4,283 research outputs found
Effect of the stop-signal modality on brain electrical activity associated with suppression of ongoing actions
To clarify how the modality of stop signals affects the ability to suppress ongoing actions, we compared behavioural indices and event-related potentials (ERPs) recorded in healthy volunteers performing visual and auditory stop-signal tasks. Auditory stop signals were associated with faster reaction times and shorter stop-N2 and stop-P3 latencies. Given that the tasks did not differ in attentional/arousal processes (go-P3 or stop-P3 amplitudes) or motor preparation (LRP amplitude, onset or latency), our results suggest that stop signal modality mainly affects bottom-up sensory processes (faster auditory processing). The ERP waveform obtained by subtracting successfully stopped from unsuccessfully stopped trials showed similar amplitude and topography in both tasks, indicating that the strength of top-down processes related to inhibition was independent of modality. The findings contribute further knowledge about the variables associated with efficient inhibition and have practical implications for the design of settings or interventions to improve reactive inhibition.This work was supported by funding from the Galician Government (Consellería de Cultura, Educación e Ordenación Universitaria; axudas para a consolidación e Estruturación de unidades de investigación competitivas do Sistema universitario de Galicia [grant number GPC2014/047]. A.J. G-V was supported by a grant from the Deputación da Coruña (Bolsas de investigación en ciencias da saúde 2017) and
Xunta de Galicia (Axudas de apoio á etapa de formación posdoutoral 2018)
Pain expressions and inhibitory control in patients with fibromyalgia: behavioral and neural correlates
Fibromyalgia (FM) is a generalized chronic pain condition associated with a variety of symptoms, including altered cognitive and emotional processing. It has been proposed that FM patients show a preferential allocation of attention to information related to the symptoms of the disease, particularly to pain cues. However, the existing literature does not provide conclusive evidence on the presence of this attentional bias, and its effect on cognitive functions such as inhibitory control. To clarify this issue, we recorded the electroencephalographic activity of 31 women diagnosed with FM and 28 healthy women, while performing an emotional Go/NoGo task with micro-videos of pain, happy, and neutral facial expressions. We analyzed behavioral data, performed EEG time-frequency analyses, and obtained the event-related potentials (ERPs) N2 and P3 components in NoGo trials. A series of self-reports was also administered to evaluate catastrophic thinking and the main symptoms of fibromyalgia. Pain expressions were associated with longer reaction times and more errors, as well as with higher theta and delta power, and P3 amplitude to NoGo stimuli. Thus, behavioral and psychophysiological data suggest that increased attention to pain expressions impairs the performance of an inhibitory task, although this effect was similar in FM patients and healthy controls. N2 amplitude was modulated by type of facial expression (larger to pain faces), but only for the control group. This finding suggests that the presentation of pain faces might represent a smaller conflict for the patients, more used to encounter pain stimuli. No main group effects were found significant for N2 or P3 amplitudes, nor for time-frequency data. Using stimuli with greater ecological validity than in previous studies, we could not confirm a greater effect of attentional bias toward negative stimuli over inhibitory performance in patients with FM. Studying these effects allow us to better understand the mechanisms that maintain pain and develop intervention strategies to modify them.Galician
Government (Consellería de Cultura, Educación e Ordenación
Universitaria; axudas para a consolidación e estruturación
de unidades de investigación competitivas do Sistema
Universitario de Galicia [grant number GPC2014/047] and
funding from the Spanish Government (Ministerio de Economía
y Competitividad) [grant number PSI2013-45818-R]. AG-V was
supported by a grant from the Deputación da Coruña (Bolsas de
investigación en ciencias da saúde 2017) and Xunta de Galici
Neural correlates of cognitive dysfunction in fibromyalgia patients: Reduced brain electrical activity during the execution of a cognitive control task
Fibromyalgia (FM) is a generalized chronic pain syndrome of unknown aetiology. Although FM patients frequently complain of cognitive dysfunction, this is one of the least studied symptoms. Research on brain activity associated with the perceived cognitive impairment is particularly scarce. To address this gap, we recorded the brain electrical activity in participants during a cognitive control task.This study was supported by funding from from the Spanish Government (Ministerio de Economia y Competitividad; grant number PSI2013-45818-R] and from the Galician Government (Conselleria de Cultura, Educacion e Ordenacion Universitaria; axudas para a consolidacion e Estruturacion de unidades de investigacion competitivas do Sistema universitario de Galicia; grant number GPC 2014/047). A.G.V. was supported by a grant from Xunta de Galicia (Axudas de apoio a etapa de formacion posdoutoral 2018)
Noninvasive mechanical ventilation (NIMV) in weaning failure: could be an alternative approach?
Effects of mask-ventilator interface elements in a home noninvasive portable ventilator. Study in cold hypercapnic patients
Noninvasive mechanical ventilation in asthma crisis: an alternative ventilatory therapy to endotracheal intubation
Bioelectrochemical enhancement of methane production from exhausted vine shoot fermentation broth by integration of MEC with anaerobic digestion
[ES] A microbial electrolysis cell integrated in an anaerobic digestion system (MEC-AD) is an efficient configuration to produce methane from an exhausted vine shoot fermentation broth (EVS). The cell worked in a single-chamber two-electrode configuration at an applied potential of 1 V with a feeding ratio of 30/70 (30% EVS to 70% synthetic medium). In addition, an identical cell operated in an open circuit was used as a control reactor. Experimental results showed similar behavior in terms of carbon removal (70–76%), while the specific averaged methane production from cycle 7 was more stable and higher in the connected cell (MECAD) compared with the unpolarized one (OCAD) accounting for 403.7 ± 33.6 L CH4·kg VS−1 and 121.3 ± 49.7 L CH4·kg VS−1, respectively. In addition, electrochemical impedance spectroscopy revealed that the electrical capacitance of the bioanode in MECAD was twice the capacitance shown by OCAD. The bacterial community in both cells was similar but a clear adaptation of Methanosarcina Archaea was exhibited in MECAD, which could explain the increased yields in CH4 production. In summary, the results reported here confirm the advantages of integrating MEC-AD for the treatment of real organic liquid waste instead of traditional AD treatment.SIPublicación en abierto financiada por el Consorcio de Bibliotecas Universitarias de Castilla y León (BUCLE), con cargo al Programa Operativo 2014ES16RFOP009 FEDER 2014-2020 DE CASTILLA Y LEÓN, Actuación:20007-CL - Apoyo Consorcio BUCL
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