Rationale for tau aggregation inhibitor therapy in Alzheimer's disease and other tauopathies

Preprin

Homophily, Cultural Drift and the Co-Evolution of Cultural Groups

In studies of cultural differentiation, the joint mechanisms of homophily and influence have been able to explain how distinct cultural groups can form. While these mechanisms normally lead to cultural convergence, increased levels of heterogeneity can allow them to produce global diversity. However, this emergent cultural diversity has proven to be unstable in the face of "cultural drift"- small errors or innovations that allow cultures to change from within. We develop a model of cultural differentiation that combines the traditional mechanisms of homophily and influence with a third mechanism of 2network homophily", in which network structure co-evolves with cultural interaction. We show that if social ties are allowed to change with cultural influence, a complex relationship between heterogeneity and cultural diversity is revealed, in which increased heterogeneity can reduce cultural group formation while simultaneously increasing social connectedness. Our results show that in certain regions of the parameter space these co-evolutionary dynamics can lead to patterns of cultural diversity that are stable in the presence of cultural drift.Comment: (8 pages, 8 figures

Investigation of single crystal microwave acoustical delay line materials Final report

Single crystals for microwave acoustical equipment improved by MgO dopin

Nonpartisan election formats do not affect voting behaviors

Nonpartisan elections—in which candidates are not endorsed by a political party and their party affiliation does not appear on the ballot—have been criticized as depriving crucial information to voters, making it difficult for them to vote for candidates that represent their beliefs. Chris W. Bonneau and Damon M. Cann tested the impact of nonpartisan election conditions using both a laboratory experiment and data from the Cooperative Congressional Election Survey. They find that there is no significant difference between voting behaviors in partisan and nonpartisan election formats

Magnesium oxide doping reduces acoustic wave attenuation in lithium metatantalate and lithium metaniobate crystals

Single crystals of lithium metatantalate and lithium metaniobate, grown from melts having different stoichiometries and different amounts of magnesium oxide, show that doping lowers temperature-independent portion of attenuation of acoustic waves. Doped crystals possess optical properties well suited for electro-optical and photoelastic applications