162 research outputs found
To What Degree do Retail Electricity Prices Inform Residential Solar Energy Investment Decisions?
The relationship between electricity price and household solar photovoltaic (PV) adoption has not been thoroughly studied. How much would a carbon tax, and increase in electricity price, spur growth in residential solar? This paper adds to the literature with a utility-level panel analysis. Consumer choice theory provides the framework for the empirical models. I use electricity price and net metered solar PV capacity data from the Energy Information Administration (EIA). Through a variety of specifications, I control for both utility and state-year effects. My findings suggest that electricity price is significantly positively correlated with solar adoption, with an estimated price elasticity of 1.85. These results are limited by endogeneity and omitted variable bias
Whose Steeple Is It? Defining the Limits of the Debtor\u27s Estate in the Religious Bankruptcy Context
A polynomial approach to topological analysis
This paper is a report of some work of Professor Kenneth Leland which may be found in his papers 1) A Polynomial Approach to Topological Analysis and 2) Topological Analysis of Analytic Functions. Section 2 of the thesis expands the development of 1) while section 3 amplifies a portion of 2)
Scanning Electron Microscopy of the Spermatheca of Plethodon Larselli (Amphibia: Plethodontidae): Changes in the Surface Morphology of the Spermathecal Tubule Prior to Ovulation
Spermathecae from eight mature female Larch Mountain salamanders (Plethodon larselli) were used to study cellular changes accompanying the administration of ovulation-inducing pregnant mare serum gonadotropin (PMSG). Animals injected daily with 25 IU of PMSG were sacrificed on day 2 or day 4. Ultrastructural alterations of the spermathecal tubules include an increase in the synthesis and release of product into the lumen and hypertrophy of two epithelial cell types by day 4. One cell type exhibits apocrine blebs and is covered with microvilli; the other contains large spherical vesicles and has only a few, short microvilli on its surface. These changes apparently reflect the spermatheca\u27s response to impending ovulation and its involvement in reactivating the stored sperm
Scanning Electron Microscopy of Chromosomes and Chromosome Fragments in Transgenic Rainbow Trout
Chromosomes and chromosome fragments from embryonic offspring of a transgenic rainbow trout were examined using scanning electron microscopy (SEM). SEM is an extremely useful technique for studying the structure of chromosome fragments since little morphological detail is revealed by conventional staining methodologies and light microscopy. The chromosome preparations were processed for SEM by combining an osmium-thiocarbohydrazide-osmium (OTO) technique with 2-4 nm of gold deposition. This technique revealed the organization of individual chromatin fibers in chromosome fragments and intact chromosomes. Both a linear chromosome fragment with a width similar to that of an intact chromatid (approximately 0.60 micrometers) and a spherical chromosome fragment with a diameter slightly greater than the width of an intact chromatid (0.66 micrometers) were observed in metaphase chromosome preparations. A connective fiber (200-300 nm in diameter) between a chromosome fragment and a host chromosome was observed. Interconnecting fibers (approximately 30 nm in diameter) between chromosomes, between chromosomes and fragments, and between sister chromatids were observed in every cell examined. We conclude that SEM permits a detailed analysis of chromosome fragment structure and the nature of chromosome-fragment associations that cannot be obtained using conventional light microscopy techniques
Vibrational Features of Water at the Low-Density/High-Density Liquid Structural Transformations
A structural transformation in water upon compression was recently observed
at the temperature ~K in the vicinity of the pressure ~Atm [R.M. Khusnutdinoff, A.V. Mokshin, J. Non-Cryst. Solids
\textbf{357}, 1677 (2011)]. It was found that the transformations are related
with the principal structural changes within the first two coordination shells
as well as the deformation of the hydrogen-bond network. In this work we study
in details the influence of these structural transformations on the vibrational
molecular dynamics of water by means of molecular dynamics simulations on the
basis of the model Amoeba potential (~K, ~Atm). The
equation of state and the isothermal compressibility are found for the
considered (,)-range. The vibrational density of states extracted for
-frequency range manifests the two distinct modes, where the
high-frequency mode is independent on pressure whereas the low-frequency one
has the strong, non-monotonic pressure-dependence and exhibits a step-like
behavior at the pressure ~Atm. The extended analysis of the
local structural and vibrational properties discovers that there is a strong
correlation between the primary structural and vibrational aspects of the
liquid-liquid structural transformation related with the molecular
rearrangement within the range of the second coordination shell.Comment: Accepted to Physica A: Statistical Mechanics and its Application
mRNA vaccine mitigates SARS-CoV-2 infections and COVID-19
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in December of 2019 and is responsible for millions of infections and deaths across the globe. Vaccination against SARS-CoV-2 has proven effective to contain the spread of the virus and reduce disease. The production and distribution of these vaccines occurred at a remarkable pace, largely through the employment of the novel mRNA platform. However, interruptions in supply chain and high demand for clinical grade reagents have impeded the manufacture and distribution of mRNA vaccines at a time when accelerated vaccine deployment is crucial. Furthermore, the emergence of SARS-CoV-2 variants across the globe continues to threaten the efficacy of vaccines encoding the ancestral virus spike protein. Here, we report results from preclinical studies on mRNA vaccines developed using a proprietary mRNA production process developed by GreenLight Biosciences. Two mRNA vaccines encoding the full-length, nonstabilized SARS-CoV-2 spike protein, GLB-COV2-042 and GLB-COV2-043, containing uridine and pseudouridine, respectively, were evaluated in rodents for their immunogenicity and protection from SARS-CoV-2 challenge with the ancestral strain and the Alpha (B.1.1.7) and Beta (B.1.351) variants. In mice and hamsters, both vaccines induced robust spike-specific binding and neutralizing antibodies, and in mice, vaccines induced significant T cell responses with a clear Th1 bias. In hamsters, both vaccines conferred significant protection following challenge with SARS-CoV-2 as assessed by weight loss, viral load, and virus replication in the lungs and nasopharynx. These results support the development of GLB-COV2-042 and GLB-COV2-043 for clinical use
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