundant in the PN4 cortex than GalR2 mRNA. In conclusion, a single dose of NAX 5055 has no acute efficacy on spasms or toxicity in the multiple hit rat model of medically refractory infantile spasms. Our findings cannot exclude the possibility that repetitive NAX 5055 administration may show efficacy on spasms. The higher expression of GalR2 in the PN4 cortex suggests that GalR2-preferring analogs may be of interest to test for efficacy on spasms
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