Desvictimizar : recuperando memoria de dos generaciones en el rescate de fortalezas y resiliencias resistentes durante dictadura militar en Chile

En primer lugar, en esta investigación me posiciono como investigadora comprometida y desde una propuesta epistemológica de un conocimiento situado (Haraway, 1995), que además de serlo está “enraizado, afectado y cotidiano porque genera un compromiso que se traduce en acción concreta que necesita entregar para poder existir" (León 2010, p. 6). Se trata de recordar, conocer y comprender en forma reflexiva, otros diseños de vida y de país que quedaron truncos, pero no aniquilados. Es así como el objetivo general fue investigar y analizar mediante el tejido de la memoria y desde una perspectiva desvictimizadora, experiencias y vivencias de un grupo de mujeres durante su permanencia en la cárcel y/o exilio; así como la de nuestras/os hijos e hijas nacidos/as dentro y fuera de Chile durante la dictadura militar, 11 de septiembre de 1973 a marzo de 1990. Lo relevante de este estudio fue rescatar fortalezas y recursos personales que utilizamos dos generaciones en nuestras vidas cotidianas. Investigación que dio cuenta y cuestionó, desde el imaginario personal, social y colectivo, implicaciones y presupuestos establecidos sobre el concepto de víctima de violencia política. Fue un trabajo de investigación tejido con las voces del pasado en el presente y con proyección al futuro. De ahí radica la importancia de rescatar las vivencias de las luchadoras sociales de esos tiempos y ponerlos en relación con lo que hacemos hoy día. También se trata de dar cuenta en qué están hoy nuestras/os hijas/os.Fil: Benavides Andrades, María Angélica. Universidad Autónoma de BarcelonaFil: Cantera E., Leonor M.. Universidad Autónoma de BarcelonaFil: Alvarado, Patricia. Universidad Autónoma de Barcelon

Supplementing nursery pig feed with seaweed extracts increases final body weight of pigs

Probiotics have been used as an alternative method to antibiotic treatment. In this study, we evaluated the effect of seaweed extracts, commercially named OceanFeed Swine® (OFS), on body weight, average daily weight gain (ADG) and feed efficiency (FE) in nursery and fattening pigs of terminal lines. The study was conducted with 1809 piglets from weaning age until the end of the fattening phase on a commercial farm, divided into two groups (control and OFS; 905 and 904 pigs, respectively). Three replicates were made during the 6 weeks of production. Food was elaborated in the same productive unit and was given to the animals in the form of flour. OceanFeed Swine® (5 g/kg of diet) was added to the diet of the OFS groups during the nursery period, from 21 to 55 days of age. The faecal microbial population was evaluated at 35 and 60 days of life. In this paper, we observed a positive effect of administering OceanFeed Swine® on the production parameters analysed in the fattening phase, showing an improvement of 26 g in ADG and FE of 0.07. It can be concluded that the use of OceanFeed Swine® in the diets of the piglets, aged between 21 to 55 days old, improves FE (Control 2.36, OFS 2.29) and ADG (control 0.798 kg, OFS 0.824 kg). Moreover, its use exhibited an increase in the slaughter weight, a reduction of E coli CFU, and an increase in Lactobacillus sp. in fattening animals. All these improvements have a major positive economic impact per pig at time of slaughter

Are our people health conscious? results of a patients survey in Karachi, Pakistan

BACKGROUND: Life style is known to influence health and may be responsible for certain diseases. There is a need to document the life style on health among the Pakistani population. METHODS: The study was conducted on patients visiting the Family Practice Center, the Aga Khan University, Karachi. A questionnaire was used to collect information on the demographic profile, and the life style on health. The ethical requirements for conducting the study were met. RESULTS: 393 patients were surveyed. The majority were young married men, in either private or government service. Preference for consumption of fats/oils, sweets, spicy foods, salt, fruits/vegetables, tea, coffee, cola drinks and alcohol was found among 103 (26%), 84 (22%), 86 (22%), 110 (28%), 239 (61%), 319 (81%), 117 (30%), 253 (64%) and 13 (03%) respondents respectively. Hand washing after defecation, before eating food and after work was seen among 341 (87%), 296 (75%) and 256 (65%) respondents respectively. Brushing of teeth after eating food, before breakfast and bedtime was seen in 56 (14%), 346 (88%) and 176 (45%) respondents respectively. Preventive dental check-up was practiced by 102 (26%) of the respondents. Sleep of less than 6 hours per day among 74 (19%), water consumption of less than 1 liter daily among 84 (21%) and fish consumption on once a week basis among 173 (44%) respondents was found. Tobacco and betel nuts use was found among 69 (17%) and 79 (20%) respondents. CONCLUSIONS: We have documented a clear need to raise public awareness on the issue of life style on health. There is a need and we strongly recommend debate and further research, along with interventional strategies in line with the available evidence on healthy life style

