Amine-terminated nanoparticle films: pattern deposition by a simple nanostencilling technique and stability studies under X-ray irradiation

Exploring the surface chemistry of nanopatterned amine-terminated nanoparticle films.</p

Analysis of prescription pattern of anemia in pregnancy: an observational, cross-sectional study

Background: Anemia is a major health problem that affects 25% to 50% of the population of the world and approximately 50% of pregnant women. This research on the use of prescription medicines in anemia during pregnancy remains critically important. Prescribing patterns of the drug in the pregnant women include age, trimester, gravid condition, US-FDA risk category, WHO core indicators.Methods: A prospective, cross sectional observational multicentric study was conducted in outpatient and inpatient departments of Indira Gandhi Hospital and Civil Hospital in Nasik, for period of 6 months. Ethical approval was taken prior to study from Independent ethics committee. A total of 197 patients were enrolled in the study. Inform consent form was obtained from the patients. After studying them; statistical analysis were done and result and conclusion were drawn.Results: Out of 197 women’s prescriptions, the average number of drug per prescription was 2.14. 27.28% drugs were prescribed there brand name and 72.72% by generic name. Iron, folic acid and calcium were prescribed to all pregnant women. The majority of the patients were prescribed category A and category C drugs. No patients were given category X drug.Conclusions: Nearly all prescription showed a prescribing practice for writing prophylactic iron and folic acid therapy in all pregnant women. No women was prescribed category X drug. Most of the drug prescribed in generics and thus, prescription pattern of our study set a fine example of prescribing behaviour

Methodology to Aircraft Design – Market Study & Design Optimization

In the last few years Aircraft have grown to be large-scale products with an increasing number of complicated systems, components, parts, and capabilities. Every single one of them. Various fields and technologies are included. Multiple sets of tools, procedures and methods are also included, as a result, to fully define, design, and develop an aircraft A comprehensive and methodic approach is required. Aircraft design that serves as a pillar in the evolution of the life cycle A balanced system solution that satisfies the needs of the customer. To accompany these characteristics. system engineering provides an interdisciplinary organization but is still flexible in many ways. This paper introduces the ideas of the system and the significance of the life cycle in developing cost-effective and competitive outlets. In addition, the topic includes definitions that describe system engineering as well as instances of process models. Finally, it finishes with the system engineering method, which is used in aircraft design. It begins by defining the concept of a system and then covers the role of the life cycle in the development of competitive and cost-effective goods. This study defines systems engineering and provides an example of a system engineering process model. Finally, it depicts the systems engineering method as used in aircraft design. Advanced design methodology, aircraft conceptual design, design process, design space exploration, functional analysis, requirement analysis, systems design, systems engineering system the life cycle in airplane transactions by investors mostly determined is by objective assessments of the specific aspects that have an effect on its residual value over a given period

Comparative study between interlock nailing and dynamic compression plating in humerus diaphyseal fractures in its functional and surgical outcome

Background: The aim of the study was to analyse compare study between interlock nailing and dynamic compression plating in humerus diaphyseal fractures in its functional and surgical outcome. Methods: The 2019 to 2022, patients were randomly divided into two groups with the help of computer-generated coded envelopes, group A (humerus diaphyseal fractures treated with dynamic compression plating) and group B (humerus diaphyseal fractures treated with interlock nailing) with 20 patients in each group. Outcomes were evaluated based on operative time, blood loss, neurovascular deficit, surgical site infection, union, shoulder stiffness, constant Murley score, Mayo elbow performance index at 1 year of follow up. Results: On radiology as non-union and union, most common study participants show union, on follow up of 1 year constant Murley score and Mayo elbow performance index was calculated and constant Murley score was more in patients treated with dynamic compression plating, shoulder stiffness was more in patients treated with interlock nailing. However blood loss was more in patients treated with dynamic compression plating. Conclusions: The result of our study shows that interlock nailing is associated with less blood loss but it is associated with decreased shoulder function postoperatively and marked shoulder stiffness which is more than patients treated with dynamic compression plating. Hence dynamic compression plating should be considered gold standard for operative treatment of humerus shaft fracture

Uraria picta: A comprehensive review on evidences of utilization and strategies of conservation

Uraria&nbsp;picta&nbsp;(Jacq.) DC. (Prishnaparni) is one of the most important medicinal plants used in different traditional systems of medicines including the Ayurveda and Traditional Chinese medicine. The major use of this plant was found in the most popular Ayurvedic formulation “Dashmula” and in several many other important Ayurvedic formulations. IUCN placed this woody herb in the least concern category as per version 3.1. It has extensive therapeutic uses and pharmacological activities. Though this plant is a source of many phytochemicals, the uses are uncertain because the raw plant parts or crude extracts are being used in all formulations. Therefore, extensive investigations are necessary to focus on the identification of these phytochemicals. It is an urgent need to give special attention to collecting various aspects and more efforts are required in all areas for utilization and conservation of this valuable medicinal herb. Herein, a compilation of all information with various aspects has been presented, including the authors published work on Uraria picta. This review pursues attention towards biological activity, phytochemical profile, utilization, propagation and conservation of Uraria picta

