1,888 research outputs found

    The Misrepresentation of Women in the Media and Women’s Rights

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    This paper is centered around the misrepresentation of women in the media and the implications that it has had on the treatment of women’s rights in society. The media is defined as television, movies, advertisements, etc. Women have been represented as being oversimplified through their stereotypical portrayal as housewives and mothers in the media, alongside being hypersexualized through their clothing and body image. Both of these forms of portrayals have had negative effects on women. Young girls are now being targeted as well through the explicit tones that the advertising of children’s toys creates. This paper aims to demonstrate how women have been disadvantaged through their stereotypical portrayal in the media and the ways in which that has led to their rights being disregarded in society. The overturning of the legal case Roe v. Wade is a prime example used in this paper to demonstrate a direct way in which women have been disadvantaged and the ways that their portrayals in the media may have led to this. This paper also aims to convince society that changes must be made to the ways that we show women in the media

    Role and Rationale for Hybrid Coronary Artery Revascularization

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    The optimal revascularization strategy for patients with multi-vessel coronary artery disease remains controversial. The advent of percutaneous coronary intervention (PCI) has challenged the superiority of coronary artery bypass graft (CABG) surgery for multi-vessel disease. In the late 1990s, an integrated approach, now referred to as “hybrid coronary revascularization” (HCR), was pioneered combining CABG and PCI to offer appropriate patients a less invasive option for revascularization while still capitalizing on the superior patency rates of the left internal mammary artery (LIMA) to the left anterior descending (LAD) artery bypass . The operative techniques continue to evolve as well as the timing strategies for intervention and use of anti-platelet therapy. While more research is needed, current data supports hybrid coronary revascularization as a promising technique to optimize outcomes in patients with multi-vessel coronary artery disease

    Genetic Diversity of Four Filipino Negrito Populations from Luzon: Comparison of Male and Female Effective Population Sizes and Differential Integration of Immigrants into Aeta and Agta Communities

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    Genetic data corresponding to four negrito populations (two Aeta and two Agta; n = 120) from the Luzon region of the Philippines have been analyzed. These data comprise mitochondrial DNA (mtDNA) hypervariable segment 1 haplotypes and haplogroups, Y-chromosome haplogroups and short tandem repeats (STRs), autosomal STRs, and X-chromosome STRs. The genetic diversity and structure of the populations were investigated at a local, regional, and interregional level. We found a high level of autosomal differentiation, combined with no significant reduction in diversity, consistent with long-term settlement of the Luzon region by the ancestors of the Agta and Aeta followed by reduced gene flow between these two ethnolinguistic groups. Collectively, the Aeta have a much higher ratio of female:male effective population size than do the Agta, a finding that supports phylogenetic analysis of their mtDNA and Y-chromosome haplogroups, which suggests different genetic sex-biased contributions from putative Austronesian source populations. We propose that factors of social organization that led to the reduction in Agta female effective population size may also be linked to the limited incorporation of female lineages associated with the settlement of the Philippines by Austronesian speakers; conversely, the reduction in Aeta male effective population size, relative to females, could be indicative of a limited incorporation of male lineages associated with this demographic process

    Justice for Injured Workers: The Struggle Continues

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    This article briefly reviews the role that community legal clinics have played in the injured worker movement. It chronicles the erosion of the basic principles of workers\u27 compensation and the shift in emphasis from compensating workers to containing costs. It exposes the myth of a debt crisis in workers\u27 compensation and explores the effect of this shift on workers\u27 benefits, on workplace health and safety, and ultimately on the viability of a no-fault, publicly-administered workers\u27 compensation system. The article also outlines the threat to the existing system in the workers\u27 compensation proposals of the current government

    Justice for Injured Workers: The Struggle Continues

    Get PDF
    This article briefly reviews the role that community legal clinics have played in the injured worker movement. It chronicles the erosion of the basic principles of workers\u27 compensation and the shift in emphasis from compensating workers to containing costs. It exposes the myth of a debt crisis in workers\u27 compensation and explores the effect of this shift on workers\u27 benefits, on workplace health and safety, and ultimately on the viability of a no-fault, publicly-administered workers\u27 compensation system. The article also outlines the threat to the existing system in the workers\u27 compensation proposals of the current government

    Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia.

