1,283 research outputs found

    Pessimistic Software Lock-Elision

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    Read-write locks are one of the most prevalent lock forms in concurrent applications because they allow read accesses to locked code to proceed in parallel. However, they do not offer any parallelism between reads and writes. This paper introduces pessimistic lock-elision (PLE), a new approach for non-speculatively replacing read-write locks with pessimistic (i.e. non-aborting) software transactional code that allows read-write concurrency even for contended code and even if the code includes system calls. On systems with hardware transactional support, PLE will allow failed transactions, or ones that contain system calls, to preserve read-write concurrency. Our PLE algorithm is based on a novel encounter-order design of a fully pessimistic STM system that in a variety of benchmarks spanning from counters to trees, even when up to 40% of calls are mutating the locked structure, provides up to 5 times the performance of a state-of-the-art read-write lock.National Science Foundation (U.S.) (Grant 1217921

    Accuracy of magnetic resonance studies in the detection of chondral and labral lesions in femoroacetabular impingement : systematic review and meta-analysis

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    Background: Several types of Magnetic resonance imaging (MRI) are commonly used in imaging of femoroacetabular impingement (FAI), however till now there are no clear protocols and recommendations for each type. The aim of this meta-analysis is to detect the accuracy of conventional magnetic resonance imaging (cMRI), direct magnetic resonance arthrography (dMRA) and indirect magnetic resonance arthrography (iMRA) in the diagnosis of chondral and labral lesions in femoroacetabular impingement (FAI). Methods: A literature search was finalized on the 17th of May 2016 to collect all studies identifying the accuracy of cMRI, dMRA and iMRA in diagnosing chondral and labral lesions associated with FAI using surgical results (arthroscopic or open) as a reference test. Pooled sensitivity and specificity with 95% confidence intervals using a random-effects meta-analysis for MRI, dMRA and iMRA were calculated also area under receiver operating characteristic (ROC) curve (AUC) was retrieved whenever possible where AUC is equivocal to diagnostic accuracy. Results: The search yielded 192 publications which were reviewed according inclusion and exclusion criteria then 21 studies fulfilled the eligibility criteria for the qualitative analysis with a total number of 828 cases, lastly 12 studies were included in the quantitative meta-analysis. Meta-analysis showed that as regard labral lesions the pooled sensitivity, specificity and AUC for cMRI were 0.864, 0.833 and 0.88 and for dMRA were 0.91, 0.58 and 0.92. While in chondral lesions the pooled sensitivity, specificity and AUC for cMRI were 0.76, 0.72 and 0.75 and for dMRA were 0.75, 0.79 and 0.83, while for iMRA were sensitivity of 0.722 and specificity of 0.917. Conclusions: The present meta-analysis showed that the diagnostic test accuracy was superior for dMRA when compared with cMRI for detection of labral and chondral lesions. The diagnostic test accuracy was superior for labral lesions when compared with chondral lesions in both cMRI and dMRA. Promising results are obtained concerning iMRA but further studies still needed to fully assess its diagnostic accuracy

    The All-Data-Based Evolutionary Hypothesis of Ciliated Protists with a Revised Classification of the Phylum Ciliophora (Eukaryota, Alveolata)

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    This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ The file attached is the published version of the article

    The effect of axial load on the sagittal plane curvature of the upright human spine in vivo

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    Copyright © 2008 Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in Pattern Recognition . Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Biomechanics, Vol. 41 Issue 13 (2008), DOI: 10.1016/j.jbiomech.2008.06.035Determining the effect of load carriage on the human spine in vivo is important for determining spinal forces and establishing potential mechanisms of back injury. Previous studies have suggested that the natural curvature of the spine straightens under load, but are based on modelling and external measurements from the surface of the back. In the current study, an upright positional MRI scanner was used to acquire sagittal images of the lumbar and lower thoracic spine of 24 subjects. The subjects were imaged in standing whilst supporting 0, 8 and 16 kg of load which was applied axially across the shoulders using an apron. An active shape model of the vertebral bodies from T10 to S1 was created and used to characterise the effect of load. The results from the shape model showed that the behaviour of the average-shaped spine was to straighten slightly. However, the shape model also showed that the effect of load exhibited systematic variation between individuals. Those who had a smaller than average curvature before loading straightened under load, whereas those who had a greater than average curvature before loading showed an increase in curvature under load. The variation in behaviour of differently shaped spines may have further implications for the effects of load in lifting manoeuvres and in understanding the aetiology of back pain

    Impacts of climate change and its uncertainties on the renewable energy generation and energy demand in urban areas

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    This work investigates the effects of future climate uncertainties in calculating the heating and cooling demand of buildings and estimating potentials for renewable energy generation (solar PV and wind). The building stock of Lund in Sweden is considered for energy simulations and for future climate, the most recent outputs of RCA4, which is the 4th generation of the Rossby Centre regional climate model (RCM), is used considering several two representative concentration pathways (RCPs) and four global climate models (GCMs). Simulations and assessment are performed for three 30-year time periods, from 2010 until 2099. Through comparing distributions of data sets, it is found that the uncertainty induced by climate models affects the estimation of renewable energy generation more than those induced by time periods. Changes in the heating demand due to climate change and uncertainties are surprisingly low while it is very large for cooling demand. This can be because of having a good quality for buildings on the average, however this should be more investigated for other cities in Sweden

    Effect of different levels and particle sizes of perlite on serum biochemical factors of broiler chicks

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    The objective of this study was to investigate the effects of different levels and particle sizes of perlite in broiler chicks’ diets on serum biochemical factors. For the stated purpose, 280 day-old Ross 308 broiler chicks were allocated to seven treatments and four replications in a factorial experiment on the basis of randomized complete block design. One factor consisted of two levels (perlite particle sizes of 1.5 and 3 mm) and the other factor included three levels of perlite (1, 3 and 5% of diet). A control treatment with no perlite was also included in the experiment. Based on the results obtained, the perlite levels and particle sizes did not affect the serum Ca, P, Cl, Na and Fe, however, they influenced the serum Mg and K significantly (P < 0.05). It seems that perlite did not have any major impact on the biochemical factors of chick's serum.Key words: Perlite, aluminosilicate, particle size, serum biochemical factors

    “Conjugate Channeling” Effect in Dislocation Core Diffusion: Carbon Transport in Dislocated BCC Iron

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    Dislocation pipe diffusion seems to be a well-established phenomenon. Here we demonstrate an unexpected effect, that the migration of interstitials such as carbon in iron may be accelerated not in the dislocation line direction [symbol], but in a conjugate diffusion direction. This accelerated random walk arises from a simple crystallographic channeling effect. [c] is a function of the Burgers vector b, but not [symbol], thus a dislocation loop possesses the same everywhere. Using molecular dynamics and accelerated dynamics simulations, we further show that such dislocation-core-coupled carbon diffusion in iron has temperature-dependent activation enthalpy like a fragile glass. The 71° mixed dislocation is the only case in which we see straightforward pipe diffusion that does not depend on dislocation mobility.National Science Foundation (U.S.) (Grant No. CMMI-0728069)National Science Foundation (U.S.) (Grant No. DMR-1008104)National Science Foundation (U.S.) (Grant No. DMR-1120901
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