PATH FINDER PROCESS VALIDATION OF MOIST HEAT STERILIZER IN PARENTRAL MANUFACTURING UNIT

Objective:- Moist heat sterilization is the most important in pharmaceutical Parentral manufacturing unit. Sterile products have several unique dosage form properties, such as freedom from microorganisms, freedom from pyrogens, freedom from particulates, and extremely high standards of purity and quality; however, the ultimate goal in the manufacture of a sterile product is absolute absence of microbial contamination. An attempt has been made in this research work to validate the Moist Heat Steriliser with technical  parameters  classified as Critical and Variable Parameters. Method:- Moist Heat Sterilization method is used for Sterilization of  Accessories,Garments ,Silicon tubes, filtration assembly etc. on basis of coagulation of cell proteins. Moist Heat Steriliser  is validated every half year to ensure the system is liable to consistently, provide dehydrogenated or sterile product and meets the quality standards. Validation is done by proper planning by taking regular load and experimental load of regular batches of the product. The study is done on Heat distribution, Heat penetration, and Bio burden determination, Minimize the utility cost, and Man hours during sterilization cycle. Result:- The result found in this research work  leads to setting up New approach to Validate Moist Heat Steriliser in Parentral manufacturing unit with cost effective way. Conclusion:- The Path finder validation process setup through this project is Cost saving through Energy as well as Man Hour Saving and Breakage of Units also maintain Sterility in product. It is helpful to find out Hot and Cold Spots in Moist Heat sterilizer and Designing and   Placement of RTDs. The findings were submitted to the Parentral Department of Vital HealthCare Pvt. Ltd., Satpur. MIDC, Nashik. KEYWORDS:-Moist heat Sterilization , Process Validation , Critical and Variable parameters

Sustainabot – Exploring the Use of Everyday Foodstuffs as Output and Input for and with Emergent Users

Mainstream digital interactions are spread over a plethora of devices and form-factors, from mobiles to laptops; printouts to large screens. For emergent users, however, such abundance of choice is rarely accessible or affordable. In particular, viewing mobile content on a larger screen, or printing out copies, is often not available. In this paper we present Sustainabot – a small robot printer that uses everyday materials to print shapes and patterns from mobile phones. Sustainabot was proposed and developed by and with emergent users through a series of co-creation workshops. We begin by discussing this process, then detail the open-source mobile printer prototype. We carried out two evaluations of Sustainabot, the first focused on printing with materials in situ, and the second on understandability of its output. We present these results, and discuss opportunities and challenges for similar developments. We conclude by highlighting where and how similar devices could be used in future. © 2019 Copyright held by the owner/author(s)

Moving Object Detection in Low-Illuminance Video

The security is a main threat exists in every real-time system. The systems like disaster-prevention, crime-prevention and boarder security needs highly secured mechanism to alert the people about the incident happening in near about area. Camera system is widely used to monitor the area where security is crucial like for disaster-prevention and crime-prevention. However, at low-illuminance condition, the performance of normal cameras is degrade in great extent. At low-illuminance condition night vision cameras are developed and used but they do not support moving object detection. Also the Gaussian filter technique is used in the system requires the large amount of calculation so the time requirement is also large. Therefore, it is conceivable that the Gaussian filter is not suitable for real time video processing. In this system, input which is low-illuminance video is first denoised using a moving average filter. In that candidate regions of moving object are found by differencing between transformed current image and recent previous image. Moving object is finally decided by combined feature set and motion analysis. Object is tracked by matching object components in ROI. In the motion detection for low-light video images, it is possible to improve the accuracy of recognition by intensity correction and noise removal as preparation. After the detection security system will generate the alert

Outcomes of resection for rectal cancer in India: The impact of the double stapling technique

BACKGROUND: The introduction of circular staplers into colorectal surgery has revolutionized anastomotic techniques stretching the limits of sphincter preservation. Data on the double-stapling technique (DST) has been widely published in the West where the incidence of colorectal cancer is high. However studies using this technique and their results, in the Indian scenario, as well as the rest of Asia, have been few and far between. AIM: To evaluate the feasibility of the DST in Indian patients with low rectal cancers and assess its impact on anastomotic leak rates, covering colostomy rates, level of resection and morbidity in patients undergoing low anterior resection (LAR). METHODS: A comparative analysis was performed between retrospectively acquired data on 78 patients (mean age 53.2 ± 13.5 years) undergoing LAR with the single-stapling technique (SST) (between January 1999 and December 2001) and prospective data acquired on 138 LARs (mean age 50.3 ± 13.9 years) performed using the DST (between January 2003 – December 2005). RESULTS: A total of 77 out of 78 patients in the SST group had Astler Coller B and C disease while the number was 132/138 in the DST group. The mean distance of the tumor from anal verge was 7.6 cm (2.5–15 cm) and 8.0 cm (4–15 cm) in the DST and SST groups, respectively. In the DST group, there were 5 (3.6%) anastomotic failures and 62 (45%) covering stomas compared to 7 (8.9%) anastomotic failures and 51 (65.4%) covering stomas in the SST group. The anastomotic leak rate, though objectively lower in the DST group, did not attain statistical significance (p = 0.12). Covering stoma rates were significantly lower in DST group (p = 0.006). There was 1 death in the DST group due to cardiac causes (unrelated to the anastomosis) and no mortality in the SST group. The LAR and abdominoperineal resection (APR) rates were 40% and 60%, respectively, during 1999–2001. In 2005, these rates were 55% and 45%, respectively. CONCLUSION: This study, perhaps the first from India, demonstrates the feasibility of the DST in a country where the incidence of colorectal cancer is increasing. Since the age at presentation is at least a decade younger than the Western world, consideration of sphincter preservation assumes greater significance. The observed improvement of surgical outcomes with DST needs further studies to significantly prove these findings in a population where the tumors at presentation are predominantly Astler Coller Stage B and C