Structure-activity relationships based on 3D-QSAR CoMFA/CoMSIA and design of aryloxypropanol-amine agonists with selectivity for the human β3-adrenergic receptor and anti-obesity and anti-diabetic profiles

Indexación: Scopus.Acknowledgments: This work was supported by FONDECYT No. 11130701. We would also like to thank fDoTr CthLeafbr efeora vthaeil afrbeilei tayvoafiltahbeilsitoyf towfa trheer seoqfutwireadret orecqaulciureladt etothcealAcuDla(thet ttph:e/ A/dDt c(lhatbt.pw:/e/dbstc.cloabm.w/seobfst.wcoamre/-stoofotlws aarned-tools and http://teqip.jdvu.ac.in/QSAR_Tools/). SDG. Conflicts of Interest: The authors declare no conflict of interest. Conflicts of Interest: The authors declare no conflict of interest.The wide tissue distribution of the adrenergic β3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there is only one drug on the market, mirabegron, approved for the treatment of OAB. In the present study, we have carried out an extensive structure-activity relationship analysis of a series of 41 aryloxypropanolamine compounds based on three-dimensional quantitative structure-activity relationship (3D-QSAR) techniques. This is the first combined comparative molecular field analysis (CoMFA) and comparative molecular similarity index analysis (CoMSIA) study in a series of selective aryloxypropanolamines displaying anti-diabetes and anti-obesity pharmacological profiles. The best CoMFA and CoMSIA models presented values of r2 ncv = 0.993 and 0.984 and values of r2 test = 0.865 and 0.918, respectively. The results obtained were subjected to extensive external validation (q2, r2, r2 m, etc.) and a final series of compounds was designed and their biological activity was predicted (best pEC50 = 8.561). © 2018 by the authors.https://www.mdpi.com/1420-3049/23/5/119

Distribution of lower urinary tract symptoms (LUTS) in adult women

OBJECTIVE: To determine the distribution of lower urinary tract symptoms in adult women and the frequency with which the women consulted a health care provider for their symptoms. DESIGN: Cross-sectional analytical study. PLACE AND DURATION OF STUDY: Community Health Center of Aga Khan University Hospital from November 1st to 30th, 2002. SUBJECTS AND METHODS: A trained interviewer administered a structured questionnaire to women patients or attendants aged 18 years and older coming to the center. RESULTS: Fifty-two percent of the study subjects reported having at least one or more urinary complaints in the past. Stress incontinence was the highest reported complaint (38.4%) followed by burning (34.4%), frequency (26%), painful micturition (20.4%), urge incontinence (18.8 %), incomplete emptying of bladder (14.4%), dribbling (12.4%) and poor stream (8.4%). Forty-three percent of the women with LUTS never consulted a health care provider for their problem.CONCLUSION: Although the distribution of LUTS among females was found to be high, the patients did not consider it important enough to consult a health care provider. There is a need to create awareness among females regarding LUTS and the need to consult a health care provider for their problems

A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections

Indexación: Scopus.A rapid emergence of resistant bacteria is occurring worldwide, endangering the efficacy of antibiotics and reducing the therapeutic arsenal available for treatment of infectious diseases. In the present study, we developed a new class of compounds with antibacterial activity obtained by a simple, two step synthesis and screened the products for in vitro antibacterial activity against ATCC® strains using the broth microdilution method. The compounds exhibited minimum inhibitory concentrations (MIC) of 1⁻32 μg/mL against Gram-positive ATCC® strains. The structure⁻activity relationship indicated that the thiophenol ring is essential for antibacterial activity and the substituents on the thiophenol ring module, for antibacterial activity. The most promising compounds detected by screening were tested against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VREF) clinical isolates. We found remarkable activity against VREF for compounds 7 and 16, were the MIC50/90 were 2/4 µg/mL and 4/4 µg/mL, respectively, while for vancomycin the MIC50/90 was 256/512 µg/mL. Neither compound affected cell viability in any of the mammalian cell lines at any of the concentrations tested. These in vitro data show that compounds 7 and 16 have an interesting potential to be developed as new antibacterial drugs against infections caused by VREF.https://www.mdpi.com/1420-3049/23/7/177