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    High hyperdiploidy (HD), the most common cytogenetic subtype of B-cell acute lymphoblastic leukemia (B-ALL), is largely curable but significant treatment-related morbidity warrants investigating the biology and identifying novel drug targets. Targeted deep-sequencing of 538 cancer-relevant genes was performed in 57 HD-ALL patients lacking overt KRAS and NRAS hotspot mutations and lacking common B-ALL deletions to enrich for discovery of novel driver genes. One-third of patients harbored damaging mutations in epigenetic regulatory genes, including the putative novel driver DOT1L (n=4). Receptor tyrosine kinase (RTK)/Ras/MAPK signaling pathway mutations were found in two-thirds of patients, including novel mutations in ROS1, which mediates phosphorylation of the PTPN11-encoded protein SHP2. Mutations in FLT3 significantly co-occurred with DOT1L (p=0.04), suggesting functional cooperation in leukemogenesis. We detected an extraordinary level of tumor heterogeneity, with microclonal (mutant allele fraction <0.10) KRAS, NRAS, FLT3, and/or PTPN11 hotspot mutations evident in 31/57 (54.4%) patients. Multiple KRAS and NRAS codon 12 and 13 microclonal mutations significantly co-occurred within tumor samples (p=4.8x10-4), suggesting ongoing formation of and selection for Ras-activating mutations. Future work is required to investigate whether tumor microheterogeneity impacts clinical outcome and to elucidate the functional consequences of epigenetic dysregulation in HD-ALL, potentially leading to novel therapeutic approaches

    Two cases of monoclonal nodular pulmonary amyloidosis and review of the literature

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    Nodular pulmonary amyloidosis (NPA) is an uncommon pathology of insoluble protein depositing in pulmonary parenchyma. This localized pulmonary form of amyloidosis is most often found to contain combinations of kappa and lambda immunoglobulin light chain and immunoglobulin heavy chain proteins with a polyclonal lymphoplasmacystic infiltrate. Herein we present two cases of NPA of the rarely reported monoclonal (light-chain restricted) form with review of the literature and discussion of the clinical, radiographic, and histologic features of NPA

    PIH30 SYMPTOMS AND IMPACT OF PREMENSTRUAL DYSPHORIC DISORDER (PMDD): CONCEPTS AND MEASUREMENT

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    Landau levels and magnetopolaron effect in dilute GaAs:N

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    The magnetic-field dependence of the energy spectrum of GaAs doped with nitrogen impurities is investigated. Our theoretical model is based on the phenomenological Band Anticrossing Model (BAC) which we extended in order to include magnetic field and electron - phonon interaction. Due to the highly localized nature of the nitrogen state, we find that the energy levels are very different from those of pure GaAs. The polaron correction results in a lower cyclotron resonance energy as compared to pure GaAs. The magneto-absorption spectrum exhibits series of asymmetric peaks close to the cyclotron energy

    Hunter-Gatherer Residential Mobility and the Marginal Value of Rainforest Patches

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    The residential mobility patterns of modern hunter-gatherers broadly reflect local resource availability, but the proximate ecological and social forces that determine the timing of camp movements are poorly known. We tested the hypothesis that the timing of such moves maximizes foraging efficiency as hunter-gatherers move across the landscape. The marginal value theorem predicts when a group should depart a camp and its associated foraging area and move to another based on declining marginal return rates. This influential model has yet to be directly applied in a population of hunter-gatherers, primarily because the shape of gain curves (cumulative resource acquisition through time) and travel times between patches have been difficult to estimate in ethnographic settings. We tested the predictions of the marginal value theorem in the context of hunter-gatherer residential mobility using historical foraging data from nomadic, socially egalitarian Batek hunter-gatherers (n = 93 d across 11 residential camps) living in the tropical rainforests of Peninsular Malaysia. We characterized the gain functions for all resources acquired by the Batek at daily timescales and examined how patterns of individual foraging related to the emergent property of residential movements. Patterns of camp residence times conformed well with the predictions of the marginal value theorem, indicating that communal perceptions of resource depletion are closely linked to collective movement decisions. Despite (and perhaps because of) a protracted process of deliberation and argument about when to depart camps, Batek residential mobility seems to maximize group-level foraging efficiency
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