A methodology to allow avalanche forecasting on an information retrieval system

This paper presents adaptations and tests undertaken to allow an information retrieval (IR) system to forecast the likelihood of avalanches on a particular day. The forecasting process uses historical data of the weather and avalanche conditions for a large number of days. A method for adapting these data into a form usable by a text-based IR system is first described, followed by tests showing the resulting system’s accuracy to be equal to existing ‘custom built’ forecasting systems. From this, it is concluded that the adaptation methodology is effective at allowing such data to be used in a text-based IR system. A number of advantages in using an IR system for avalanche forecasting are also presented

Long-term Outcome after Surgical Closure of Atrial Septal Defect in Childhood with Extensive Assessment Including MRI Measurement of the Ventricles

Surgical closure of the secundum type of atrial septal defect (ASD) in childhood leads to excellent survival. However, relevant morbidity has been reported. Transcatheter closure of these defects has now become an alternative approach. To compare the results of the two different interventions, reliable data are needed on the long-term morbidity after defect closure with both methods. Patients were evaluated after a minimum of 10 years after surgical closure of an ASD in childhood. Assessment included analysis of perioperative data, interview, clinical examination, electrocardiogram, (ECG), 24-hour ECG, ergometry, chest radiograph, echocardiography, and MRI. A total of 66 patients underwent operation between 1971 and 1986 at our institution. Forty-eight of them (73%) were interviewed and 38 (58%) participated fully in the study program. Eighteen (27%) either refused to participate or were lost to follow-up. There were no substantial residual disorders, such as arrhythmias, right-sided heart dilatation, pulmonary hypertension, or reduced work capacity. Surgical closure of an ASD in childhood has an excellent long-term outcome. Surgical closure is thus the standard against which transcatheter closure needs to be measure

Bayesian multi-model projection of climate: bias assumptions and interannual variability

Current climate change projections are based on comprehensive multi-model ensembles of global and regional climate simulations. Application of this information to impact studies requires a combined probabilistic estimate taking into account the different models and their performance under current climatic conditions. Here we present a Bayesian statistical model for the distribution of seasonal mean surface temperatures for control and scenario periods. The model combines observational data for the control period with the output of regional climate models (RCMs) driven by different global climate models (GCMs). The proposed Bayesian methodology addresses seasonal mean temperatures and considers both changes in mean temperature and interannual variability. In addition, unlike previous studies, our methodology explicitly considers model biases that are allowed to be time-dependent (i.e. change between control and scenario period). More specifically, the model considers additive and multiplicative model biases for each RCM and introduces two plausible assumptions ("constant bias” and "constant relationship”) about extrapolating the biases from the control to the scenario period. The resulting identifiability problem is resolved by using informative priors for the bias changes. A sensitivity analysis illustrates the role of the informative prior. As an example, we present results for Alpine winter and summer temperatures for control (1961-1990) and scenario periods (2071-2100) under the SRES A2 greenhouse gas scenario. For winter, both bias assumptions yield a comparable mean warming of 3.5-3.6°C. For summer, the two different assumptions have a strong influence on the probabilistic prediction of mean warming, which amounts to 5.4°C and 3.4°C for the "constant bias” and "constant relation” assumptions, respectively. Analysis shows that the underlying reason for this large uncertainty is due to the overestimation of summer interannual variability in all models considered. Our results show the necessity to consider potential bias changes when projecting climate under an emission scenario. Further work is needed to determine how bias information can be exploited for this tas

M-grid: Using Ubiquitous Web Technologies to create a Computational Grid

There are many potential users and uses for grid computing. However, the concept of sharing computing resources excites security concerns and, whilst being powerful and flexible, at least for novices, existing systems are complex to install and use. Together these represent a significant barrier to potential users who are interested to see what grid computing can do. This paper describes m-grid, a system for building a computational grid which can accept tasks from any user with access to a web browser and distribute them to almost any machine with access to the internet and manages to do this without the installation of additional software or interfering with existing security arrangements

Remifentanil does not impair left ventricular systolic and diastolic function in young healthy patients

Background Experimental studies and investigations in patients with cardiac diseases suggest that opioids at clinical concentrations have no important direct effect on myocardial relaxation and contractility. In vivo data on the effect of remifentanil on myocardial function in humans are scarce. This study aimed to investigate the effects of remifentanil on left ventricular (LV) function in young healthy humans by transthoracic echocardiography (TTE). We hypothesized that remifentanil does not impair systolic, diastolic LV function, or both. Methods Twelve individuals (aged 18-48 yr) without any history or signs of cardiovascular disease and undergoing minor surgical procedures under general anaesthesia were studied. Echocardiographic examinations were performed in the spontaneously breathing subjects before (baseline) and during administration of remifentanil at a target effect-site concentration of 2 ng ml−1 by target-controlled infusion. Analysis of systolic function focused on fractional area change (FAC). Analysis of diastolic function focused on peak early diastolic velocity of the mitral annulus (e′) and on transmitral peak flow velocity (E). Results Remifentanil infusion at a target concentration of 2 ng ml−1 did not affect heart rate or arterial pressure. There was no evidence of systolic or diastolic dysfunction during remifentanil infusion, as the echocardiographic measure of systolic function (FAC) was similar to baseline, and measures of diastolic function remained unchanged (e′) or improved slightly (E). Conclusion Continuous infusion of remifentanil in a clinically relevant concentration did not affect systolic and diastolic LV function in young healthy subjects during spontaneous breathing as indicated by TT