Niche-Relationships Within and Among Intertidal Reef Fish Species

Niche-related processes (e.g., density or niche-breadth compensation and competition) are fundamental to a broad understanding of community ecology and ecosystem functioning. Most evidences of competition are from controlled indoor trials with few species, and it remains a challenge to estimate competition among multiple species in the field. Here, we analyze stable isotopes and distributional data from 51 fish taxa in six locations in the southwestern Atlantic to predict intraspecific trophic pressure (ITP) and the potential competitive strength among species in a trophic-based framework. We used two proxies built upon 2-dimensional isotopic space (δ13C vs. δ15N), its predicted overlap, and fish density to calculate winner and loser taxa in potential paired interspecific competitive interactions. The intraspecific proxy indicated that cryptobenthic fishes are under high among-individual trophic pressure (high densities and small niche sizes). Also, cryptobenthic behavior together with feeding specialization and extremely small-sizes were the most important traits related to low success in interspecific simulations. Although cryptobenthic fishes face strong competitive pressures, there are some known inherent trade-offs to cryptobenthic life such as trophic and habitat use specializations. These seem to compensate and ensure coexistence among cryptobenthic fishes and non-cryptobenthic species. Habitat loss/degradation via urbanization, invasive species and climate-change-driven sea-level rise can reduce the suitability of habitat and increase competition on cryptobenthic species, especially in shallow reefs and intertidal shores

Characterization of non‑linear mechanical behavior of the cornea

The objective of this study was to evaluate which hyperelastic model could best describe the nonlinear mechanical behavior of the cornea, in order to characterize the capability of the non-linear model parameters to discriminate structural changes in a damaged cornea. Porcine corneas were used, establishing two diferent groups: control (non-treated) and NaOH-treated (damaged) corneas (n= 8). NaOH causes a chemical burn to the corneal tissue, simulating a disease associated to structural damage of the stromal layer. Quasi-static uniaxial tensile tests were performed in nasaltemporal direction immediately after preparing corneal strips from the two groups. Three non-linear hyperelastic models (i.e. Hamilton-Zabolotskaya model, Ogden model and Mooney-Rivlin model) were ftted to the stress–strain curves obtained in the tensile tests and statistically compared. The corneas from the two groups showed a non-linear mechanical behavior that was best described by the Hamilton-Zabolotskaya model, obtaining the highest coefcient of determination (R2 > 0.95). Moreover, Hamilton-Zabolotskaya model showed the highest discriminative capability of the nonlinear model parameter (Parameter A) for the tissue structural changes between the two sample groups (p= 0.0005). The present work determines the best hyperelastic model with the highest discriminative capability in description of the non-linear mechanical behavior of the cornea.Ministry of Education DPI2017-83859-R DPI2014-51870-R EQC2018004508-P UNGR15-CE-3664Ministry of Health - Turkey DTS15/00093Junta de Andalucia PI16/00339 PI-0107-2017 PIN-0030-201

Comparative evaluation of therapeutic interventions during hemorrhagic shock

Trabalho apresentado ao 31º International Symposium on Intensive Care and Emergency Medicine, 2011, Bruxelas

OntoEPFS: uma ontologia para experimentos em mapeamento digital de solos.

A descrição formal de experimentos para aquisição, tratamento, análises de dados, compartilhamento e reprodução dos resultados obtidos é fundamental para os cientistas envolvidos. Ontologias vêm sendo utilizadas para criar modelos formais para disseminação de informação e conhecimento. Este artigo apresenta uma ontologia para apoiar o Experimento de Predição de Informações de Fertilidades de Solos (OntoEPFS) em Mapeamento Digital de Solos (DSM). O EPFS se encontra em desenvolvimento na Empresa Brasileira de Pesquisa Agropecuária, no Centro Nacional de Pesquisa em Solos ? Embrapa Solos. A adoção dessa ontologia, por parte da Embrapa Solos, facilitará a descrição, a formalização e a disponibilização de conhecimentos sobre os experimentos realizados por esta unidade.SBIAgro 2009