Isospectral domains with mixed boundary conditions

We construct a series of examples of planar isospectral domains with mixed Dirichlet-Neumann boundary conditions. This is a modification of a classical problem proposed by M. Kac.Comment: 9 figures. Statement of Theorem 5.1 correcte

All-Sky spectrally matched UBVRI-ZY and u'g'r'i'z' magnitudes for stars in the Tycho2 catalog

We present fitted UBVRI-ZY and u'g'r'i'z' magnitudes, spectral types and distances for 2.4M stars, derived from synthetic photometry of a library spectrum that best matches the Tycho2 BtVt, NOMAD Rn and 2MASS JHK_{2/S} catalog magnitudes. We present similarly synthesized multi-filter magnitudes, types and distances for 4.8M stars with 2MASS and SDSS photometry to g<16 within the Sloan survey region, for Landolt and Sloan primary standards, and for Sloan Northern (PT) and Southern secondary standards. The synthetic magnitude zeropoints for BtVt, UBVRI, ZvYv, JHK_{2/S}, JHK_{MKO}, Stromgren uvby, Sloan u'g'r'i'z' and ugriz are calibrated on 20 calspec spectrophotometric standards. The UBVRI and ugriz zeropoints have dispersions of 1--3%, for standards covering a range of color from -0.3 < V-I < 4.6; those for other filters are in the range 2--5%. The spectrally matched fits to Tycho2 stars provide estimated 1-sigma errors per star of ~0.2, 0.15, 0.12, 0.10 and 0.08 mags respectively in either UBVRI or u'g'r'i'z'; those for at least 70% of the SDSS survey region to g<16 have estimated 1-sigma errors per star of ~0.2, 0.06, 0.04, 0.04, 0.05 in u'g'r'i'z' or UBVRI. The density of Tycho2 stars, averaging about 60 stars per square degree, provides sufficient stars to enable automatic flux calibrations for most digital images with fields of view of 0.5 degree or more. Using several such standards per field, automatic flux calibration can be achieved to a few percent in any filter, at any airmass, in most workable observing conditions, to facilitate inter-comparison of data from different sites, telescopes and instruments.Comment: 36 pages, 30 figures, 3 printed tables, several electronic tables, accepted PASP Dec 201

Different effects of sevoflurane, desflurane, and isoflurane on early and late left ventricular diastolic function in young healthy adults†

Background Knowledge on the effects of volatile anaesthetics on left ventricular (LV) diastolic function in humans in vivo is limited. We tested the hypothesis that sevoflurane, desflurane, and isoflurane do not impair LV diastolic function in young healthy humans. Methods Sixty otherwise healthy subjects (aged 18-48 yr) undergoing minor procedures under general anaesthesia were studied. After randomization for the anaesthetic, transthoracic echocardiographic examinations were performed at baseline and under anaesthesia with 1 minimum alveolar concentration (MAC) of the volatile anaesthetics during spontaneous breathing and intermittent positive pressure ventilation (IPPV). Peak early (E′) and late (A′) diastolic velocities of the mitral annulus were studied as the main echocardiographic indicators of diastolic function. Results During anaesthesia with 1 MAC under spontaneous breathing, E′ increased with desflurane (P<0.001), was not significantly different with isoflurane (P=0.030), and decreased with sevoflurane (P=0.006). During IPPV, E′ was similar to baseline with desflurane (P=0.550), insignificantly decreased with isoflurane (P=0.029), and decreased with the sevoflurane group (P<0.001). In contrast, A′ was similarly reduced in all groups during spontaneous breathing without further changes during IPPV. Haemodynamic changes were comparable in all study groups. Conclusions The findings of this in vivo study indicate that desflurane and isoflurane, and most likely sevoflurane, have no relevant direct negative effect on early diastolic relaxation in young healthy humans. In contrast, all three volatile anaesthetics appear to impair late diastolic LV filling during atrial contraction. Trial Registration #: NCT002445

Statistical properties of the GALEX spectroscopic stellar sample

The GALEX General Data Release 4/5 includes 174 spectroscopic tiles, obtained from slitless grism observations, for a total of more than 60,000 ultraviolet spectra. We have determined statistical properties of the sample of GALEX stars. We have defined a suitable system of spectroscopic indices, which measure the main mid-UV features at the GALEX low spectral resolution and we have employed it to determine the atmospheric parameters of of stars in the range 4500<Teff<9000 K. Our preliminary results indicate that the sample is formed by a majority of main sequence F- and G-type stars, with metallicity [M/H]>-1 dex.Comment: 9 pages, 9 figures, accepted for publication in Astrophysics & Space Science, UV universe special issu

Scalar fields on SL(2,R) and H^2 x R geometric spacetimes and linear perturbations

Using appropriate harmonics, we study the future asymptotic behavior of massless scalar fields on a class of cosmological vacuum spacetimes. The spatial manifold is assumed to be a circle bundle over a higher genus surface with a locally homogeneous metric. Such a manifold corresponds to the SL(2,R)-geometry (Bianchi VIII type) or the H^2 x R-geometry (Bianchi III type). After a technical preparation including an introduction of suitable harmonics for the circle-fibered Bianchi VIII to separate variables, we derive systems of ordinary differential equations for the scalar field. We present future asymptotic solutions for these equations in a special case, and find that there is a close similarity with those on the circle-fibered Bianchi III spacetime. We discuss implications of this similarity, especially to (gravitational) linear perturbations. We also point out that this similarity can be explained by the "fiber term dominated behavior" of the two models.Comment: 23 pages, no figures, to be published in Class. Quant. Gravi